Induction of Tumor Necrosis Factor-α by UVB: A Role for Reactive Oxygen Intermediates and Eicosanoids

Photochemistry and Photobiology

Volumn 78, Issue 1, 2003, Pages 68-74

  Pupe, Annemie ^a   Degreef, Hugo ^a   Garmyn, Marjan ^a,b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b Department of Dermatology ^*  (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BUTYL HYDROPEROXIDE; BUTYLATED HYDROXYANISOLE; EPIGALLOCATECHIN GALLATE; ICOSANOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOMETACIN; LIPOXYGENASE INHIBITOR; MEPACRINE; MESSENGER RNA; NORDIHYDROGUAIARETIC ACID; PHOSPHOLIPASE A2; PROSTAGLANDIN SYNTHASE INHIBITOR; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

AEROBIC METABOLISM; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; KERATINOCYTE; ULTRAVIOLET B RADIATION;

ANTIOXIDANTS; CYCLOOXYGENASE INHIBITORS; EICOSANOIDS; FERROUS COMPOUNDS; HUMANS; HYDROGEN PEROXIDE; KERATINOCYTES; LIPOXYGENASE; NF-KAPPA B; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; ULTRAVIOLET RAYS;

EID: 0242302448     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/0031-8655(2003)078<0068:IOTNFB>2.0.CO;2     Document Type: Article

References (44)

1. Vink, A. A. and L. Roza (2001) Biological consequences of cyclobutane pyrimidine dimers. J. Photochem. Photobiol. B: Biol. 65, 101-104.
2. Tyrrell, R. M. (1995) Ultraviolet radiation and free radical damage to skin. Biochem. Soc. Symp. 61, 47-53.
3. Takashima, A. and P. R. Bergstresser (1996) Impact of UVB radiation on the epidermal cytokine network. Photochem. Photobiol. 63, 397-400.
4. Bazzoni, F. and B. Beutler (1996) The tumor necrosis factor ligand and receptor families. N. Engl. J. Med. 334, 1717-1725.
5. Kondo, S. and D. N. Sauder (1995) Keratinocyte-derived cytokines and UVB-induced immunosuppression. J. Dermatol. 22, 888-893.
6. Kock, A., T. Schwarz, R. Kirnbauer, A. Urbanski, P. Perry, J. C. Ansel and T. A. Luger (1990) Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light. J. Exp. Med. 172, 1609-1614.
7. Schwarz, A., R. Bhardwaj, Y. Aragane, K. Mahnke, H. Riemann, D. Metze, T. A. Luger and T. Schwarz (1995) Ultraviolet-B-induced apoptosis of keratinocytes: evidence for partial involvement of tumor necrosis factor-alpha in the formation of sunburn cells. J. Investig. Dermatol. 104, 922-927.
8. Simon, M. M., Y. Aragane, A. Schwarz, T. A. Luger and T. Schwarz (1994) UVB light induces nuclear factor kappa B (NF kappa B) activity independently from chromosomal DNA damage in cell-free cytosolic extracts. J. Investig. Dermatol. 102, 422-427.
9. Baeuerle, P. A. and D. Baltimore (1996) NF-kappa B: ten years after. Cell 87, 13-20.
10. Pupe, A., R. Moison, P. De Haes, V. H. Beijersbergen, L. Rhodes, H. Degreef and M. Garmyn (2002) Eicosapentaenoic acid, a n-3 polyunsaturated fatty acid differentially modulates TNF-alpha, IL-1alpha, IL-6 and PGE2 expression in UVB-irradiated human keratinocytes. J. Investig. Dermatol. 118, 692-698.
11. Corsini, E., A. Bruccoleri, M. Marinovich and C. L. Galli (1995) In vitro mechanism(s) of ultraviolet-induced tumor necrosis factor-alpha release in a human keratinocyte cell line. Photodermatol. Photoimmunol. Photomed. 11, 112-118.
12. Eugui, E. M., B. DeLustro, S. Rouhafza, M. Ilnicka, S. W. Lee, R. Wilhelm and A. C. Allison (1994) Some antioxidants inhibit, in a co-ordinate fashion, the production of tumor necrosis factor-alpha, IL-beta, and IL-6 by human peripheral blood mononuclear cells. Int. Immunol. 6, 409-422.
13. Dy, L. C., Y. Pei and J. B. Travers (1999) Augmentation of ultraviolet B radiation-induced tumor necrosis factor production by the epidermal platelet-activating factor receptor. J. Biol. Chem. 274, 26917-26921.
14. O'Connor, A., C. Nishigori, D. Yarosh, L. Alas, J. Kibitel, L. Burley, P. Cox, C. Bucana, S. Ullrich and M. Kripke (1996) DNA double strand breaks in epidermal cells cause immune suppression in vivo and cytokine production in vitro. J. Immunol. 157, 271-278.
15. Yarosh, D., D. Both, J. Kibitel, C. Anderson, C. Elmets, D. Brash and D. Brown (2000) Regulation of TNFalpha production and release in human and mouse keratinocytes and mouse skin after UV-B irradiation. Photodermatol. Photoimmunol. Photomed. 16, 263-270.
16. Cruz Jr., P. D., M. Leverkus, I. Dougherty, M. J. Gleason, M. Eller, M. Yaar and B. A. Gilchrest (2000) Thymidine dinucleotides inhibit contact hypersensitivity and activate the gene for tumor necrosis factor alpha1. J. Investig. Dermatol. 114, 253-258.
17. Kibitel, J., V. Hejmadi, L. Alas, A. O'Connor, B. M. Sutherland and D. Yarosh (1998) UV-DNA damage in mouse and human cells induces the expression of tumor necrosis factor alpha. Photochem. Photobiol. 67, 541-546.
18. Heller, A., T. Koch, J. Schmeck and K. van Ackern (1998) Lipid mediators in inflammatory disorders. Drugs 55, 487-496.
19. Chen, X., A. Gresham, A. Morrison and A. P. Pentland (1996) Oxidative stress mediates synthesis of cytosolic phospholipase A2 after UVB injury. Biochim. Biophys. Acta 1299, 23-33.
20. Isoherranen, K., K. Punnonen, C. Jansen and P. Uotila (1999) Ultraviolet irradiation induces cyclooxygenase-2 expression in keratinocytes. Br. J. Dermatol. 140, 1017-1022.
21. Roy, P., M. P. Sajan and A. P. Kulkarni (1995) Lipoxygenase-mediated glutathione oxidation and superoxide generation. J. Biochem. Toxicol. 10, 111-120.
22. Roy, P., S. K. Roy, A. Mitra and A. P. Kulkarni (1994) Superoxide generation by lipoxygenase in the presence of NADH and NADPH. Biochim. Biophys. Acta 1214, 171-179.
23. Punnonen, K., A. Puntala, C. T. Jansen and M. Ahotupa (1991) UVB irradiation induces lipid peroxidation and reduces antioxidant enzyme activities in human keratinocytes in vitro. Acta Dermato-Venereol. 71, 239-242.
24. Rice-Evans, C. (2001) Flavonoid antioxidants. Curr. Med. Chem. 8, 797-807.
25. Packer, L., S. U. Weber and G. Rimbach (2001) Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling. J. Nutr. 131, 369S-373S.
26. Ricciarelli, R., J. M. Zingg and A. Azzi (2001) Vitamin E: protective role of a Janus molecule. FASEB J. 15, 2314-2325.
27. Dixon, R. A., R. E. Diehl, E. Opas, E. Rands, P. J. Vickers, J. F. Evans, J. W. Gillard and D. K. Miller (1990) Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 343, 282-284.
28. Courtois, S. J., S. Segaert, H. Degreef, R. Bouillon and M. Garmyn (1998) Ultraviolet B suppresses vitamin D receptor gene expression in keratinocytes. Biochem. Biophys. Res. Commun. 246, 64-69.
29. Garmyn, M. and H. Degreef (1997) Suppression of UVB-induced c-fos and c-jun expression in human keratinocytes by N-acetylcysteine. J. Photochem. Photobiol. B: Biol. 37, 125-130.
30. Ahmad, N., S. Gupta and H. Mukhtar (2000) Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor kappa B in cancer cells versus normal cells. Arch. Biochem. Biophys. 376, 338-346.
31. Verhaegen, S., A. J. McGowan, A. R. Brophy, R. S. Fernandes and T. G. Cotter (1995) Inhibition of apoptosis by antioxidants in the human HL-60 leukemia cell line. Biochem. Pharmacol. 50, 1021-1029.
32. Timmins, G. S. and M. J. Davies (1993) Free radical formation in isolated murine keratinocytes treated with organic peroxides and its modulation by antioxidants. Carcinogenesis 14, 1615-1620.
33. Finstad, H. S., M. C. Wik Myhrstad, H. Heimli, J. Lomo, H. Kiil Blomhoff, S. O. Kolset and C. A. Drevon (1998) Multiplication and death-type of leukemia cell lines exposed to very long-chain polyunsaturated fatty acids. Leukemia 12, 921-929.
34. Straface, E., M. T. Santini, G. Donelli, P. U. Giacomoni and W. Malomi (1995) Vitamin E prevents UVB-induced cell blebbing and cell death in A431 epidermoid cells. Int. J. Radiat. Biol. 68, 579-587.
35. Shang, J., C. Schwarz, R. H. Sanchez, T. Hertting, C. E. Orfanos and B. Tebbe (2002) Effects of UVA and L-ascorbic acid on nuclear factor-kappa B in melanocytes and in HaCaT keratinocytes. Skin Pharmacol. Appl. Skin Physiol. 15, 353-359.
36. Savini, I., M. V. Catani, A. Rossi, G. Duranti, G. Melino and L. Avigliano (2002) Characterization of keratinocyte differentiation induced by ascorbic acid: protein kinase C involvement and vitamin C homeostasis. J. Investig. Dermatol. 118, 372-379.
37. Ogura, R., M. Sugiyama, J. Nishi and N. Haramaki (1991) Mechanism of lipid radical formation following exposure of epidermal homogenate to ultraviolet light. J. Investig. Dermatol. 97, 1044-1047.
38. Salari, H., P. Braquet and P. Borgeat (1984) Comparative effects of indomethacin, acetylenic acids, 15-HETE, nordihydroguaiaretic acid and BW755C on the metabolism of arachidonic acid in human leukocytes and platelets. Prostaglandins Leukot. Med. 13, 53-60.
39. Coutant, K. D., N. Corvaia and N. S. Ryder (1997) Bradykinin induces actin reorganization and enhances cell motility in HaCaT keratinocytes. Biochem. Biophys. Res. Commun. 237, 257-261.
40. Hulten, L. M., H. Lindmark, H. Schersten, O. Wiklund, F. N. Nilsson and G. C. Riise (1998) Butylated hydroxytoluene and N-acetylcysteine attenuates tumor necrosis factor-alpha (TNF-alpha) secretion and TNF-alpha mRNA expression in alveolar macrophages from human lung transplant recipients in vitro. Transplantation 66, 364-369.
41. Piette, J., B. Piret, G. Bonizzi, S. Schoonbroodt, M. P. Merville, S. Legrand-Poels and V. Bours (1997) Multiple redox regulation in NF-kappaB transcription factor activation. Biol. Chem. 378, 1237-1245.
42. Flohe, L., R. Brigelius-Flohe, C. Saliou, M. G. Traber and L. Packer (1997) Redox regulation of NF-kappa B activation. Free Radic. Biol. Med. 22, 1115-1126.
43. van Puijenbroek, A. A., S. Wissink, P. T. van der Saag and M. P. Peppelenbosch (1999) Phospholipase A2 inhibitors and leukotriene synthesis inhibitors block TNF-induced NF-kappa B activation. Cytokine 11, 104-110.
44. Slapke, J., T. Schewe, S. Hummel, J. Winkler and M. Kopf (1983) Lung strips from guinea pigs as test system for lipoxygenase inhibitors. Inhibition of arachidonic acid-induced contractions by 3-t-butyl-4-hydroxyanisole and nordihydroguaiaretic acid. Biomed. Biochim. Acta 42, 1309-1318.