Expression of c-fos, p53 and PCNA in the unstable atherosclerotic carotid plaque

International Journal of Cardiology

Volumn 92, Issue 1, 2003, Pages 59-63

  Lavezzi, Anna Maria ^a   Milei, José ^a   Grana, Daniel R ^a   Flenda, Federica ^a   Basellini, Aldo ^a   Matturri, Luigi ^a  

^a NONE

Author keywords

Atherosclerosis; c fos; p53; PCNA; Unstable plaque

Indexed keywords

BIOLOGICAL MARKER; CYCLINE; ONCOPROTEIN; PROTEIN C FOS; PROTEIN P53;

ADULT; AGED; ARTICLE; ATHEROSCLEROTIC PLAQUE; CAROTID ENDARTERECTOMY; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; ONCOGENE C FOS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTO ONCOGENE; STROKE; SYMPTOMATOLOGY; TRANSIENT ISCHEMIC ATTACK;

EID: 0242289498     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5273(03)00055-X     Document Type: Article

References (24)

1. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 362:1993;801-809.
2. Mattturri L., Cazzullo A., Turconi P., Roncoroni L., Grana D., Milei J. Inflammatory cells, apoptosis and Chlamydia pneumoniae infection in atherosclerosis. Int J Cardiol. 75:2000;23-33.
3. Ross R., Glomset J.A. Atherosclerosis and the arterial smooth muscle cell. Science. 180:1973;1332-1339.
4. Ross R. Atherosclerosis: a defense mechanism gone. Am J Pathol. 143:1993;987-1002.
5. Fernández Alonso G., Grana D., Turconi P., et al. Actividad proliferativa y alteraciones cromosómicas de las células musculares lisas en la ateroesclerosis. Medicina (Bs Aires). 60:2000;595-601.
6. Martínez González J., Llorente Cortés V., Badimon L. Biología celular y molecular de las lesiones ateroescleróticas. Rev Esp Cardiol. 54:2001;218-231.
7. Milei J., Parodi J.C., Fernández Alonso G., Barone A., Grana D., Matturri L. Carotid rupture and intraplaque hemorrhage: immunophenotype and role of cells involved. Am Heart J. 136:1998;1096-1105.
8. Matturri L., Cazzullo A., Turconi P., et al. Chromosomal alterations in atherosclerotic plaques. Atherosclerosis. 154:2001;755-761.
9. Matturri L., Cazzullo A., Turconi P., Lavezzi A.M. Cytogenetic aspects of cell proliferation in atherosclerotic plaques. Cardiologia. 42:1997;833-836.
10. Herrera D.G., Robertson H.A. Activation of c-fos in the brain. Prog Neurobiol. 50:1996;83-107.
11. Hirooka Y., Polson J.W., Potts P.D., Dampney A.L. Hypoxia-induced Fos expression in neurons projecting to the pressor region in the rostral ventrolateral medulla. Neuroscience. 30:1997;1209-1224.
12. Sagar S.M., Sharp F.R., Curran T. Expression of c-fos protein in brain: metabolic mapping at the cellular level. Science. 240:1988;1328-1331.
13. Nogami M., Takatsu A., Endo N., Ishiyama I. Immunohistochemical localization of c-fos in the nuclei of the medulla oblongata in relation to asphyxia. Int J Legal Med. 112:1993;351-354.
14. Aoki M., Morishita R., Matsushita H., et al. Inhibition of the p53 tumor suppressor gene results in growth of human aortic vascular smooth muscle cells. Potential role of p53 in regulation of vascular smooth muscle cell growth. Hypertension. 34:1999;192-200.
15. Matturri L., Biondo B., Cazzullo A., et al. Detection of trisomy 7 with fluorescence in situ hybridization and its correlation with DNA content and PCNA positivity in prostate cancer. Am J Clin Oncol. 21:1998;253-257.
16. Fager G., Hansson G.K., Ottosson P., Dahllof B., Bondjers G. Human arterial smooth muscle cells in culture. Effects of platelet derived growth factor and heparin on growth in vitro. Exp Cell Res. 176:1988;319-335.
17. Nigro J.M., Baker S.J., Preisinger A.C., et al. Mutations in the p53 gene occur in diverse tumors types. Nature. 342:1989;705-708.
18. Levine A.J., Momand J., Finlay C.A. The p53 tumors suppressor gene. Nature. 351:1991;453-456.
19. Donehower L.A., Bradley A. The tumor suppressor p53. Acta Biochim Biophys. 1155:1993;181-205.
20. Dony C., Gruss P. Proto-oncogene c-fos expression in growth regions of fetal bone and mesodermal tissue. Nature. 299:1987;711-714.
21. Muchnok J.P., Klishis M.L., Roberts J.R., Antonini J.M., Whong W.Z., Ong T. Cadmium-induced cell transformation and tumorigenesis are associated with transcriptional activation of c-fos, c-jun and c-myc proto-oncogenes: role of cellular calcium and reactive oxygen species. Toxicol Sci. 61:2001;295-303.
22. Kee K.H., Lee M.U., Ro J.Y. Oncoprotein changes in the flat lesions with atypia and invasive neoplasms of the urinary bladder. Oncol Rep. 8:2001;579-583.
23. Goetze S., Kintscher U., Kaneshiro K., et al. TNFα induces expression of transcription factors c-fos, Egr-1, and Ets-1 in vascular lesions through extracellular signal-regulated kinases 1/2. Atherosclerosis. 159:2001;93-101.
24. Ross J.S., Stagliano N.E., Donovan M.J., Breitbart R.E., Ginsburg G.S. Atherosclerosis and cancer: common molecular pathways of disease development and progression. Ann NY Acad Sci. 947:2001;271-292.