Higher Gastric Cycloxygenase-2 Expression and Precancerous Change in Helicobacter pylori-Infected Relatives of Gastric Cancer Patients

Clinical Cancer Research

Volumn 9, Issue 14, 2003, Pages 5245-5251

  Sheu, Bor Shyang ^a,b   Yang, Hsiao Bai ^a   Sheu, Shew Meei ^a   Huang, Ay Huey ^a   Wu, Jiunn Jong ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; CLARITHROMYCIN; CYCLOOXYGENASE 2; OMEPRAZOLE;

ADULT; ARTICLE; ATROPHY; CANCER INCIDENCE; CONTROLLED STUDY; DUODENUM ULCER; ENDOSCOPY; ERADICATION THERAPY; FEMALE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; IMMUNOCHEMISTRY; INTESTINE METAPLASIA; MAJOR CLINICAL STUDY; MALE; PRECANCER; PREVALENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RELATIVE; STOMACH CANCER;

ADULT; CYCLOOXYGENASE 2; DUODENAL ULCER; ENDOSCOPY; FEMALE; GASTRIC MUCOSA; GASTRITIS, ATROPHIC; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INTESTINAL NEOPLASMS; ISOENZYMES; MALE; MEMBRANE PROTEINS; PRECANCEROUS CONDITIONS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; STOMACH NEOPLASMS;

EID: 0242610407     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Parsonnet, J., Friedman, G. D., Vandersteen, D. P., Chang, Y., Vogelman, J. H., Orentreich, N., and Sibley, R. K. Helicobacter pylori infection and the risk of gastric carcinoma. N. Engl. J. Med., 325: 1127-1131, 1991.
2. Asaka, M., Takeda, H., Sugiyama, T., and Kato, M. What role does Helicobacter pylori play in gastric cancer? Gastroenterology, 113: S56-S60, 1997.
3. Watanabe, T., Tada, M., Nagai, H., Sasaki, S., and Nakao, M. Helicobacter pylori infection induces gastric cancer in Mongoliam gerbils. Gastroenterology, 115: 642-648, 1998.
4. Honda, S., Fujioka, T., Tokieda, M., Satoh, R., Nishizono, A., and Nasu, M. Development of Helicobacter pylori-induced gastric carcinoma in Mongolian gerbils. Cancer Res., 58: 4255-4259, 1998.
5. Brenner, H., Bode, G., and Boeing, H. Helicobacterpylori infection among the offspring of patients with stomach cancer. Gastroenterology, 118: 31-35, 2000.
6. La Vecchia, C., Negri, E., Franceschi, S., and Gentile, A. Family history and the risk of stomach and colorectal cancer. Cancer (Phila.), 70: 50-55, 1992.
7. Huang, J. G., Sridhar, S., Chen, Y., and Hunt, R. H. Meta-analysis of the relationship between Helicobacter pylori seropositivity and gastric cancer. Gastroenterology, 114: 1169-1179, 1998.
8. El-Omar, E. M., Chow, W. H., and Rabkin, C. M. Gastric cancer and H. pylori: Host genetics open the way. Gastroenterology, 121: 1002-1004, 2001.
9. El-Omar, E. M., Oien, K., Murray, L. S., El-Nujumi, A., Wirz, A., Gillen, D., Williams, C., Fullarton, G., and McColl, K. E. Increased prevalence of precancerous changes in relatives of gastric cancer patients: critical role of H. pylori. Gastroenterology, 118: 22-30, 2000.
10. Parsonnet, J. When heredity is infectious. Gastroenterology, 18: 222-224, 2000.
11. Lim, H. Y., Joo, H. J., Choi, J. H., Yi, J. W., Yang, M. S., Cho, D. Y., Kim, H. S., Nam, D. K., Lee, K. B., and Kim, H. C. Increased expression of cyclooxygenase-2 protein in human gastric carcinoma. Clin. Cancer Res., 6: 519-525, 2000.
12. Jackson, L. M., Wu, K. C., Mahida, Y. R., Jenkins, D., and Hawkey, C. J. Cyclooxygenase (COX) 1 and 2 in normal, inflamed, and ulcerated human gastric mucosa. Gut, 47: 762-770, 2000.
13. Tatsuguchi, A., Sakamoto, C., Wada, K., Akamatsu, T., Tsukui, T., Miyake, K., Futagami, S., Kishida, T., Fukuda, Y., Yamanaka, N., and Kobayashi, M. Localisation of cyclooxygenase 1 and cyclooxygenase 2 in Helicobacter pylori related gastritis and gastric ulcer tissues in humans. Gut, 46: 782-789, 2000.
14. Sung, J. J., Leung, W. K., Go, M. Y., To, K. F., Cheng, A. S., Ng, E. K., and Chan, F. K. Cyclooxygenase-2 expression in Helicobacter pylori-associated premalignant and malignant gastric lesions. Am. J. Pathol., 157: 729-735, 2000.
15. Yang, S. B., Sheu, B. S., Su, I. J., Chien, C. H., and Lin, X. Z. Clinical application of gastric histology to monitor treatment of dual therapy in H. pylori eradication. Dig. Dis. Sci., 42: 1835-1840, 1997.
16. Sheu, S. M., Sheu, B. S., Yang, H. B., Lai, C., Chu, T. C., and Wu, J. J. The presence of iceA1 but not cagA, cagC, cagE, cagF, cagN, cagT, or orf13 genes of Helicobacter pylor is associated with a more severe gastric inflammation in Taiwanese. J. Formos. Med. Assoc., 101: 18-23, 2002.
17. 13C-urea breath test is mandatory to detect H. pylori infection in patients after proton pump inhibitor-based triple therapy. Dig. Dis. Sci., 45: 1330-1336, 2000.
18. Dixon, M. F., Genta, R. M., Yardley, J. H., and Correa, P. Classification and grading of gastritis: the updated Sydney system. International Workshop on the Histology of Gastritis, Houston. Am. J. Surg. Pathol., 20: 1161-1181, 1994.
19. El-Omar, E. M. The importance of interleukin-1 β in Helicobacter pylori-associated disease. Gut, 48: 743-747, 2001.
20. El-Omar, E. M., Chow, W. H., Gammon, M. D., Vaughan, T. L., Risch, H. A., and Fraumeni, J. F., Jr. Proinflammatory genotypes of 1L-1β, TNF-a and IL-10 increase risk of distal gastric cancer but not of cardia or esophageal carcinoma. Gastroenterology, 120 (Suppl. 1): A86, 2001.
21. El-Omar, E. M., Carrington, M., Chow, W. H., McColl, K. E., Bream, J. H., Young, H. A., Herrera, J., Lissowska, J., Yuan, C. C., Rothman, N., Lanyon, G., Martin, M., Fraumeni, J. F., Jr., and Rabkin, C. S. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature (Lond.), 404: 398-402, 2000.
22. Barrios-Rodiles, M., Tiraloche, G., and Chadee, K. Lipopolysaccharide modulates cyclooxygenase-2 transcriptionally and posttranscriptionally in human macrophages independently from endogenous IL-1 β and TNF-α. J. Immunol., 163: 963-969, 1999.
23. Sung, J. J., Lin, S. R., Ching, J. Y., Zhou, L. Y., To, K. F., Wang, R. T., Leung, W. K., Ng, E. K., Lau, J. Y., Lee, Y. T., Yeung, C. K., Chao, W., and Chung, S. C. Atrophy and intestinal metaplasia one year after cure of H. pylori infection: a prospective, randomized study. Gastroenterology, 119: 7-14, 2000.