Selective toxicity of engineered lentivirus lytic peptides in a CF airway cell model

Peptides

Volumn 24, Issue 8, 2003, Pages 1099-1107

  Phadke, Shruti M ^a   Islam, Kazi ^b   Deslouches, Berthony ^b   Kapoor, Sunil A ^c   Stolz, Donna Beer ^b   Watkins, Simon C ^b   Montelaro, Ronald C ^b   Pilewski, Joseph M ^b,d   Mietzner, Timothy A ^b  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b Dept of Molec Genet/Biochemistry ^*  (United States)

^c Pediatric Lung Center   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Airway epithelial cells; Antimicrobial peptide; Cystic fibrosis; Selective toxicity

Indexed keywords

ANTIINFECTIVE AGENT; ARGINYLTRYPTOPHYLISOLEUCYLARGINYLVALYLVALYLGLUTAMINYLARGINYLTRYPTOPHYLCYSTE INYLARGINYLALANYLISOLEUCYLARGINYLHISTIDYLISOLEUCYLTRYPTOPHYLARGINYLARGINYLISOLEU CYLARGINYLGLUTAMINYLGLYCYLLEUCYLARGINYLARGINYLTRYPTOPHYLLEUCYLARGINYLVALYLVALINE; ARGINYLVALYLISOLEUCYLARGINYLVALYLVALYLGLUTAMINYLARGINYLALANYLCYSTEINYLARGIN YLALANYLISOLEUCYLARGINYLHISTIDYLISOLEUCYLVALYLARGINYLARGINYLISOLEUCYLARGINYLGLUT AMINYLGLYCYLLEUCYLARGINYLARGINYLISOLEUCYLLEUCINE; ARGINYLVALYLISOLEUCYLARGINYLVALYLVALYLGLUTAMINYLARGINYLALANYLCYSTEINYLARGIN YLALANYLISOLEUCYLARGINYLHISTIDYLISOLEUCYLVALYLARGINYLARGINYLISOLEUCYLARGINYLGLUT AMINYLGLYCYLLEUCYLARGINYLARGINYLISOLEUCYLLEUCYLARGINYLVALYLVALINE; ARGINYLVALYLISOLEUCYLGLUTAMYLVALYLVALYLGLUTAMINYLGLYCYLALANYLCYSTEINYLARGIN YLALANYLISOLEUCYLARGINYLHISTIDYLISOLEUCYLPROLYLARGINYLARGINYLISOLEUCYLARGINYLGLU TAMINYLGLYCYLLEUCYLGLUTAMYLARGINYLISOLEUCYLLEUCINE; SODIUM CHLORIDE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANTIBACTERIAL ACTIVITY; APOPTOSIS; ARTICLE; BACTERICIDAL ACTIVITY; CELL VIABILITY; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LENTIVIRINAE; LUNG ALVEOLUS CELL; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

HUMAN IMMUNODEFICIENCY VIRUS 1; LENTIVIRUS; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0242495095     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2003.07.001     Document Type: Article

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