Family and genetic studies on the relationship of schizophrenia to affective disorders

European Archives of Psychiatry and Clinical Neuroscience

Volumn 249, Issue SUPPL. 4, 1999, Pages

  Maier, Wolfgang ^a   Rietschel, Marcella ^b   Lichtermann, Dirk ^b   Wildenauer, Dieter B ^a  

^a UNIVERSITY OF BONN   (Germany)

^b NONE

Author keywords

Affective disorders; Family studies; Linkage studies; Obligate carriers; Schizophrenia

Indexed keywords

AFFECTIVE NEUROSIS; CHROMOSOME 10; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME 22; CONFERENCE PAPER; FAMILY STUDY; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HETEROZYGOTE; HUMAN; HYPOTHESIS; MANIC DEPRESSIVE PSYCHOSIS; PHENOTYPE; PRIORITY JOURNAL; SCHIZOPHRENIA;

EID: 0342545933     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/pl00014186     Document Type: Conference Paper

References (35)

1. Berrettini WH, Ferraro TN, Goldin LR, Weeks DE, Detera-Wadleigh S, Nurnberger JI, Gershon ES (1994) Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene. Proc Natl Acad Sci USA 91:5918-5921
2. Berrettini WH, Vuoristo J, Ferraro TN, Buono RJ, Wildenauer D, Ala-Kokko L (1998) Human G(olf) gene polymorphisms and vulnerability to bipolar disorder. Psychiatr Genet 8: 235-238
3. Blouin J-L, Dombroski BA, Nath SK, Lasseter VK, Wolyniec PS, Nestadt G, Thornquist M, Ullrich G, McGrath J, Kasch L, et al. (1998) Schizophrenia susceptibility loci on chromosome 13q32 and 8p21. Nat Genet 20: 70-73
4. Collins A, Teague SA, Lio P, Morton NE (1997) The genetic location database. www.//cedar.genetics.soton.ac.uk/public_html
5. Erlenmeyer-Kimling L, Adamo UH, Rock D, Roberts SA, Bassett AS, Squires-Wheeler E, Cornblatt BA, Endicott J, Pape S, Gottesman II (1997) The New York High-Risk Project: Prevalence and comorbidity of axis I disorders in offspring of schizophrenic parents at 25-year follow-up. Arch Gen Psychiatry 54: 1096-1102
6. Faraone SV, Matise T, Svrakic D, Pepple J, Malaspina D, Suarez B. Hampe C, Zambuto CT, Schmitt K, Meyer J, et al. (1998) Genome scan of European-American schizophrenia pedigrees: results of the NIMH Genetics Initiative and Millenium Consortium. Am J Med Genet 81:290-295
7. Foroud T, Castellucio PF, Koller DL, Edenberg HJ, Goate A, Detera-Wadleigh S, Stine OC, McMahon FJ, Mclnnis MG, Rice J, et al. (1998) Genomewide scan of affected relative pairs using the NIMH Genetics Initiative Bipolar Affective Disorder pedigrees. Am J Med Genet 81:462
8. Gershon ES, DeLisi LE, Hamovit J, Nurnberger JI jr, Maxwell ME, Schreiber J, Dauphinais D, Dingman CW, Guroff JJ (1988) A controlled family study of chronic psychoses. Arch Gen Psychiatry 45:328-336
9. Goldberg R, Motzkin B, Marion R, Scambler PJ, Shprintzen RJ (1993) Velo-cardio-facial syndrome: a review of 120 patients. Am J Med Genet 45:313-319
10. Kelsoe JR, Loetscher E, Spence MA, Foguet M, Sadovnick AD, Remick RA, Flodman P, Masser D, Ungerleider S, Rapaport MH, et al. (1998) A genome survey of bipolar disorder indicates a susceptibility locus on chromosome 22. Am J Med Genet 81:461-462
11. Kendler KS, Gardner CO (1997) The risk for psychiatric disorders in relatives of schizophrenic and control probands: a comparison of three independent studies. Psychol Med 27:411-419
12. Kendler KS, McGuire M, Gruenberg AM, O'Hare A, Spellman M, Walsh D (1993a) The Roscommon Family Study: I. Methods, diagnosis of probands and risk of schizophrenia in relatives. Arch Gen Psychiatry 50:527-540
13. Kendler KS, McGuire M, Gruenberg AM, Spellman M, O'Hare A, Walsh D (1993b) The Roscommon Family Study: II. The risk of nonschizophrenic nonaffective psychoses in relatives. Arch Gen Psychiatry 50:645-652
14. Kety SS, Wender P, Jacobsen B, Ingraham LJ, Jansson L, Faber B, Kinney DK (1994) Mental illness in the biological and adoptive relatives of schizophrenic adoptees: replication of the Copenhagen study in the rest of Denmark. Arch Gen Psychiatry 51:442-455
15. Kraepelin E (1913) Psychiatrie. Ein Lehrbuch für Studierende und Ärzte. Bd. III: Klinische Psychiatrie. Teil II. Barth, Leipzig
16. Lander ES, Kruglyak L (1995) Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nature Genet 11:241-247
17. Levinson DF, Coon H (1998) Chromosome 22 workshop. Psychiatr Genet 8:115-120
18. Lin M-W, Curtis D, Williams N, Arranz M, Nanko S, Collier D et al. (1995) Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32. Psychiatr Genet 5:117-126
19. Maier W, Lichtermann D, Minges J, Hallmayer J, Heun R, Benkert O, Levinson DF (1993) Continuity and discontinuity of affective disorders and schizophrenia. Results of a controlled family study. Arch Gen Psychiatry 50:871-883
20. McGuffin P, Asherson P, Owen M, Farmer A (1994) The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia? Br J Psychiatry 164: 593-599
21. Nöthen MM, Cichon S, Rohleder H, Hemmer S, Franzek E, Fritze J, Albus M, Borrmann-Hassenbach M, Kreiner R, Weigelt B, et al. (1999) Evaluation of linkage of bipolar affective disorder to chromosome 18 in a sample of 57 German families. Mol Psychiatry 4:76-84
22. Parnas J, Cannon TD, Jacobsen B, Schulsinger H, Schulsinger F, Mednick SA (1993) Lifetime DSM-III-R diagnostic outcomes in the offspring of schizophrenic mothers: Results from the Cogenhagen high risk study. Arch Gen Psychiatry 50:707-714
23. Pulver AE, Karyiorgou M, Wolyniec P, Lasseter VK, Kasch L, Nestadt G, Antonarakis S, Housman D, Kazazian HH, Meyers D, et al. (1994) Sequential strategy to identify a susceptibility gene for schizophrenia: report of potential linkage for schizophrenia on chromosome 22q12-q13.1. Am J Med Genet 54: 36-43
24. Rice JP, Goate A, Williams JT, Bierut L, Dorr D, Wu W, Shears S, Gopalakrishnan G, Edenberg HJ, Foroud T, et al. (1997) Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 1,6,8,10, and 12. Am J Med Genet 74:247-253
25. Schwab SG, Hallmayer J, Albus M, Lerer B, Hanses C, Kanyas K, Segman R, Borrman M, Dreikorn B, Lichtermann D, et al. (1998a) Further evidence for a susceptibility locus on chromosome 10p14-p11 in 72 families with schizophrenia by nonparametric linkage analysis. Am J Med Genet 81:302-307
26. Schwab SG, Hallmayer J, Lerer B, Albus M, Borrmann M, Honig S, Strauß M, Segman R, Lichtermann D, Knapp M, et al. (1998b) Support for a locus on chromosome 18p conferring susceptibility to functional psychosis in families with schizophrenia by association and linkage analysis. Am J Hum Genet 63:1139-1152
27. Spielman RS, Ewens WJ (1996) The TDT and other family-based tests for linkage disequilibrium and association. Am J Hum Genet 59:983-989
28. Squires-Wheeler E, Skodol AE, Basett A, Erlenmeyer-Kimling L (1989) DSM-III-R schizotypal personality traits in offspring of schizophrenic disorder, affective disorder, and normal control parents. J Psychiatr Res 23:229-239
29. Stine OC, Xu J, Koskela R, McMahon FJ, Gschwend M, Friddle C, Clark CD, Mclnnis MG, Simpson SG, Breschel TS, et al. (1995) Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. Am J Hum Genet 57:1384-1394
30. Straub RE, MacLean CJ, Martin RB, Ma Y, Myakishev MV, Harris-Kerr C, Webb BT, O'Neill FA, Walsh D, Kendler KS (1998) A schizophrenia locus may be located in region 10p15-p11. Am J Med Genet 81:296-301
31. Taylor MA (1992) Are schizophrenia and affective disorder related? A selective literature review. Am J Psychiatry 149: 22-32
32. Taylor MA, Amir N (1994) Are schizophrenia and affective disorder related?: the problem of schizoaffective disorder and the discrimination of the psychoses by signs and symptoms. Compr Psychiatry 35:420-429
33. Thaker G, Adami H, Moran M, Lahti A, Cassady S (1993) Psychiatric illness in families of subjects with schizophrenia-spectrum personality disorders: high morbidity risks for unspecified functional psychoses and schizophrenia. Am J Psychiatry 150: 66-71
34. Tsuang MT, Winokur G, Crowe RR (1980) Morbidity risks of schizophrenia and affective disorders among first-degree relatives of patients with schizophrenia, mania, depression and surgical conditions. Br J Psychiatry 137:497-504
35. Yoshikawa T, Turner G, Esterling LE, Sanders AR, DeteraWadleigh SD (1997) A novel human myo-inositol monophosphatase gene, IMP.18p, maps to a susceptibility region for bipolar disorder. Mol Psychiatry 2:393-397