Organolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines

Tetrahedron

Volumn 59, Issue 49, 2003, Pages 9729-9742

  Hodgson, David M ^a   Miles, Timothy J ^a   Witherington, Jason ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b Glaxo Smith Kline   (United Kingdom)

Author keywords

Amino alcohols; Eliminations and alkenes; Epoxides; Organolithiums

Indexed keywords

1 (2 METHYLPROPANE 2 SULFONYL) 1,2,3,4 TETRAHYDROPYRIDIN 4 OL; 1 (2 METHYLPROPANE 2 SULFONYL) 2,5 DIHYDRO 1H PYRROLE; 2 METHYLPROPANE 2 SULFONIC ACID (2 HYDROXY 2 METHYL 3 METHYLENEHEPTYL)AMIDE; 2 METHYLPROPANE 2 SULFONIC ACID (2 HYDROXY 2 METHYL 3 PHENYLBUT 3 ENYL)AMIDE; 2 METHYLPROPANE 2 SULFONIC ACID (2 HYDROXY 3 METHYLENEHEPTYL)AMIDE; 2 METHYLPROPANE 2 SULFONIC ACID (2 HYDROXY 4 METHYL 3 METHYLENEHEXYL)AMINE; 2 METHYLPROPANE 2 SULFONIC ACID (2 HYDROXY 4 METHYL 3 METHYLENEPENTYL)AMIDE; 2 METHYLPROPANE 2 SULFONIC ACID (3 HYDROXY 4 METHYLENEOCTYL)AMIDE; 2 METHYLPROPANE 2 SULFONIC ACID DIALLYLAMIDE; 2 METHYLPROPANE 2 SULFONIC ACID [2 HYDROXY 2 METHYL 3 (TRIMETHYLSILYLMETHYL)BUT 3 ENYL]AMIDE; 3 (2 METHYLPROPANE 2 SULFONYL) 6 OXA 3 AZABICYCLO[3.1.0]HEXANE; 3 (2 METHYLPROPANE 2 SULFONYL) 7 OXA 3 AZABICYCLO[4.1.0]HEPTANE; ALCOHOL DERIVATIVE; AMIDE; AMINOALCOHOL; EPOXIDE; ORGANOLITHIUM COMPOUND; PYRIDINE DERIVATIVE; PYRROLE DERIVATIVE; TETRAHYDROPYRIDINOL; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RING OPENING; SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

EID: 0242391657     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2003.10.010     Document Type: Article

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