메뉴 건너뛰기




Volumn 54, Issue 11, 2003, Pages 1073-1079

Proteolytic enzymes in wound-bed preparation of chronic wounds;Konditionierung chronischer wunden mittels proteolytischer enzyme

Author keywords

Chronic wounds; Proteolytic enzymes; Wound bed preparation; Wound healing

Indexed keywords

BROMELAIN; CATALASE; CLOSTRIDIOPEPTIDASE A; COLLAGENASE; DEOXYRIBONUCLEASE; PAPAIN; PLASMIN; PROTEINASE; STREPTODORNASE; STREPTOKINASE; SUTILAIN; TRYPSIN;

EID: 0242437918     PISSN: 00178470     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00105-003-0582-6     Document Type: Review
Times cited : (4)

References (56)
  • 1
    • 0037244670 scopus 로고    scopus 로고
    • Severely impaired wound healing in the collagenase-resistant mouse
    • Beare AH, O'Kane S, Krane SM, Ferguson MW (2003) Severely impaired wound healing in the collagenase-resistant mouse. J Invest Dermatol 120:153-163
    • (2003) J Invest Dermatol , vol.120 , pp. 153-163
    • Beare, A.H.1    O'Kane, S.2    Krane, S.M.3    Ferguson, M.W.4
  • 3
    • 0007779059 scopus 로고
    • The hidden powers of pineapple
    • Bicherstaff CR (1988) The hidden powers of pineapple. New Sci 118:46-48
    • (1988) New Sci , vol.118 , pp. 46-48
    • Bicherstaff, C.R.1
  • 4
    • 0032886236 scopus 로고    scopus 로고
    • The debridement of chronic wounds: A systematic review
    • Bradley M, Cullum N, Sheldon T (1999) The debridement of chronic wounds: a systematic review. Health Technol Assess 3:1-78
    • (1999) Health Technol Assess , vol.3 , pp. 1-78
    • Bradley, M.1    Cullum, N.2    Sheldon, T.3
  • 5
    • 0036834937 scopus 로고    scopus 로고
    • Ultraviolet-B irradiation and matrix metalloproteinases: From induction via signaling to initial events
    • Brenneisen P, Sies H, Scharffetter-Kochanek K (2002) Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events. Ann N Y Acad Sci 973:31-43
    • (2002) Ann N Y Acad Sci , vol.973 , pp. 31-43
    • Brenneisen, P.1    Sies, H.2    Scharffetter-Kochanek, K.3
  • 6
    • 0036246719 scopus 로고    scopus 로고
    • Mechanism of action of PROMOGRAN, a protease modulating matrix, for the treatment of diabetic foot ulcers
    • Cullen B, Smith R, McCulloch E et al. (2002) Mechanism of action of PROMOGRAN, a protease modulating matrix, for the treatment of diabetic foot ulcers. Wound Repair Regen 10:16-25
    • (2002) Wound Repair Regen , vol.10 , pp. 16-25
    • Cullen, B.1    Smith, R.2    McCulloch, E.3
  • 7
    • 0036935979 scopus 로고    scopus 로고
    • Die Bedeutung von oxidativem Streβ in der Genese und Therapie chronischer Wunden
    • Dissemond J, Goos M, Wagner SN (2002) Die Bedeutung von oxidativem Streβ in der Genese und Therapie chronischer Wunden. Hautarzt 53:718-723
    • (2002) Hautarzt , vol.53 , pp. 718-723
    • Dissemond, J.1    Goos, M.2    Wagner, S.N.3
  • 9
    • 0242400513 scopus 로고    scopus 로고
    • Untersuchungen zum pH-Wert des Milieus chronischer Wunden im Rahmen einer modernen Wundtherapie
    • in press
    • Dissemond J, Witthoff M, Brauns TC, Goos M (in press) Untersuchungen zum pH-Wert des Milieus chronischer Wunden im Rahmen einer modernen Wundtherapie. Hautarzt
    • Hautarzt
    • Dissemond, J.1    Witthoff, M.2    Brauns, T.C.3    Goos, M.4
  • 10
    • 0002438273 scopus 로고    scopus 로고
    • Surgical debridement versus enzymatic debridement - Benefits and drawbacks
    • Baharestani M, Gottrrup F, Holstein P, Vanscheidt (eds). Springer, Berlin Heidelberg New York Tokyo
    • Dräger E, Winter H (1999) Surgical debridement versus enzymatic debridement-benefits and drawbacks. In: Baharestani M, Gottrrup F, Holstein P, Vanscheidt (eds) The clinical relevance of debridement. Springer, Berlin Heidelberg New York Tokyo, pp 59-70
    • (1999) The Clinical Relevance of Debridement , pp. 59-70
    • Dräger, E.1    Winter, H.2
  • 11
    • 0035068587 scopus 로고    scopus 로고
    • Modified cotton gauze dressings that selectively absorb neutrophil elastase activity in solution
    • Edwards JV, Yager DR, Cohen IK et al.(2001) Modified cotton gauze dressings that selectively absorb neutrophil elastase activity in solution. Wound Repair Regen 2001 9:50-58
    • (2001) Wound Repair Regen 2001 , vol.9 , pp. 50-58
    • Edwards, J.V.1    Yager, D.R.2    Cohen, I.K.3
  • 13
    • 0242567864 scopus 로고    scopus 로고
    • Evaluation of the activity of high-dose collagenase in an experimental model of burn wound in the rat
    • Baharestani M, Gottrrup F, Holstein P, Vanscheidt (eds). Springer, Berlin Heidelberg New York Tokyo
    • Eloy R, Charton-Picard F, Vaudable I et al.(1999) Evaluation of the activity of high-dose collagenase in an experimental model of burn wound in the rat. In: Baharestani M, Gottrrup F, Holstein P, Vanscheidt (eds) The clinical relevance of debridement. Springer, Berlin Heidelberg New York Tokyo, pp 31-44
    • (1999) The Clinical Relevance of Debridement , pp. 31-44
    • Eloy, R.1    Charton-Picard, F.2    Vaudable, I.3
  • 14
    • 0036440651 scopus 로고    scopus 로고
    • Treatment of chronic wound: State of the art and future concepts
    • Eming SA, Smola H, Krieg T (2002) Treatment of chronic wound: state of the art and future concepts. Cell Tissue Organs 172:105-117
    • (2002) Cell Tissue Organs , vol.172 , pp. 105-117
    • Eming, S.A.1    Smola, H.2    Krieg, T.3
  • 15
    • 0031797939 scopus 로고    scopus 로고
    • The safety and efficacy of a proteolytic ointment in the treatment of chronic ulcers of the lower extremity
    • Falabella AF, Carson P, Eaglstein WH, Falanga V (1998) The safety and efficacy of a proteolytic ointment in the treatment of chronic ulcers of the lower extremity. J Am Acad Dermatol 39:737-740
    • (1998) J Am Acad Dermatol , vol.39 , pp. 737-740
    • Falabella, A.F.1    Carson, P.2    Eaglstein, W.H.3    Falanga, V.4
  • 16
    • 0242567867 scopus 로고    scopus 로고
    • The safety and efficacy of a proteolytic ointment in the treatment of chronic ulcers of the lower extremity
    • Falabella AF, Carson P, Eaglstein WH, Falanga V (2000) The safety and efficacy of a proteolytic ointment in the treatment of chronic ulcers of the lower extremity. J Wound Care 9:223-226
    • (2000) J Wound Care , vol.9 , pp. 223-226
    • Falabella, A.F.1    Carson, P.2    Eaglstein, W.H.3    Falanga, V.4
  • 17
    • 0027990415 scopus 로고
    • Wound repair in the context of extracellular matrix
    • Gailit J, Clark RAF (1994) Wound repair in the context of extracellular matrix. Curr Opin Cell Biol 6:717-725
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 717-725
    • Gailit, J.1    Clark, R.A.F.2
  • 18
    • 0036946879 scopus 로고    scopus 로고
    • Modernes Wundmangement
    • Gillitzer R (2002) Modernes Wundmangement. Hautarzt 53:130-147
    • (2002) Hautarzt , vol.53 , pp. 130-147
    • Gillitzer, R.1
  • 20
    • 0015773566 scopus 로고
    • Sutilains ointment as a topical debriding agent in burns
    • Grossman AR (1973) Sutilains ointment as a topical debriding agent in burns. Int Surg 58:93-96
    • (1973) Int Surg , vol.58 , pp. 93-96
    • Grossman, A.R.1
  • 21
    • 0035487891 scopus 로고    scopus 로고
    • Proteolytic degradation of oral biofilms in vitro and in vivo: Potential of proteases originated from euphausia superba for plaque control
    • Hahn Ber IC, Kalfas S et al.(2001) Proteolytic degradation of oral biofilms in vitro and in vivo: potential of proteases originated from euphausia superba for plaque control. Eur J Oral Sci 109:316-324
    • (2001) Eur J Oral Sci , vol.109 , pp. 316-324
    • Hahn Ber, I.C.1    Kalfas, S.2
  • 23
    • 0036635809 scopus 로고    scopus 로고
    • Inflammation. 2: Its role in the healing of chronic wounds
    • Hart J (2002) Inflammation. 2: Its role in the healing of chronic wounds. J Wound Care 11:245-249
    • (2002) J Wound Care , vol.11 , pp. 245-249
    • Hart, J.1
  • 24
    • 0024227185 scopus 로고
    • Wundheilungsstörungen und ihre enzymatische Therapie-eine mutizentrische Doppelblindstudie
    • Helaly P, Vogt E, Schneider G (1988) Wundheilungsstörungen und ihre enzymatische Therapie-eine mutizentrische Doppelblindstudie. Schweiz Rundschau Med 52:1428-1434
    • (1988) Schweiz Rundschau Med , vol.52 , pp. 1428-1434
    • Helaly, P.1    Vogt, E.2    Schneider, G.3
  • 25
    • 0022442261 scopus 로고
    • Proteases of Antarctic krill - A new system for effective enzymatic debridement of necrotic ulcerations
    • Hellgren L, Mohr V, Vincent J (1986) Proteases of Antarctic krill - a new system for effective enzymatic debridement of necrotic ulcerations. Experientia 42:403-404
    • (1986) Experientia , vol.42 , pp. 403-404
    • Hellgren, L.1    Mohr, V.2    Vincent, J.3
  • 26
    • 0035204586 scopus 로고    scopus 로고
    • Matrix metalloproteinases in skin pathology
    • Herouy Y (2001) Matrix metalloproteinases in skin pathology. Int J Mol Med 7:3-12
    • (2001) Int J Mol Med , vol.7 , pp. 3-12
    • Herouy, Y.1
  • 27
    • 0031968707 scopus 로고    scopus 로고
    • Consideration for the use of clostridial Collagenase in clinical practice
    • Jung W, Winter H (1998) Consideration for the use of clostridial Collagenase in clinical practice. Clin Drug Invest 15:24S-252
    • (1998) Clin Drug Invest , vol.15
    • Jung, W.1    Winter, H.2
  • 28
    • 0019946709 scopus 로고
    • Collagenases and collagen degradation
    • Krane SM (1982) Collagenases and collagen degradation. J Invest Dermatol 79:83-86
    • (1982) J Invest Dermatol , vol.79 , pp. 83-86
    • Krane, S.M.1
  • 29
    • 0034075954 scopus 로고    scopus 로고
    • Propeptide dependent activation of the antartic krill euphauserase precursor produced in yeast
    • Kristjansdottir S, Gudmundsdottir A (2000) Propeptide dependent activation of the antartic krill euphauserase precursor produced in yeast. Eur J Biochem 267:2632-2639
    • (2000) Eur J Biochem , vol.267 , pp. 2632-2639
    • Kristjansdottir, S.1    Gudmundsdottir, A.2
  • 30
    • 0027212247 scopus 로고
    • Enzymatic debridement of leg ulcers using papain
    • Laidet B, Letoumeur M (1993) Enzymatic debridement of leg ulcers using papain. Ann Dermatol Venereol 120:248
    • (1993) Ann Dermatol Venereol , vol.120 , pp. 248
    • Laidet, B.1    Letoumeur, M.2
  • 31
    • 0034843751 scopus 로고    scopus 로고
    • Bromelain: Biochemistry, pharmacology and medical use
    • Maurer HR (2001) Bromelain: biochemistry, pharmacology and medical use. Cell Mol Life Sci 58:1234-1245
    • (2001) Cell Mol Life Sci , vol.58 , pp. 1234-1245
    • Maurer, H.R.1
  • 32
    • 0031598623 scopus 로고    scopus 로고
    • Efficient debridement of necrotic wounds using proteolytic enzymes derived from Antarctic krill: A double-blind, placebo-controlled study in a standardized animal wound model
    • Mekkes JR, Le Poole IC, Das PK et al. (1998) Efficient debridement of necrotic wounds using proteolytic enzymes derived from Antarctic krill: a double-blind, placebo-controlled study in a standardized animal wound model. Wound Repair Regen 6:50-57
    • (1998) Wound Repair Regen , vol.6 , pp. 50-57
    • Mekkes, J.R.1    Le Poole, I.C.2    Das, P.K.3
  • 33
    • 0242652317 scopus 로고    scopus 로고
    • Collagenase in a new formulation accelerates wound cleaning and wound healing
    • Baharestani M, Gottrrup F, Holstein P, Vanscheidt (eds). Springer, Berlin Heidelberg New York Tokyo
    • Mekkes JR, Zeegelaar JE (1999) Collagenase in a new formulation accelerates wound cleaning and wound healing. In: Baharestani M, Gottrrup F, Holstein P, Vanscheidt (eds) The clinical relevance of debridement. Springer, Berlin Heidelberg New York Tokyo, pp 45-58
    • (1999) The Clinical Relevance of Debridement , pp. 45-58
    • Mekkes, J.R.1    Zeegelaar, J.E.2
  • 34
    • 0031915249 scopus 로고    scopus 로고
    • Quantitative and objective evaluation of wound debriding properties of collagenase and fibrinolysin/desoxyribonuclease in a necrotic ulcer animal model
    • Mekkes JR, Zeegelaar JE, Westerhof W (1998) Quantitative and objective evaluation of wound debriding properties of collagenase and fibrinolysin/desoxyribonuclease in a necrotic ulcer animal model. Arch Dermatol Res 290:152-157
    • (1998) Arch Dermatol Res , vol.290 , pp. 152-157
    • Mekkes, J.R.1    Zeegelaar, J.E.2    Westerhof, W.3
  • 35
    • 0018602679 scopus 로고
    • Debridement of burns with proteolytic enzymes from Bacillus subtilis
    • Muller FE (1979) Debridement of burns with proteolytic enzymes from Bacillus subtilis. Z Plast Chir 3:197-206
    • (1979) Z Plast Chir , vol.3 , pp. 197-206
    • Muller, F.E.1
  • 36
    • 0033953104 scopus 로고    scopus 로고
    • Effect of Varidase (streptokinase) on biofilm formed by Staphylococcus aureus
    • Nemoto K, Hirota K, Ono T et al. (2000) Effect of Varidase (streptokinase) on biofilm formed by Staphylococcus aureus. Chemotherapy 46:111-115
    • (2000) Chemotherapy , vol.46 , pp. 111-115
    • Nemoto, K.1    Hirota, K.2    Ono, T.3
  • 37
    • 0031801061 scopus 로고    scopus 로고
    • Iruxol mono ointment in the treatment of ulcers of the lower extremities. A placebo-controlled, double-blind study
    • Palmieri B, Magri M (1998) Iruxol mono ointment in the treatment of ulcers of the lower extremities. A placebo-controlled, double-blind study. Clin Drug Invest 15:381-387
    • (1998) Clin Drug Invest , vol.15 , pp. 381-387
    • Palmieri, B.1    Magri, M.2
  • 38
    • 0036230424 scopus 로고    scopus 로고
    • The effect of wound ointments on tissue microcirculation and leucocyte behaviour
    • Peter FW, Li-Peuser H, Vogt PM et al. (2002) The effect of wound ointments on tissue microcirculation and leucocyte behaviour. Clin Exp Dermatol 27:51-55
    • (2002) Clin Exp Dermatol , vol.27 , pp. 51-55
    • Peter, F.W.1    Li-Peuser, H.2    Vogt, P.M.3
  • 39
    • 85012405294 scopus 로고
    • Collagen- and collagen peptide induced chemotaxis of human blood monocytes
    • Postlewaite AE, Kang AH (1976) Collagen- and collagen peptide induced chemotaxis of human blood monocytes. J Exp Med 143:1299-1307
    • (1976) J Exp Med , vol.143 , pp. 1299-1307
    • Postlewaite, A.E.1    Kang, A.H.2
  • 40
    • 0036231973 scopus 로고    scopus 로고
    • Prospective randomized double-blind study of the wound-debriding effects of collagenase and fibrinolysin/deoxyribonuclease in pressure ulcers
    • Pullen R, Popp R, Volkers P, Fusgen I (2002) Prospective randomized double-blind study of the wound-debriding effects of collagenase and fibrinolysin/deoxyribonuclease in pressure ulcers. Age Ageing 31:126-130
    • (2002) Age Ageing , vol.31 , pp. 126-130
    • Pullen, R.1    Popp, R.2    Volkers, P.3    Fusgen, I.4
  • 41
    • 0036231973 scopus 로고    scopus 로고
    • Prospective randomized double-blind studey of the wound-debriding effects of collagenase and fibrinolysin/deoxyribonuclease in pressure ulcers
    • Pullen R, Popp R, Volkers P, Fusgen I (2002) Prospective randomized double-blind studey of the wound-debriding effects of collagenase and fibrinolysin/deoxyribonuclease in pressure ulcers. Age Ageing 31:126-130
    • (2002) Age Ageing , vol.31 , pp. 126-130
    • Pullen, R.1    Popp, R.2    Volkers, P.3    Fusgen, I.4
  • 43
    • 0027403114 scopus 로고
    • Potent debriding ability of collagenolytic protease isolated from the hepatopancreas of the king crab Paralithodes camtschatica
    • Sakharov IY, Glyanzev SP, Litvin FE, Sawina TV (1993) Potent debriding ability of collagenolytic protease isolated from the hepatopancreas of the king crab Paralithodes camtschatica. Arch Dermatol Res 285:32-35
    • (1993) Arch Dermatol Res , vol.285 , pp. 32-35
    • Sakharov, I.Y.1    Glyanzev, S.P.2    Litvin, F.E.3    Sawina, T.V.4
  • 46
    • 0035701613 scopus 로고    scopus 로고
    • Differential proteinase expression by Pseudomonas aeruginosa derived from chronic leg ulcers
    • Schmidtchen A, Wolff H, Hansson C (2001) Differential proteinase expression by Pseudomonas aeruginosa derived from chronic leg ulcers. Acta Derm Venereol 81:406-409
    • (2001) Acta Derm Venereol , vol.81 , pp. 406-409
    • Schmidtchen, A.1    Wolff, H.2    Hansson, C.3
  • 47
    • 0019520949 scopus 로고
    • Wound cleansing with the enzyme combination fibrinolysin/deoxy-ribonuclease
    • Schwarz N (1981) Wound cleansing with the enzyme combination fibrinolysin/deoxy-ribonuclease. Fortschr Med 99:978-980
    • (1981) Fortschr Med , vol.99 , pp. 978-980
    • Schwarz, N.1
  • 48
    • 0015831646 scopus 로고
    • Use of water insoluble papain for debridement of burn eschar and necrotic tissue
    • Shapira E, Giladi A, Neiman Z (1973) Use of water insoluble papain for debridement of burn eschar and necrotic tissue. Plast Reconstruct Surg 52:279
    • (1973) Plast Reconstruct Surg , vol.52 , pp. 279
    • Shapira, E.1    Giladi, A.2    Neiman, Z.3
  • 50
    • 0002384649 scopus 로고
    • Types of chronic wounds: Indications for enzymatic debridement
    • Westerhof W, Vanscheidt W (eds). Springer, Berlin Heidelberg New York Tokyo
    • Sinclair RD, Ryan TJ (1994) Types of chronic wounds: indications for enzymatic debridement. In: Westerhof W, Vanscheidt W (eds) Proteolytic enzymes and wound healing. Springer, Berlin Heidelberg New York Tokyo, pp 7-20
    • (1994) Proteolytic Enzymes and Wound Healing , pp. 7-20
    • Sinclair, R.D.1    Ryan, T.J.2
  • 51
    • 0036418040 scopus 로고    scopus 로고
    • Characterization of proteinases from Antarctic krill (Euphausia superba)
    • Sjodahl J, Emmer A, Vincent J, Roeraade J (2002) Characterization of proteinases from Antarctic krill (Euphausia superba). Protein Expr Purif 26:153-161
    • (2002) Protein Expr Purif , vol.26 , pp. 153-161
    • Sjodahl, J.1    Emmer, A.2    Vincent, J.3    Roeraade, J.4
  • 52
    • 0021094244 scopus 로고
    • Enzymatic debridement of wounds. Comparison of 2 commercial preparations
    • Stuwe U (1983) Enzymatic debridement of wounds. Comparison of 2 commercial preparations. Fortschr Med 101:1883-1888
    • (1983) Fortschr Med , vol.101 , pp. 1883-1888
    • Stuwe, U.1
  • 53
    • 0033155763 scopus 로고    scopus 로고
    • The identification and treatment of slough
    • Tong A (1999) The identification and treatment of slough. J Wound Care 8:338-339
    • (1999) J Wound Care , vol.8 , pp. 338-339
    • Tong, A.1
  • 54
    • 0007969778 scopus 로고    scopus 로고
    • Randomised study on the efficacy of a collagenase-containing ointment versus hydrocolloid dressing in wound repair after surgical/enzymario debridement of necrotic tissue
    • Baharestani M, Gottrrup F, Holstein P, Vanscheidt (eds). Springer, Berlin Heidelberg New York Tokyo
    • Van Leen MWF (1999) Randomised study on the efficacy of a collagenase-containing ointment versus hydrocolloid dressing in wound repair after surgical/enzymario debridement of necrotic tissue. In: Baharestani M, Gottrrup F, Holstein P, Vanscheidt (eds)The clinical relevante of debridement. Springer, Berlin Heidelberg New York Tokyo, pp 71-80
    • (1999) The Clinical Relevante of Debridement , pp. 71-80
    • Van Leen, M.W.F.1
  • 55
    • 0034987641 scopus 로고    scopus 로고
    • Selective pick-up of increased iron by deferoxamine-coupled cellulose abrogates the iron-driven induction of matrix-degrading metalloproteinase-1 and lipid peroxidation in human dermal fibroblasts in vitro - A new dressing concept
    • Wenk J, Foitzik A, Achterberg V et al. (2001) Selective pick-up of increased iron by deferoxamine-coupled cellulose abrogates the iron-driven induction of matrix-degrading metalloproteinase-1 and lipid peroxidation in human dermal fibroblasts in vitro - a new dressing concept, J Invest Dermatol 116:833-839
    • (2001) J Invest Dermatol , vol.116 , pp. 833-839
    • Wenk, J.1    Foitzik, A.2    Achterberg, V.3
  • 56
    • 0025226155 scopus 로고
    • Prospective randomized study comparing the debriding effect of krill enzymes and a non-enzymatic treatment in venous leg ulcers
    • Westerhof W, van Ginkel CJ, Cohen EB, Mekkes JR (1990) Prospective randomized study comparing the debriding effect of krill enzymes and a non-enzymatic treatment in venous leg ulcers. Dermatologica 181:293-297
    • (1990) Dermatologica , vol.181 , pp. 293-297
    • Westerhof, W.1    Van Ginkel, C.J.2    Cohen, E.B.3    Mekkes, J.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.