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Volumn 13, Issue 5, 2003, Pages 823-827

Site-directed mutagenesis on putative macrolactone ring size determinant in the hybrid pikromycin-tylosin polyketide synthase

Author keywords

Domain skipping; Pikromycin tylosin; Polyketide; Polyketide synthase

Indexed keywords

PIKROMYCIN; POLYKETIDE SYNTHASE; TYLOSIN;

EID: 0242720400     PISSN: 10177825     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (9)

References (16)
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    • The hidden steps of domain skipping: Macrolactone ring size determination in the pikromycin modular polyketide synthase
    • Beck, B. J., Y. J. Yoon, K. A. Renolds, and D. H. Sherman. 2002. The hidden steps of domain skipping: Macrolactone ring size determination in the pikromycin modular polyketide synthase. Chem. Biol. 9: 575-583.
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    • Beck, B.J.1    Yoon, Y.J.2    Renolds, K.A.3    Sherman, D.H.4
  • 2
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    • Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp
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  • 3
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    • Mechanisms of molecular recognition in the pikromycin polyketide synthase
    • Chen, S., Y. Xue, D. H. Sherman, and K. A. Reynolds. 2000. Mechanisms of molecular recognition in the pikromycin polyketide synthase. Chem. Biol. 7: 907-918.
    • (2000) Chem. Biol. , vol.7 , pp. 907-918
    • Chen, S.1    Xue, Y.2    Sherman, D.H.3    Reynolds, K.A.4
  • 4
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    • Identification of Streptomyces sp. producing new polyene antibiotics and in vivo antimicrobial activity of Tetrin C against phytopathogenic fungi
    • Choi, W. C., S. Y. Hwang, T. K. Park, and S. K. Kim. 2002. Identification of Streptomyces sp. producing new polyene antibiotics and in vivo antimicrobial activity of Tetrin C against phytopathogenic fungi. J. Microbiol. Biotechnol. 12: 199-204.
    • (2002) J. Microbiol. Biotechnol. , vol.12 , pp. 199-204
    • Choi, W.C.1    Hwang, S.Y.2    Park, T.K.3    Kim, S.K.4
  • 5
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    • Premature release of polyketide intermediates by hybrid polyketide synthase in Amycolatopsis mediterranei S699
    • Hong, J. S. J., C. Y. Choi, and Y. J. Yoon. 2003. Premature release of polyketide intermediates by hybrid polyketide synthase in Amycolatopsis mediterranei S699. J. Microbiol. Biotechnol. 13: 613-619.
    • (2003) J. Microbiol. Biotechnol. , vol.13 , pp. 613-619
    • Hong, J.S.J.1    Choi, C.Y.2    Yoon, Y.J.3
  • 6
    • 0029797581 scopus 로고    scopus 로고
    • Evidence for two catalytically independent clusters of active sites in a functional modular polyketide synthase
    • Kao, C. M., R. Pieper, D. E. Cane, and C. Khosla. 1996. Evidence for two catalytically independent clusters of active sites in a functional modular polyketide synthase. Biochemistry 35: 12363-12368.
    • (1996) Biochemistry , vol.35 , pp. 12363-12368
    • Kao, C.M.1    Pieper, R.2    Cane, D.E.3    Khosla, C.4
  • 9
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    • Purification and characterization of biomodular and trimodular derivatives of the erythromycin polyketide synthase
    • Pieper R., R. S. Gokhale, G. Luo, D. E. Cane, and C. Khosla. 1997. Purification and characterization of biomodular and trimodular derivatives of the erythromycin polyketide synthase. Biochemistry 36: 1846-1851.
    • (1997) Biochemistry , vol.36 , pp. 1846-1851
    • Pieper, R.1    Gokhale, R.S.2    Luo, G.3    Cane, D.E.4    Khosla, C.5
  • 13
    • 0034598743 scopus 로고    scopus 로고
    • Alternative modular polyketide synthase expression controls macrolactone structure
    • Xue, Y. and D. H. Sherman. 2000. Alternative modular polyketide synthase expression controls macrolactone structure. Nature 403: 571-575.
    • (2000) Nature , vol.403 , pp. 571-575
    • Xue, Y.1    Sherman, D.H.2
  • 14
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    • Genetic architecture of the polyketide synthases for methymycin and pikromycin series macrolides
    • Xue, Y., D. Wilson, and D. H. Sherman. 2000. Genetic architecture of the polyketide synthases for methymycin and pikromycin series macrolides. Gene 245: 203-211.
    • (2000) Gene , vol.245 , pp. 203-211
    • Xue, Y.1    Wilson, D.2    Sherman, D.H.3
  • 15
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    • A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: Architecture of metabolic diversity
    • Xue, Y., L. Zhao, H. W. Liu, and D. H. Sherman. 1998. A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: Architecture of metabolic diversity. Proc. Natl. Acad. Sci. USA 95: 12111-12116.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12111-12116
    • Xue, Y.1    Zhao, L.2    Liu, H.W.3    Sherman, D.H.4
  • 16
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    • Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae
    • Yoon, Y. J., B. J. Beck, B. S. Kim, H. Y. Kang, K. A. Reynolds, and D. H. Sherman. 2002. Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae. Chem. Biol. 9: 203-214.
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    • Yoon, Y.J.1    Beck, B.J.2    Kim, B.S.3    Kang, H.Y.4    Reynolds, K.A.5    Sherman, D.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.