Development of a Genetic Algorithm to Design and Identify Peptides that can Cross the Blood-Brain Barrier: 1. Design and validation in silico

QSAR and Combinatorial Science

Volumn 22, Issue 7, 2003, Pages 745-753

  Teixidó, Meritxell ^a   Belda, Ignasi ^a   Roselló, Xavier ^b   González, Sonia ^a   Fabre, Myriam ^a   Llorá, Xavier ^d   Bacardit, Jaume ^c   Garrell, Josep M ^c   Vilaró, Senen ^a   Albericio, Fernando ^a   Giralt, Ernest ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITAT POLITÈCNICA DE CATALUNYA   (Spain)

^c UNIVERSITAT RAMON LLULL   (Spain)

^d Ramon Llull University ^*

Author keywords

ADME properties; Blood Brain Barrier; Genetic Algorithm; Peptide Transport

Indexed keywords

BLOOD; CHELATION; DIAGNOSIS; DIGITAL LIBRARIES; PEPTIDES;

ADME PROPERTY; BLOOD-BRAIN BARRIER; CENTRAL NERVOUS SYSTEMS; COMPUTER-AIDED; IN-SILICO; LIGAND DESIGN; PEPTIDE DRUGS; PEPTIDE LIBRARY; PEPTIDE TRANSPORT; PROPERTY;

GENETIC ALGORITHMS;

PEPTIDE LIBRARY;

ARTICLE; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM DISEASE; COMPUTER AIDED DESIGN; DRUG DESIGN; GENETIC ALGORITHM; PRIORITY JOURNAL; PROTEIN TRANSPORT; STATISTICAL ANALYSIS;

EID: 0242551208     PISSN: 1611020X     EISSN: None     Source Type: Journal    
DOI: 10.1002/qsar.200320004     Document Type: Article

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