MR Spectroscopy of Muscle and Brain in Guanidinoacetate Methyltransferase (GAMT)-Deficient Mice: Validation of an Animal Model to Study Creatine Deficiency

Magnetic Resonance in Medicine

Volumn 50, Issue 5, 2003, Pages 936-943

  Renema, W Klaas Jan ^a   Schmidt, Andreas ^b   Van Asten, Jack J A ^a   Oerlemans, Frank ^a   Ullrich, Kurt ^c   Wieringa, Bé ^a   Isbrandt, Dirk ^b   Heerschap, Arend ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Creatine; Energy metabolism; GAMT knockout; Magnetic resonance

Indexed keywords

CHROMIUM COMPOUNDS; MAGIC ANGLE SPINNING; MAGNETIC RESONANCE; MAGNETIC RESONANCE SPECTROSCOPY; MAMMALS; METABOLISM; SPECTRUM ANALYSIS;

CREATINE; ENERGY METABOLISM; FUNDAMENTAL STUDIES; GAMT-KNOCKOUT; HIGH RESOLUTION MAGIC ANGLE SPINNING; METHYLTRANSFERASES; MR SPECTROSCOPY; MUSCLE TISSUES;

MUSCLE;

GUANIDINOACETATE METHYLTRANSFERASE; GUANIDINOACETIC ACID; METHYLTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; CONTROLLED STUDY; CREATINE DEFICIENCY; DIAGNOSTIC PROCEDURE; ENERGY METABOLISM; HINDLIMB; IN VITRO STUDY; IN VIVO STUDY; INBORN ERROR OF METABOLISM; ISCHEMIA; KNOCKOUT GENE; KNOCKOUT MOUSE; LEG MUSCLE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; PROTON NUCLEAR MAGNETIC RESONANCE; VALIDATION PROCESS;

EID: 0242290992     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.10627     Document Type: Article

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