Direct evidence for expression of Type II flavoprotein subunit in human complex II (succinate-ubiquinone reductase)

Biochemical and Biophysical Research Communications

Volumn 311, Issue 3, 2003, Pages 774-779

  Tomitsuka, Eriko ^a   Goto, Yu Ichi ^b   Taniwaki, Masafumi ^c   Kita, Kiyoshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^c KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Complex II; Flavoprotein subunit; Human mitochondria; Isoforms; Succinate ubiquinone reductase

Indexed keywords

FLAVOPROTEIN; ISOENZYME; MITOCHONDRIAL ENZYME; PROTEIN SUBUNIT; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUCROSE LAURATE;

ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME ISOLATION; ENZYME SUBUNIT; HUMAN; HUMAN CELL; ISOELECTRIC FOCUSING; LIVER MITOCHONDRION; MITOCHONDRION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAJI CELL; SEPARATION TECHNIQUE;

EID: 0242493177     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.10.065     Document Type: Article

References (26)

1. Lancaster C.R.D. Special issue for complex II. Biochim. Biophys. Acta. 1553:2002;1-176.
2. Ohnishi T., Christopher C.M., Christopher C.P., Dutton P.L., Yano Y. Simple redox-linked proton-transfer design: new insights from structures of quinol-fumarate reductase. Struct. Fold. Des. 8:2000;R23-R32.
3. Kita K., Hirawake H., Miyadera H., Amino H., Takeo S. Role of complex II in anaerobic respiration of the parasite mitochondria from Ascaris suum and Plasmodium falciparum. Biochim. Biophys. Acta. 1553:2002;123-139.
4. Weinberg J.M., Venkatachalam M.A., Roeser N.F., Nissim I. Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediate. Proc. Natl. Acad. Sci. USA. 97:2000;2826-2831.
5. Paddenberg R., Ishaq B., Goldenberg A., Faulhammer P., Rose F., Weissmann N., Braun-Dullaeus R.C., Kummer W. Essential role of complex II of the respiratory chain in hypoxia-induced ROS generation in the pulmonary vasculature. Am. J. Physiol., Lung Cell. Mol. Physiol. 284:2003;L710-L719.
6. Rivner H.H., Shamsnia M., Swift T.R., Trefz J., Roesel R.A., Carter A.L., Yanamura W., Hommes F.A. Kearns-Sayre syndrome and complex II deficiency. Neurology. 39:1989;693-696.
7. Riggs J.E., Schochet S.S. Jr., Fakadej A.V., Papadimitriou A., DiMauro S., Crosby T.W., Gutmann L., Moxley R.T. Mitochondrial encephalomyopathy with decreased succinate-cytochrome. c reductase activity Neurology. 34:1984;48-53.
8. Rustin P., LeBidois J., Chrtien D., Bourgeron T., Piechaud J.F., Rotig A., Sidi D., Munnich A. The investigation of respiratory chain disorders in heart using endomyocardial biopsies. J. Inherit. Metab. Dis. 16:1993;541-544.
9. Reichmann H., Angelini C. Single muscle fibre analyses in 2 brothers with succinate dehydrogenase deficiency. Eur. Neurol. 34:1994;95-98.
10. Sugimoto J., Shimohira M., Osawa Y., Matsubara M., Yamamoto H., Goto Y., Nonaka I. A patient with mitochondrial myopathy associated with isolated succinate dehydrogenase deficiency. Brain Dev. 22:2000;158-162.
11. Taylor R.W., Birch-Machin M.A., Schaefer J., Taylor L., Shakir R., Ackrell B.A., Cochran B., Bindoff L.A., Jackson M.J., Griffiths P., Turnbull D.M. Deficiency of complex II of the mitochondrial respiratory chain in late-onset optic atrophy and ataxia. Ann. Neurol. 39:1996;224-232.
12. Bourgeron T., Rustin P., Chretien D., Birch-Machin M., Bourgeois M., Viegas-Pequignot E., Munnich A., Rotig A. Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency. Nat. Genet. 11:1995;144-148.
13. Parfait B., Chretien D., Rotig A., Marsac C., Muunich A., Rustin P. Compound heterozygous mutations in the flavoprotein gene of the respiratory chain complex II in a patient with Leigh syndrome. Hum. Genet. 106:2000;236-243.
14. Eng C., Kiuru M., Fernandez M.J., Aaltonen L.A. A role for mitochondrial enzymes in inherited neoplasia and beyond. Nat. Rev. 3:2003;193-202.
15. Baysal B.E. Hereditary paraganglioma targets diverse palaganglia. J. Med. Genet. 39:2002;617-622.
16. Maher E.R., Eng C. The pressure rises: update on the genetics of phaeochromocytoma. Hum. Mol. Genet. 11:2002;2347-2354.
17. Tomitsuka E., Hirawake H., Goto Y., Taniwaki M., Harada S., Kita K. Direct evidence for two distinct forms of the flavoprotein subunit of human mitochondrial complex II (succinate-ubiquinone reductase). J. Biochem. 134:2003;191-195.
18. Kler R.S., Jackson S., Bartlett K., Bindoff L.A., Eaton S., Pourfarzan M., Frerman F.E., Goodman S.I., Watmough N.J., Turnbull D.M. Quantitation of Acyl-CoA and acylcarnitine esters accumulated during abnormal mitochondria fatty acid oxidation. J. Biol. Chem. 266:1991;22932-22938.
19. 556 J. Biol. Chem. 264:1989;2672-2677.
20. Schulenberg B., Aggeler R., Beechem J.M., Capaldi R.A., Patton W.F. Analysis of steady-state protein phosphorylation in mitochondria using a novel fluorescent phosphosensor dye. J. Biol. Chem. 278:2003;27251-27255.
21. Johnson N.O-. Direct and indirect inhibitor of mitochondrial ATP synthesis. Methods Cell. Biol. 65:2001;483-493.
22. Miyadera H., Shiomi K., Ui H., Yamaguchi Y., Masuma R., Tomoda H., Miyoshi H., Osanai A., Kita K., Omura S. Apenins, potent and specific inhibitor of mitochondrial complex II (succinate-ubiquinone oxidoreductase). Proc. Natl. Acad. Sci. USA. 100:2003;473-477.
23. Ackrell B.A.C. Progress in understanding structure-function relationships in respiratory chain complex II. FEBS Lett. 466:2000;1-5.
24. Kita K., Nihei C., Tomitsuka E. Parasite mitochondria as drug target: diversity and dynamic changes during the life cycle. Curr. Med. Chem. 10:2003;1241-1253.
25. Hirawake H., Taniwaki M., Tamura A., Amino H., Tomitsuka E., Kita K. Characterization of the human SDHD gene encoding the small subunit of cytochrome. b (cybS) in mitochondrial succinate-ubiquinone oxidoreductase Biochem. Bioophys. Acta. 1412:1999;295-300.
26. Birch-Machin M.A., Marsac C., Ponsot G., Parfait B., Taylor R.W., Rustin P., Munnich A. Biochemical investigations and immunoblot analysis of two unrelated patients with an isolated deficiency in complex II of the mitochondrial respiratory chain. Biochem. Biophys. Res. Commun. 220:1996;57-62.