Betacellulin promotes growth of the gastrointestinal organs and effects a diuresis in normal rats

Growth Factors

Volumn 21, Issue 2, 2003, Pages 79-86

  Howarth, Gordon S ^a,b,c   Bastian, Susan E P ^a,d   Dunbar, Andrew J ^a,d   Goddard, Chris ^a,e  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^c UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^d CSIRO   (Australia)

^e GroPep Ltd   (Australia)

Author keywords

Betacellulin; Growth; Infusion; Intestine; Rats

Indexed keywords

BETACELLULIN; BROXURIDINE; EPIDERMAL GROWTH FACTOR; INSULIN;

ANIMAL TISSUE; ARTICLE; ASCENDING COLON; BODY WEIGHT; CELL PROLIFERATION; CONTROLLED STUDY; CRYPT CELL; DESCENDING COLON; DIURESIS; DOSE RESPONSE; DRUG BLOOD LEVEL; FOOD INTAKE; GASTROINTESTINAL TRACT; HOMEOSTASIS; ILEUM; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; JEJUNUM; MALE; NONHUMAN; ORGAN GROWTH; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD GLUCOSE; DIGESTIVE SYSTEM; DIURESIS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; ORGAN SIZE; PERSONAL SPACE; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; TIME FACTORS;

ANIMALIA;

EID: 0242551563     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.1080/08977190310001605779     Document Type: Article

References (42)

1. Barnard, J.A., Graves-Deal, R., et al. (1994) "Auto- and cross-induction within the mammalian epidermal growth factor-related peptide family", J. Biol. Chem. 269(36), 22817-22822.
2. 3IGF-I in pregnant rats", J. Endocrinol. 138, 327-336.
3. Bastian, S.E., Dunbar, A.J., et al. (2001) "Measurement of betacellulin levels in bovine serum, colostrum and milk", J. Endocrinol. 168(1), 203-212.
4. Berlanga-Acosta, J., Playford, R.J., et al. (2001) "Gastrointestinal cell proliferation and crypt fission are separate but complementary means of increasing tissue mass following infusion of epidermal growth factor in rats", Gut 48(6), 803-807.
5. Blikslager, A.T., Rhoads, J.M., et al. (1999) "Glutamine and transforming growth factor-alpha stimulate extracellular regulated kinases and enhance recovery of villous surface area in porcine ischemic-injured intestine", Surgery 125, 186-194.
6. Buret, A., Olson, M.E., et al. (1998) "Effects of orally administered epidermal growth factor on enteropathogenic Escherichia coli infection in rabbits", Infect. Immun. 66(10), 4917-4923.
7. Danielsen, A.J. and Maihle, N.J. (2002) "The EGF/ErbB receptor family and apoptosis", Growth Factors 20(1), 1-15.
8. De Fazio, A., Leary, J.A., et al. (1987) "Immunohistochemical detection of proliferating cells in vivo", J. Histochem. Cytochem. 35, 571-577.
9. Drucker, D.J., De Forest, L. and Brubaker, P.L. (1997) "Intestinal response to growth factors administered alone or in combination with human [Gly2]glucagon-like peptide 2", Am. J. Physiol. 273(6 Pt 1), G1252-G1262.
10. Dunbar, A.J. and Goddard, C. (2000) "Structure-function and biological role of betacellulin", Int. J. Biochem. Cell Biol. 32(8), 805-815.
11. Dunbar, A.J., Priebe, I.K., et al. (1999) "Identification of betacellulin as a major peptide growth factor in milk: purification, characterization and molecular cloning of bovine betacellulin", Biochem. J. 344(Pt 3), 713-721.
12. Dunbar, A.J., Priebe, I.K., et al. (2001) "Purification and molecular characterization of recombinant rat betacellulin", J. Mol. Endocrinol. 27(2), 239-247.
13. Egger, B., Carey, H.V., et al. (1998) "Reduced susceptibility of mice overexpressing transforming growth factor alpha to dextran sodium sulphate induced colitis", Gut. 43, 64-70.
14. Erwin, C.R., Helmrath, M.A., et al. (1999) "Intestinal overexpression of EGF in transgenic mice enhances adaptation after small bowel resection", Am. J. Physiol. 277, G533-G540.
15. Gow, C.B. and Phillips, P.A. (1994) "Epidermal growth factor as a diuretic in sheep", J. Physiol. 477(Pt 1), 27-33.
16. Grant, S.L., Gow, C.B. and Phillips, P.A. (1997) "Epidermal growth factor and fluid and electrolyte balance in the rat", Am. J. Physiol. 272(6Pt 2), R1853-RI861.
17. Howarth, G.S., Xian, C.J. and Read, L.C. (2000) "Predisposition to colonic dysplasia is unaffected by continuous administration of insulin-like growth factor-I for twenty weeks in a rat model of chronic inflammatory bowel disease", Growth Factors 18, 119-133.
18. Huotari, M.A., Palgi, J. and Otonkosk, T. (1998) "Growth factor-mediated proliferation and differentiation of insulin-producing INS-1 and RINm5F cells: identification of betacellulin as a novel beta-cell mitogen", Endocrinology 139(4), 1494-1499.
19. Kallincos, N.C., Xian, C.J., et al. (2000) "Cloning of rat betacellulin and characterization of its expression in the gastrointestinal tract", Growth Factors 18(3), 203-213.
20. Karnes, W.E. Jr. (1994) "Epidermal growth factor and transforming growth factor-α", In: Walsh, J.H. and Dockray, G.J., eds, Gut Peptides: Biochemistry and Physiology (Raven, New York), pp. 553-586.
21. Li, L., Seno, M., et al. (2001) "Promotion of beta-cell regeneration by betacellulin in ninety percent-pancreatectomized rats", Endocrinology 142(12), 5379-5385.
22. Luck, M.S. and Bass, P. (1993) "Effect of epidermal growth factor on experimental colitis in the rat", J. Pharmacol. Exp. Ther. 264(2), 984-990.
23. Mashima, H., Ohnishi, H., et al. (1996) "Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells", J. Clin. Invest. 97(7), 1647-1654.
24. Miyagawa, J., Hanafusa, O., et al. (1999) "Immunohistochemical localization of betacellulin, a new member of the EGF family, in normal human pancreas and islet tumor cells", Endocr. J. 46(6), 755-764.
25. Modjtahedi, H. and Dean, C. (1996) "Monoclonal antibodies to the EGF receptor act as betacellulin antagonists", Biochem. Biophys. Res. Commun. 221(3), 625-630.
26. Phillips, P.A., Grant, S.L., et al. (1994) "Epidermal growth factor antagonizes vasopressin in vivo and in vitro", Kidney Int. 45(4), 1028-1036.
27. Pillai, S.B., Hinman, C.E., et al. (1999) "Heparin-binding epidermal growth factor-like growth factor protects rat intestine from ischemia/reperfusion injury", J. Surg. Res. 87, 225-231.
28. Plata-Salaman, C.R. (1988) "Food intake suppression by growth factors and platelet peptides by direct action in the central nervous system", Neurosci. Lett. 94(1-2), 161-166.
29. Procaccino, F., Reinshagen, M., et al. (1994) "Protective effect of epidermal growth factor in an experimental model of colitis in rats", Gastroenterology 107(1), 12-17.
30. Ribbons, K.A., Howarth, G.S., et al. (1994) "Subcutaneous but not intraluminal epidermal growth factor stimulates colonic growth in normal adult rats", Growth Factors 10(3), 153-162,
31. Sasada, R. and Igarashi, K. (1993) "Betacellulin: a new growth factor for vascular smooth muscle cells", Nippon Rinsho. 51(12), 3308-3317.
32. Sasada, R., Ono, Y., et al. (1993) "Cloning and expression of cDNA encoding human betacellulin, a new member of the EGF family", Biochem. Biophys. Res. Commun. 190(3), 1173-1179.
33. Seno, M., Tada, H., et al. (1996) "Human betacellulin, a member of the EGF family dominantly expressed in pancreas and small intestine, is fully active in a monomeric form", Growth Factors 13(3-4), 181-191.
34. Shing, Y., Christofori, G., et al. (1993) "Betacellulin: a mitogen from pancreatic beta cell tumors", Science 259(5101), 1604-1607.
35. Shinohara, H., Williams, C.S., et al. (2001) "Transforming growth factor-alpha delays gastric emptying and small intestinal transit in suckling rats", Scand. J. Gastroenterol. 36(4), 356-360.
36. Tada, H., Sasada, R., et al. (1999) "Processing and juxtacrine activity of membrane-anchored betacellulin", J. Cell Biochem. 72(3), 423-434.
37. Tada, H., Seno, M., et al. (2000) "Molecular cloning and expression of rat betacellulin cDNA", Biochim. Biophys. Acta 1492(1 , 285-288.
38. Tomas, F.M., Knowles, S.E. and Owens, P.C. (1991) "Effects of full-length and truncated insulin-like growth factor-I on nitrogen balance and muscle protein metabolism in nitrogen-restricted rats", J. Endocrinol. 128(1), 97-105.
39. Wright, N.A., Pike, C. and Elia, G. (1990) "Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells", Nature 343, 82-85.
40. Yamamoto, K., Miyagawa, J., et al. (2000) "Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion", Diabetes 49(12), 2021-2027.
41. Yoshida, S., Kajimoto, Y., et al. (2002) "PDX-1 induces differentiation of intestinal epithelioid IEC-6 into insulin-producing cells", Diabetes 51(8), 2505-2513.
42. Zijlstra, R.T., Odle, J., et al. (1994) "Effect of orally administered epidermal growth factor on intestinal recovery of neonatal pigs infected with rotavirus", Pediatr. Gastroenterol. Nutr. 19(4), 382-390.