Orbit, a novel microtubule-associated protein essential for mitosis in 3Drosophila melanogaster

Journal of Cell Biology

Volumn 149, Issue 1, 2000, Pages 153-165

  Inoue, Yoshihiro H ^a,b,d   Avides, Maria Do Carmo ^b,c   Shiraki, Michina ^a,e   Deak, Peter ^b,c   Yamaguchi, Masamitsu ^a   Nishimoto, Yoshio ^a   Matsukage, Akio ^a   Glover, David M ^b,c  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d KYOTO INSTITUTE OF TECHNOLOGY   (Japan)

^e NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

Centrosome; Drosophila melanogaster; Microtubule associated protein; Mitosis; Mitotic spindle

Indexed keywords

MICROTUBULE PROTEIN;

ALLELE; ANIMAL CELL; ARTICLE; CENTROSOME; CYTOKINESIS; DROSOPHILA MELANOGASTER; GENE EXPRESSION; MICROTUBULE; MITOSIS; NONHUMAN; POLYPLOIDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; SYNCYTIOTROPHOBLAST;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; CENTRAL NERVOUS SYSTEM; CHROMOSOMES; CONSERVED SEQUENCE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENES, INSECT; GUANOSINE TRIPHOSPHATE; INSECT PROTEINS; LARVA; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; PHYSICAL CHROMOSOME MAPPING; POLYPLOIDY; RNA, MESSENGER;

ANIMALIA; DROSOPHILA MELANOGASTER; HEXAPODA; MELANOGASTER;

EID: 0342657750     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.149.1.153     Document Type: Article

References (58)

1. Adams, R.R., A.A. Tavares, A. Salzberg, H.J. Bellen, and D.M. Glover. 1998. pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis. Genes Dev. 12:1483-149-4.
2. Aizawa, H., Y. Emori, H. Murofushi, H. Kawasaki, H. Sakai, and K. Suzuki, 1990. Molecular cloning of a ubiquitously distributed microtubule-associated protein with Mr 190,000. J. Biol Chem. 265:13849-13855.
3. Andersen, S.S., and E. Karsenti. 1997. XMAP310: a Xenopus rescue-promoting factor localized to the mitotic spindle. J. Cell Biol. 139:975-983.
4. Andersen, S.S., B. Buendia, J.E. Dominguez, A. Sawyer, and E. Karsenti. 1994. Effect on microtubule dynamics of XMAP230, a microtubule-associated protein present in Xenopus laevis eggs and dividing cells. J. Cell Biol. 127: 1289-1299.
5. Barton, N.R., A.J. Pereira, and L.S. Goldstein. 1995. Motor activity and mitotic spindle localization of the Drosophila. Mol. Biol. Cell. 6:1563-1574.
6. Belmont, L.D., and T.J. Mitchison. 1996. Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules. Cell. 84:623-631.
7. Biggs, J., E. Hersperger, P.S. Steeg, L.A. Liotta, and A. Shearn. 1990. A Drosophila gene that is homologous to a mammalian gene associated with tumor-metastasis codes for a nucleosidc diphosphate kinase. Cell. 63:933-940.
8. Brand, A.H., and N. Perrimon. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development. 118: 401-415.
9. Burns, R.G., and K.W. Farrell. 1996. Getting to the heart of β-tubulin. Trends Cell Biol. 6:297-303.
10. Cavener, D.R., and B.A. Cavener. 1993. Translation start sites and mRNA leaders. In An Atlas of Drosophila Genes. G. Maroni, editor. Oxford University Press, New York, 359-377.
11. Charrasse, S., M. Schroeder, C. Gauthier-Rouviere, F. Ango, L. Cassimeris, D.L. Gard, and C. Larroque. 1998. The TOGp protein is a new human microtubule-associated protein homologous to the Xenopus XMAP215. J. Cell Sci. 111:1371-1383.
12. Deak, P., M.M. Omar, R.D. Saunders, M. Pal, O. Komonyi, J. Szidonya, P. Maroy, Y. Zhang, M. Ashburner, P. Benos, et al. 1997. P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogasten correlation of physical and cytogenetic maps in chromosomal region 86F.-87F. Genetics. 147:1697-1722.
13. Desai, A., and T.J. Mitchison. 1997. Microtubule polymerization dynamics. Annu. Rev. Cell Dev. Biol. 13:83-117.
14. Desai, A., S. Verma, T.J. Mitchison, and C. Walczak. 1999. Kin 1 kinesins are microtubule-destabilizing enzymes. Cell. 96:69-78.
15. Frasch, M. 1991. The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homolog of the vertebrate gene regulator of chromatin condensation, RCCI. EMBO (Eur. Mol. Biol. Organ.) J. 10:1225-1236.
16. Frasch, M., D.M. Glover, and H. Saumweber. 1986. Nuclear antigens follow different pathways into daughter nuclei during mitosis in early Drosophila embryos. J. Cell Sci. 82:155-172.
17. Gard, D.L., and M.W. Kirschner. 1987. A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end. J. Cell Biol. 105:2203-2215.
18. Gatti, M., and B.S. Baker. 1989. Genes controlling essential cell-cycle function in Drosophila melanogaster. Genes Dev. 3:438-453.
19. Glover, D.M., M.H. Leibowitz, D.A. McLean, and H. Parry. 1995. Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles. Cell. 81:95-105.
20. Gonzalez, C. and D.M. Glover 1993. Techniques for studying mitosis in Drosophila. In The Cell Cycle: A Practical Approach. R. Brook and P. Fantes, editors. IRL Press, Oxford. 163-168.
21. Gonzalez, C., J. Casal, and P. Ripoll. 1988. Functional monopolar spindles caused by mutation in mgr, a cell division gene of Drosophila melanogaster. J. Cell Sci. 89:39-17.
22. Gonzalez, C., R.D.C. Saunders, J. Casal, I. Molina, M. Carmena, P. Ripoll, and D.M. Glover. 1990. Mutations at the asp locus of Drosophila leads to multiple free centrosomes in syncytial embryos, but restrict centrosome duplication in larval neuroblasts. J. Cell Sci. 96:605-616.
23. Harlow, F., and E. Lane. 1988. Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor Press, NY.
24. Harlman, J.J., J. Mahr, K. McNally, K. Okawa, A. Iwamatsu, S. Thomas, S. Cheesman, J. Heuser, R.D. Vale, and F.J. McNally. 1998. Katanin, a microtubule-severing protein, is a novel ATPase that targets to the centrosome using a WD40-containing subunit. Cell. 93:277-287.
25. Heck, M.M., A. Pereira, P. Pesavento, Y. Yannoni, A.C. Spradling, and L.S. Goldstein. 1993. The kinesin-like protein KLP61F is essential for mitosis in Drosophila. J. Cell Biol. 123:665-679.
26. Heino, T.I., A.O. Saura, and V. Sorsa. 1994. Salivary gland chromosome maps. Drosophila Information Service. 1994:619-738.
27. Hyman, A.A., and E. Karsenti. 1996. Morphogenetic properties of microtubules and mitotic spindle assembly. Cell. 84:401-410.
28. Inoue, Y.H. and D.M. Glover. 1998. Involvement of the rolled/MAP kinase gene in Drosophila mitosis: interaction between genes for the MAP kinase cascade and abnormal spindle. Mol. Gen. Genet. 258:334-341.
29. Ishikawa, K., T. Nagase, M. Suyama, N. Miyajima, A. Tanaka, H. Kotani, N. Nomura, and O. Ohara. 1998. Prediction of the coding sequences of unidentified human genes. DNA Res. 5:169-176.
30. Kellogg, D.R., and K.M. Alberts. 1992. Purification of a multiprotein complex containing centrosomal proteins from the Drosophila embryo by chromatography with low-affinity polyclonal antibodies. Mol. Biol. Cell. 3:1-11.
31. Kellogg, D.R., C.M. Field, and B.M. Alberts. 1989. Identification of microtubule-associated proteins in the centrosome, spindle, and kinetochore of the early Drosophila embryo. J. Cell Biol. 109:2977-2991.
32. Lu, C., J. Stricker, and H.P. Erickson. 1998. FtsZ from Escherichia coli, Azobacter vinelandii, and Thermotoga maritima: quantitation, GTP hydrolysis and assembly. Cell Motil. Cytoskel. 40:71-86.
33. Marklund, U., N. Larsson, H.M. Gradin, G. Brattsand, and M. Gullberg. 1996. Oncoprotein 18 is a phosphorylation-responsive regulator of microtubule dynamics. EMBO (Eur. Mol. Biol. Organ.) J. 15:5290-5298.
34. Miller, K.G., C.M. Field, and B.M. Alberts. 1989. Actin-binding proteins from Drosophila embryos: a complex network of interacting proteins detected by F-actin affinity chromatography. J. Cell Biol. 109:2963-2975.
35. Mukherjee, A., and J. Lutkenhaus. 1998. Dynamic assembly of FtsZ regulated by GTP hydrolysis. EMBO (Eur. Mol. Biol. Organ.) J. 17:462-446.
36. Muller-Reichert, T., D. Chretien, F. Severin, and A.A. Hyman. 1998. Structural changes at microtubule ends accompanying GTP hydrolysis: information from a slowly hydrolyzable analogue of GTP. gunylyl(alpha.beta)methylenediphosphate. Proc. Natl. Acad. Sci. USA 95:3661-3666.
37. Nogales, E., K.H. Downing, L.A. Amos, and J. Lowe. 1998. Tubulin and FtsZ form a distinct family of GTPases. Nat. Struct. Biol. 5:451-458.
38. Nogales, F., M. Whittaker, R.A. Milligan, and K.H. Downing. 1999. High-resolution model of the microtubule. Cell. 96:79-88.
39. Olson, K. R., J.R. McIntosh, and J.B. Olmsted. 1995. Analysis of MAP4 function in living cells using green fluorescent protein (GFP) chimeras. J. Cell Biol. 130:639-650.
40. cdc2 kinase to microtubules and is a potential regulator of M-phase microtubule dynamics. J. Cell Biol. 128:849-862.
41. Pasqualone, D., and T.C. Huffaker 1994. STU1, a suppressor of a β-tubulin mutation, encodes a novel and essential component of the yeast mitotic spindle. J. Cell Biol. 127:1973-1984.
42. Pedrotti, B., L. Ulloa, J. Avila, and K. Islam. 1996. Characterization of microtubule-associated protein MAP1B: phosphorylation state, light chains, and binding to microtubules. Biochemistry. 35:3016-3023.
43. Rothwell, W.F., P. Fogarty, C.M. Field, and W. Sullivan. 1998. Nuclear-fallout, a Drosophila protein that cycles from the cytoplasm to the centrosomes, regulates cortical microfilament organization. Development. 125:1295-1303.
44. Salimnia, H., A. Radia, S. Bernatchez, T.J. Beveridge, J.R. Dillon. 2000. Characterization of the fisZ cell division gene of Neisseria gonorrhoeae: expression in Escherichia coli and N. gonorrhoeae. Arch. Microbiol. 173:10-20.
45. Saunders, R.D.C., M.C. Avides, T. Howard, C. Gonzalez, and D.M. Glover. 1997. The Drosophila gene abnormal spindle encodes a novel microtubule-associated protein that associates with the polar regions of the mitotic spindle. J. Cell Biol. 137:881-890.
46. Sharp, D.J., K.L. McDonald, H.M. Brown, H.J. Matthies, C. Walczak, R.D. Vale, T.J. Mitchison, and J.M. Scholey. 1999a. Visualization of the bipolar kinesin. KLP61F, on microtubule bundles within spindles of Drosophila early embryos. J. Cell Biol. 144:125-138.
47. Sharp, D.J., K.R. Yu, J.C. Sisson, W. Sullivan, and J. Scholey. 1999b. Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos. Nature Cell Biol. 1:51-54.
48. Shiina, N., and S. Tsukita. 1999. Mutations at phosphorylation sites of Xenopus microtubule-associated protein 4 affect its microtubule-binding ability and chromosome movement during mitosis. Mol. Biol. Cell. 10:597-608.
49. Sullivan, W., P. Fogarty, and W. Theurkauf. 1993. Mutations affecting the cytoskeletal organization of syncytial Drosophila embryos. Development. 118: 1245-1254.
50. Sunkel, C.E., and D.M. Glover. 1988. polo, a mitotic mutant of Drosophila displaying abnormal spindle poles. J. Cell Sci. 89:25-38.
51. Tokuraku, K., M. Katsuki, H. Nakagawa, and S. Kotani. 1999. A new model for microtubule-associated protein (MAP)-induced microtubule assembly. The Pro-rich region of MAP4 promotes nucleation of microtubule assembly in vitro. Eur. J. Biochem. 259:158-166.
52. Vasquez, R.J., D.L. Gard, and L. Cassimeris. 1994. XMAP from Xenopus eggs promotes rapid plus end assembly of microtubules and rapid microtubule polymer turnover. J. Cell Biol. 127:985-993.
53. Vulevic, B., and J.J. Correia. 1997. Thermodynamic and structural analysis of microtubule assembly: the role of GTP hydrolysis. Biochemistry. 36:1357-1375.
54. Vulevic, B., S. Lober, and J.J. Correia. 1997. Role of guanine nucleotides in the vinblastin-induced self-association of tubulin: effects off guanosine alpha, bcta-methylenetrisphosphate and guanosine alpha, beta-methylenediphosphate. Biochemistry. 36:12828-12835.
55. White-Cooper, H., M.A. Schafer, L.S. Alphey, and M.T. Fuller. 1998. Transcriptional and post-transcriptional control mechanisms coordinate the onset of spermatid differentiation with meiosis I in Drosophila. Development. 125:125-134.
56. Whilfield, W.G., S.F. Millar, H. Saumweber, M. Frasch, and D.M. Glover. 1988. Cloning of a gene encoding an antigen associated with the centrosome in Drosophila. J. Cell Sci. 89:467-480.
57. Williams, B.C., M.F. Riedy, E.V. Williams, M. Gatti, and M.L. Goldberg. 1995. The Drosophila kinesin-like protein KLP3A is a midbody component. J. Cell Biol. 129:709-723.
58. Wilson, R., R. Ainscough, K. Anderson, C. Baynes, M. Berks, J. Bonfield, J. Burton, M. Connell, T. Copsey, and J. Cooper. 1994. 2.2Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature. 368:32-38.