Pneumonia in the elderly - What makes the difference?

Wiener Klinische Wochenschrift

Volumn 112, Issue 13, 2000, Pages 566-575

  Schäfer, Harald ^a   Ewig, Santiago ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Antimicrobial treatment; Elderly; Etiology; Mortality; Pneumonia

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMINOPENICILLIN; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE INHIBITOR; CEPHALOSPORIN DERIVATIVE; CILASTATIN PLUS IMIPENEM; CLAVULANIC ACID; INFLUENZA VACCINE; MACROLIDE; PIPERACILLIN PLUS TAZOBACTAM; PNEUMOCOCCUS VACCINE; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANTIMICROBIAL THERAPY; BACTERIAL PNEUMONIA; COMORBIDITY; CONFUSION; ELDERLY CARE; HUMAN; INFLUENZA; MALNUTRITION; MORTALITY; PHYSICAL EXAMINATION; REVIEW; RISK FACTOR; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE; THORAX RADIOGRAPHY; TREATMENT OUTCOME;

AGE FACTORS; AGED; ANTI-BACTERIAL AGENTS; CONFUSION; DIAGNOSIS, DIFFERENTIAL; EUROPE; GREAT BRITAIN; HUMANS; PNEUMONIA; PRACTICE GUIDELINES; PREVALENCE; RISK FACTORS; SEVERITY OF ILLNESS INDEX; UNITED STATES; VACCINATION;

EID: 0342323684     PISSN: 00435325     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (65)

1. Oseashon R, Skipper BE, Tempest B (1978) Pneumonia in a Navajo community. A two year experience. Am Rev Respir Dis 117: 1003-1009
2. Marrie TJ (1990) Epidemiology of community-acquired pneumonia in the elderly. Semin Respir Infect 5: 269-275
3. LaCroix AZ, Lipson S, Miles TP, et al (1989) Prospective study of pneumonia hospitalisation and mortality of US older peoples: The role of chronic conditions, health behaviours and nutritional status. Public Health Reports 104: 350-360
4. Marston B, Plouffe JF, File TM, et al (1997) Incidence of community-acquired pneumonia requiring hospitalization. Arch Intern Med 157: 1709-1718
5. Gross PA, Rapuano C, Adrignolo A, et al (1983) Nosocomial infections: Decade specific risks. Infect Control 4: 145-147
6. Hanson L, Weber D, Rutala WA, et al (1992) Risk factors for nosocomial pneumonia in the elderly. Am J Med 92: 161-166
7. Dhar S, Shastri SR, Lenora RAK (1976) Aging and the respiratory system. Med Clin North Am 60: 1121-1139
8. Murasko D, Nelson B, Silver R, et al (1986) Immunologic responses in an elderly population with a mean age of 85. Am J Med 81: 612-618
9. Simons RJ, Reynolds HY (1990) Altered immune status in the elderly. Semin Respir Infect 5: 251-259
10. Riquelme R, Torres A, El-Ebiary M, et al (1997) Community-acquired pneumonia in the elderly: clinical and nutritional aspects. Am J Respir Crit Care Med 156: 1908-1914
11. Koivula I, Sten M, Mäkelä PH (1994) Risk factors for pneumonia in the elderly. Am J Med 96: 313-320
12. Riquelme R, Torres A, El-Ebiary M, et al (1996) Community-acquired pneumonia in the elderly: A multivariate analysis of risk and prognostic factors. Am J Respir Crit Care Med 154: 1450-1455
13. Woodhead M (1994) Pneumonia in the elderly. J Antimicrob Chem 34 [Suppl 34]: 85-92
14. Marrie TJ (1993) Mycoplasma pneumoniae pneumonia requiring hospitalization, with emphasis on infection in the elderly. Arch Intern Med 153:488-494
15. Valenti WM, Trudell RG, Bentley DW (1978) Factors predisposing to oropharyngeal colonization with Gram-negative bacilli in the aged. N Engl J Med 298: 1108-1111
16. Dorff GJ, Rytel MW, Farmer SG, et al (1973) Etiologies and characteristic features of pneumonia in a municipal hospital. Am J Med Sci 266: 349-358
17. Sullivan RJ, Dowdle WR, Marine WM, et al (1972) Adult pneumonia in a general hospital. Etiology and host risk factors. Arch Intern Med 129: 935-942
18. Marrie TJ, Haldane EV, Faulkner R, et al (1985) Community acquired pneumonia requiring hospitalisation - is it different in the elderly? J Am Geriatric Soc 33: 671-680
19. American Thoracic Society (1993) Guidelines for the initial management of adults with community-acquired pneumonia: diagnosis, assessment of severity, and initial antimicrobial therapy. Am Rev Respir Dis 148: 1418-1426
20. British Thoracic Society (1987) The inhospital management of community-acquired pneumonia. Recommendations of the British Thoracic Society. J Royal Coll Phys 21: 267-269
21. Venkatestan P, Gladman J, McFarlane JT, et al (1990) A hospital study of community-acquired pneumonia in the elderly. Thorax 45: 254-258
22. Ruiz M, Ewig S, Marcos MA, Martinez JA, Arancibia F, Mensa J, Torres A (1999) Etiology of community-acquired pneumonia: impact of age, comorbidity, and severity. Am J Respir Crit Care Med 160: 397-405
23. Marrie TJ, Durant H, Yates L (1989) Community acquired pneumonia requiring hospitalisation: 5-year prospective study. Rev Infect Dis 11: 586-599
24. Rouby JJ, Martin De Lassale E, Poete P, Nicolas MH, Bodin L, Jarlier V, Le Charpentier Y, Grosset J, Viars P (1992) Nosocomial bronchopneumonia in the critically ill. Am Rev Respir Dis 146: 1059-1066
25. Fabregas N, Torres A, El-Ebiary M, Ramirez J, Hernandez C, Gonzalez J, Puig de la Bellacasa, Jimenez de Anta MT, Rodriguez-Roisin R (1996) Histopathological and microbiological aspects of ventilator-associated pneumonia. Anaestesiology 84: 260-271
26. American Thoracic Society (1995) Hospital-acquired pneumonia in adults: diagnosis, assessment of severity, initial antimicrobial therapy, and preventive strategies. Am J Respir Crit Care Med 153: 1711-1725
27. Metlay JP, Schulz R, Li YH, et al (1997) Influence of age on symptoms at presentation in patients with community-acquired pneumonia. Arch Intern Med 157: 1453-1459
28. Musgrave T, Verghese A (1990) Clinical features of pneumonia in the elderly. Semin Respir Infect 5: 269-275
29. Marrie TJ, Durant H, Kwan K (1986) Nursing-home acquired pneumonia. J Am Geriatr Soc 34: 697-702
30. McFadden JP, Price RC, Eastwood HD, et al (1982) Raised respiratory rate in elderly patients: A valuable physical sign. Br Med J 284: 626-627
31. Rummans T, Evans J, Krahn L, et al (1995) Delirium in the elderly patients: Evaluation and management. Mayo Clin Proc 70: 989-998
32. Harper G, Newton P (1989) Clinical aspects of pneumonia in the elderly veteran. J Am Geriatr Soc 37: 559-872
33. Fein AM, Niederman MS (1994) Severe pneumonia in the elderly. Clin Geriatr Med 10: 121-141
34. Feldman C (1999) Pneumonia in the elderly. Clin Chest Med 20: 563-573
35. Ewig S, Ruiz M, Mensa J, Marcos MA, Martinez JA, Niederman MS, Torres A (1998) Severe community-acquired pneumonia - assessment of severity criteria. Am J Respir Crit Care Med 158: 1102-1108
36. Fine MJ, Auble TE, Yealy D, et al (1997) A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med 336; 243-250
37. Fine MJ, Smith MA, Carson CA et al (1996) Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis. JAMA 275: 134-141
38. Marrie TJ (1996) Pneumonia in the elderly. Curr Opin Pulm Med 2: 192-197
39. Marrie TJ (1990) Epidemiology of community-acquired pneumonia in the elderly. Semin Respir Infect 5: 269-275
40. Rello J, Rodriguez R, Jubert P, et al (1996) Severe community-acquired pneumonia in the elderly: Epidemiology and prognosis. Clin Infect Dis 23: 723-728
41. Garb JL, Brown RB, Garb JR, et al (1978) Differences in etiology of pneumonias in nursing home and community patients. J A M A 240: 2169-2172
42. Marrie TJ, Blanchard W (1997) A comparison of nursing home-acquired pneumonia patients with patients with community-acquired pneumonia and nursing home patients without pneumonia. J Am Geriatr Soc 45: 50-55
43. Moine P, Vercken JB, Chevret S, et al (1994) Severe community-acquired pneumonia. Etiology, epidemiology, and prognosis factors. Chest 105: 1487-1495
44. British Thoracic Society and the Public Health Laboratory Service (1987) Community-acquired pneumonia in adults in British Hospitals in 1982-1983. A survey of aetiology, mortality, prognostic factors and outcome. Q J Med 239: 195-220
45. Daly, Jencks S, Draper, et al (1990) Predicting hospital associated mortality for medicare patients. A method for patients with stroke, pneumonia, myocardial infarction and congestive heart failure. J A M A 260: 3617-3624
46. Leroy O, Santre C, Beuscart C, et al (1995) A five-year study of severe community-acquired pneumonia with emphasis on prognosis in patients admitted to an intensive care unit. Intens Care Med 21: 24-31
47. Almirall J, Mesalles E, Klamburg J, et al (1995) Prognostic factors of pneumonia requiring admission to the intensive care unit. Chest 107: 511-516
48. Brancati FL, Chow JW, Wagner MM, Vacarello SJ, Yu VL (1993) Is pneumonia really the old man's friend? Two-year prognosis after community-acquired pneumonia: Lancet 342: 30-33
49. Ewig S, Kleinfeld T, Bauer T, Seifert K, Schäfer H, Göke N (1999) Comparative validation of prognostic rules for community-acquired pneumonia in an elderly population. Eur Respir J 14: 370-375
50. Ewig S, Bauer T, Hasper E, et al (1995) Prognostic analysis and predictive rule for outcome of hospital-treated community-acquired pneumonia. Eur Respir J 8: 392-397
51. Koivula I, Sten M, Makela PH (1999) Prognosis after community-acquired pneumonia in the elderly. A population-based 12-year follow-up study. Arch Intern Med 159: 1550-1555
52. Torres A, Aznar R, Gatell JM, Jimenez P, Gonzalez J, Ferrer A, Celis R, Rodrigues-Roisin R (1990) Incidence, risk, and prognostic factors of nosocomial pneumonia in mechanically ventilated patients. Am Rev Respir Dis 142: 523-528
53. Meehan TP, Fine MJ, Krumholz HM, et al (1997) Quality of care, process, and outcomes in elderly patients with pneumonia. JAMA 278: 2080-2084
54. Gleason PP, Meechan TP, Fine JM, Galusha DH, Fine MJ (1999) Association between initial antimicrobial therapy and medical outcomes for hospitalized elderly patients with pneumonia. Arch Intern Med 159: 2562-2572
55. Yuk JH, Nightingale CH, Quintiliani RL (1989) Clinical pharmacokinetics of ceftriaxone. Clin Pharmacokin 17: 223-235
56. Lebel M, Bergeron MG. Pharmacokinetics in the elderly (1987) Studies on ciprofloxacin. Am J Med 82 [Suppl 4A]: 108-114
57. Feinsilver SH, Fein AM, Niederman MS, Schultz DE, Faegenburg DH (1990) Utility of fiberoptic bronchoscopy in nonresolving pneumonia. Chest 98: 1322-1326
58. Mittl RL, Schwab RJ, Duchin JS, goin JE, Albeida SM, Miller WT (1994) Radiographic resolution of community-acquired pneumonia. Am J Respir Crit Care Med 149: 630-635
59. Fedson D, Henrichsen J, Makela PH, Austrian R (1989) WHO recommendations on pneumococcal vaccination: immunization of elderly people with polyvalent pneumococcal vaccine. Infection 17: 431-441
60. Centers for Disease Control and Prevention (1997) Prevention of pneumococcal disease: recommendations of the Advisory Committee on immunization Practices (ACIP). MMWR Morb Mortal Wkly Rep 46 (RR-8): 1-24
61. Ortqvist A, Hedlund J, Burman LA, et al (1998) Randomised trial of 23-valent pneumococcal capsular polysaccharide vaccine in prevention of pneumonia in middle-aged and elderly people. Lancet 351: 399-403
62. Gaillat J, Zmiron D, Mallaret MR, et al (1985) Clinical trial of pneumococcal vaccine among institutionalized elderly. Rev Epidemiol Sante Publique 33: 437-444
63. Koivula I, Sten M, Leinonen M, Makela PH (1997) Clinical efficacy of pneumococcal vaccine in the elderly: a randomized, single-blind population-based trial. Am J Med 103: 281-290
64. Nichol KL, Baken L, Wuorenma J, Nelson A (1999) The health and economic benefits associated with pneumococcal vaccination of elderly persons with chronic lung disease. Arch Intern Med 159: 2437-2442
65. Nichol KL, Margolis KL, Wuorenma J (1994) The efficacy and cost effectiveness of vaccination against influenza among elderly persons living in the community. N Engl J Med 331: 778-784