Alterations in the expression of cytochrome c oxidase subunits in doxorubicin-resistant leukemia K562 cells

Biochemical Pharmacology

Volumn 63, Issue 5, 2002, Pages 823-831

  Grandjean, Fabienne ^a,b   Brémaud, Laure ^b   Robert, Jacques ^c   Ratinaud, Marie Hélène ^a  

^a CNRS   (France)

^b UNIVERSITY OF LIMOGES   (France)

^c INSTITUT BERGONIÉ   (France)

Author keywords

Cytochrome c oxidase; Doxorubicin (adriamycin); Mitochondria; Multidrug resistance

Indexed keywords

CYTOCHROME C OXIDASE; DOXORUBICIN; MESSENGER RNA;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBUNIT; HUMAN; HUMAN CELL; LEUKEMIA; MITOCHONDRION; MULTIDRUG RESISTANCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CATALYSIS; DNA, MITOCHONDRIAL; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ELECTRON TRANSPORT COMPLEX IV; GENE EXPRESSION; HUMANS; K562 CELLS; LEUKEMIA; RNA, MESSENGER;

EID: 0036496854     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00865-6     Document Type: Article

References (46)

1. Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II
2. Transcriptional down-regulation of c-myc expression in an erythroleukemic cell line, K562, and its doxorubicin-resistant variant by two topoisomerase II inhibitors, doxorubicin and amsacrine
3. The anticancer agent adriamycin can be actively cytotoxic without entering cells
4. Redox cycling of anthracyclines by cardiac mitochondria. Part II. Formation of superoxide anion, hydrogen peroxide and hydroxyl radical
5. Enhancement of reactive oxygen-dependent mitochondrial lipid peroxidation by the anticancer drug adriamycin
6. Subcellular effects of adriamycin in the heart: A concise review
7. Adriamycin inactivates cytochrome c oxidase by exclusion of the enzyme from its cardiolipin essential environment
8. Interaction of adriamycin with negatively charged model membranes: Evidence of two types of binding sites
9. Adriamycin as a probe for the transversal distribution of cardiolipin in the inner mitochondrial membrane
10. Evidence of a complex between adriamycin derivatives and cardiolipin: Possible role in cardiotoxicity
11. Anthracycline glycoside-membrane interactions
12. The biochemistry of P-glycoprotein-mediated multidrug resistance
13. Modifications of oxido-reductase activities in adriamycin-resistant K562 cells
14. Separation of mammalian cytochrome c oxidase into 13 polypeptides by a sodium dodecyl sulfate-gel electrophoretic procedure
15. Structure and function of cytochrome c oxidase
16. Human cytochrome c oxidase: Structure, function and deficiency
17. Sequence and organization of the human mitochondrial genome
18. L expression in a leukemia cell line and its doxorubicin-resistant variant by topoisomerase II inhibitors
19. Human chronic myelogenous leukemia cell line with positive Philadelphia chromosome
20. Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones
21. Sequential gene expression of P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP) and lung resistance protein (LRP): Functional activity of P-gp and MRP present in the doxorubicin-resistant human K562 cell lines
22. Isolation and characterization of mitochondria from human B lymphoblastoid cell lines
23. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
24. Cleavage of structural proteins during assembly of head of bacteriophage T4
25. DNA sequencing with chain-terminating inhibitors
26. Real time quantitative PCR
27. Structural comparison of anticancer drug-DNA complexes: Adriamycin and daunomycin
28. A deletion of mitochondrial DNA in murine doxorubicin-induced cardiotoxicity
29. Altered processing of precursor transcripts and increased levels of the subunit I of mitochondrial cytochrome c oxidase in Syrian hamster fetal cells initiated with ionizing radiation
30. Mitochondrial myopathies: Genetic aspects
31. Nuclear gene products required for translation of specific mitochondrially-coded mRNA in yeast
32. Control of mitochondrial gene expression in Saccharomyces cerevisiae
33. Mechanism of mRNA binding to bovine mitochondrial ribosomes
34. Interaction of bovine mitochondrial ribosomes with messenger RNA
35. The tRNA punctuation model of RNA processing in human mitochondria
36. Initiation of transcription from each of the two human mitochondrial promoters requires unique nucleotide at the transcriptional start site
37. A pathogenic 15-base pair deletion in mitochondrial DNA-encoded cytochrome c oxidase subunit III results in the absence of functional cytochrome c oxidase
38. An antisense oligodeoxynucleotide approach to investigate the function of the nuclear-encoded subunits of human cytochrome c oxidase
39. Deletion of the COX7 gene in Saccharomyces cerevisiae reveals a role for cytochrome c oxidase subunit VII in assembly of remaining subunits
40. Regulation of cytochrome c oxidase by interaction of ATP at two binding sites, one on subunit VIa
41. Selective removal of subunit VIb increases the activity of cytochrome c oxidase
42. Nuclear respiratory factors and the pathways of nuclear-mitochondrial interaction
43. The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease
44. Three-dimensional structures of cytochrome c oxidase vesicle crystals in negative stain