Gene Testing: What the Health Professional Needs to Know

Journal of Nutrition

Volumn 133, Issue 11 SUPPL. 1, 2003, Pages

  Keku, Temitope O ^a,b   Rakhra Burris, Tejinder ^b   Millikan, Robert ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b University of North Carolina at Chapel Hill   (United States)

Author keywords

DNA; Genetic counseling; Genetic testing; Health professionals

Indexed keywords

APC PROTEIN; BRCA1 PROTEIN; BRCA2 PROTEIN; DNA; PROTEIN RET; RNA; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRASTUZUMAB;

BREAST TUMOR; CLINICAL RESEARCH; COLON POLYPOSIS; COLORECTAL CANCER; CONFERENCE PAPER; CYSTIC FIBROSIS; DECISION MAKING; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC ANALYSIS; GENETIC COUNSELING; GENETIC DISORDER; GENETIC SUSCEPTIBILITY; HEALTH CARE PERSONNEL; HUMAN; HUMAN GENOME; MULTIPLE ENDOCRINE NEOPLASIA; NEUROFIBROMATOSIS; OVARY CANCER; PATIENT CARE; PHYSICIAN; POLYMERASE CHAIN REACTION; SICKLE CELL ANEMIA; SOCIAL PSYCHOLOGY; THYROID CANCER;

EID: 0242526063     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/133.11.3754s     Document Type: Conference Paper

References (25)

1. Glazier, A. M., Nadeau, J. H. & Aitman, T. J. (2002) Finding genes that underlie complex traits. Science 298: 2345-2349.
2. Grady, W. M. (2003) Genetic testing for high risk colon cancer patients. Gastroenterology 124: 1574-1594.
3. Holtzman, N. A. & Watson, M. S. (1999) Promoting safe and effective genetic tests in the United States: work of the task force on genetic testing. Clin. Chem. 45: 732-738.
4. Pergament, E. (2000) New molecular techniques for chromosome analysis. Ballieres Best Pract. Res. Clin. Obstet. Gynaecol. 14: 677-690.
5. Children's Health System and University of Washington. Seattle. Gene tests. Available at http://www.genetests.org (accessed July 20, 2003).
6. Weisner, G. L. & Snow-Bailey, K. Multiple endocrine neoplasia type 2 [MEN 2A (sipple syndrome), MEN 2B (mucosal neuroma syndrome), familial medullary thyroid carcinoma (FMTC)]). Available at http://www.geneclinics.org/profiles/men2/details.html (accessed July 5, 2003).
7. Burke, W. (2002) Genetic testing. N. Engl. J. Med. 347: 1867-1875.
8. Weitzel, J. N. (1999) Genetic cancer risk assessment. Cancer 86 (Suppl): 2483-2492.
9. Hadley, D. W., Jenkins, J., Diamond, E., Nakahara, K., Grogan, L., Liewehr, D. J., Steinberg, S. M. & Kirsch, I. (2003) Genetic counseling and testing in families with hereditary nonpolyposis colorectal cancer. Arch. Intern. Med. 163: 573-582.
10. Hahn, M., Saeger, H. D. & Schackert, H. D. (1999) Hereditary colorectal cancer: clinical consequences of predictive molecular testing. Int. J. Colorectal Dis. 14: 184-193.
11. Higashi, M. K., Veenstra, D. L., Kondo, L. M., Wittkowsky, A. K., Srinouanprachanh, S. L., Farin, F. M. & Rettie, A. E. (2002) Association of between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. J. Am. Med. Assoc. 287: 1690-1691.
12. Aithal, G. P., Day, C. P., Kesteven, P. J. & Daly, A. K. (1999) Association of polymorphisms in the cytochrome P450 CYP2C9 variant. Lancet 353: 717-719.
13. Ensenauer, R. E., Reinke, S. S., Ackerman, M. J., Tester, D. J., Whiteman, D. A. & Tefferi, A. (2003) Primer on medical genomics. Part VIII: Essentials of medical genetics for the practicing physician. Mayo Clin. Proc. 78: 846-857.
14. American Society of Clinical Oncology. (1996) Statement of the American Society of Clinical Oncology, genetic testing for cancer susceptibility, adopted on February 20, 1996. J. Clin. Oncol. 14: 1730-1740.
15. Wideroff, L., Freedman, A. N., Olson, L., Klabunde, C. N., Davis, W., Srinath, K. P., Croyle, R. T. & Ballard-Barbash, R. (2003) Physician's use of genetic testing for cancer susceptibility: results of a national survey. Cancer Epidemiol. Biomarkers Prev. 12: 295-303.
16. Giardiello, F. M., Brensinger, J. D., Petersen, G. M., Luce, M. C., Hylind, L. M., Bacon, J. A., Booker, S. V., Parker, R. D. & Hamilton, S. R. (1997) The use and interpretation of commercial APC gene testing for familial adenomatous polyposis. N. Engl. J. Med. 336: 823-827.
17. Friedman, L. C., Plon, S. E., Cooper, H. P. & Weinberg, A. D. (1997) Cancer genetics survey primary care physicians and attitudes. J. Cancer Educ. 12: 199-203.
18. Goel, V. (2001) Appraising organized screening programmes for testing for genetic susceptibility to cancer. BMJ 322: 1174-1178.
19. Holtzman, N. A. (1999) Promoting safe and effective genetic tests in the United States: work of the task force on genetic testing. Clin. Chem. 45: 732-738.
20. Snow, K. (2001) The growing impact of genetics on health care: do we have appropriate educational resources? Mayo Clin. Proc. 76: 769-771.
21. Pagon, R. A., Pinsky, L. & Beahler, C. C. (2001) Online medical genetics resources: a US perspective. BMJ 322: 1035-1037.
22. Tarczy-Hornoch, P., Shannon, P., Baskin, P., Espeseth, M. & Pagon, R. A. (2000) GeneClinics: a hybrid text/data electronic publishing model using XML applied to clinical genetic testing. J. Am. Med. Inform. Assoc. 7: 267-276.
23. Hopwood, P. (1997) Psychological issues in cancer genetics: current research and future priorities. Patient Educ. Couns. 32: 19-31.
24. Bleiker, E. M. A., Aaronson, N. K., Menko, F. H., Hahn, D. E., van Asperen, C. J., Rutgers, E. J., ten Kate, L. P. & Leschot, N. J. (1997) Genetic counseling for hereditary cancer: a pilot study on experiences for patients and family members. Patient Educ. Couns. 32: 107-116.
25. Salkovskis, P. M., Dennis, R. & Wroe, A. L. (1999) An experimental study of influences on the perceived likelihood of seeking genetic testing. J. Psychosom. Res. 47: 439-447.