The novel ankyrin-repeat containing kinase ARCK-1 acts as a suppressor of the Spalten signaling pathway during Dictyostelium development

Developmental Biology

Volumn 263, Issue 2, 2003, Pages 308-322

  Aubry, Laurence ^a,b   Lee, Susan ^b   Ravanel, Kissia ^a   Firtel, Richard A ^b  

^a CEA GRENOBLE   (France)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Ankyrin repeats; Cell type differentiation; Dictyostelium; Protein kinase

Indexed keywords

ANKYRIN; PROTEIN SERINE KINASE; THREONINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; DEVELOPMENTAL STAGE; DICTYOSTELIUM; GENE OVEREXPRESSION; GENETIC CODE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TWO HYBRID SYSTEM;

DICTYOSTELIUM; FUNGI; PROTOZOA;

EID: 0242270674     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2003.07.012     Document Type: Article

References (35)

1. Aubry L., Firtel R. Integration of signaling networks that regulate Dictyostelium differentiation. Annu. Rev. Cell Dev. Biol. 15:1999;469-517.
2. Aubry L., Firtel R.A. Spalten, a protein containing Galpha-protein-like and PP2C domains, is essential for cell-type differentiation in Dictyostelium. Genes Dev. 12:1998;1525-1538.
3. Aubry L., Maeda M., Insall R., Devreotes P.N., Firtel R.A. The Dictyostelium mitogen-activated protein kinase ERK2 is regulated by Ras and cAMP-dependent protein kinase (PKA) and mediates PKA function. J. Biol. Chem. 272:1997;3883-3886.
4. Brtva T.R., Drugan J.K., Ghosh S., Terrell R.S., Campbell-Burk S., Bell R.M., Der C.J. Two distinct Raf domains mediate interaction with Ras. J. Biol. Chem. 270:1995;9809-9812.
5. Chubb J.R., Insall R.H. Dictyostelium an ideal organism for genetic dissection of Ras signalling networks . Biochim. Biophys. Acta. 113:2001;262-271.
6. Chubb J.R., Wilkins A., Thomas G.M., Insall R.H. The Dictyostelium RasS protein is required for macropinocytosis, phagocytosis and the control of cell movement. J. Cell Sci. 113:2000;709-719.
7. Chung C.Y., Reddy T.B.K., Zhou K.M., Firtel R.A. A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin-mediated protein degradation. Genes Dev. 12:1998;3564-3578.
8. Clark G.J., Drugan J.K., Rossman K.L., Carpenter J.W., RogersGraham K., Fu H., Der C.J., Campbell S.L. 14-3-3 ζ negatively regulates Raf-1 activity by interactions with the Raf-1 cysteine-rich domain. J. Biol. Chem. 272:1997;20990-20993.
9. Doerks T., Strauss M., Brendel M., Bork P. GRAM, a novel domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins. Trends Biochem. Sci. 25:2000;483-485.
10. Dynes J.L., Firtel R.A. Molecular complementation of a genetic marker in Dictyostelium using a genomic DNA library. Proc. Natl. Acad. Sci. USA. 86:1989;7966-7970.
11. Firtel R.A. Integration of signaling information in controlling cell-fate decisions in Dictyostelium. Genes Dev. 9:1995;1427-1444.
12. Gaskins C., Clark A.M., Aubry L., Segall J.E., Firtel R.A. The Dictyostelium MAP kinase ERK2 regulates multiple, independent developmental pathways. Genes Dev. 10:1996;118-128.
13. Goldberg J.M., Bosgraaf L., van Haastert P.J.M., Smith J.L. Identification of four candidate cGMP targets in Dictyostelium. Proc. Natl. Acad. Sci. USA. 99:2002;6749-6754.
14. Harwood A.J., Plyte S.E., Woodgett J., Strutt H., Kay R.R. Glycogen synthase kinase 3 regulates cell fate in Dictyostelium. Cell. 80:1995;139-148.
15. Hurley J.H., Newton A.C., Parker P.J., Blumberg P.M., Nishizuka Y. Taxonomy and function of C1 protein kinase C homology domains. Protein Sci. 6:1997;477-480.
16. Khosla M., Spiegelman G.B., Insall R., Weeks G. Functional overlap of the Dictyostelium RasG, RasD and RasB proteins. J. Cell Sci. 113:2000;1427-1434.
17. Kim L., Harwood A., Kimmel A.R. Receptor-dependent and tyrosine phosphatase-mediated inhibition of GSK3 regulates cell fate choice. Dev. Cell. 3:2002;523-532.
18. Kim L., Liu J.C., Kimmel A.R. The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification. Cell. 99:1999;399-408.
19. Knetsch M.L.W., van Heusden G.P.H., Ennis H.L., Shaw D.R., Epskamp S.J.P., Snaar-Jagalska B.E. Isolation of a Dictyostelium discoideum 14-3-3 homologue. Biochim. Biophys. Acta. 1357:1997;243-248.
20. Khosla M., Spiegelman G.B., Insall R., Weeks G. Functional overlap of the Dictyostelium RasG, RasD and RasB proteins. J. Cell Sci. 113:2000;1427-1434.
21. Kuspa A., Loomis W.F. Tagging developmental genes in Dictyostelium by restriction enzyme-mediated integration of plasmid DNA. Proc. Natl. Acad. Sci. USA. 89:1992;8803-8807.
22. Lee S., Parent C.A., Insall R., Firtel R.A. A novel Ras interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium. Mol. Biol. Cell. 10:1999;2829-2845.
23. Loomis W.F. Genetic networks that regulate development in Dictyostelium cells. Microbiol. Rev. 60:1996;135.
24. Mann S.K.O., Devreotes P.N., Eliott S., Jermyn K., Kuspa A., Fechheimer M., Furukawa R., Parent C.A., Segall J., Shaulsky G., Vardy P.H., Williams J., Williams K.L., Firtel R.A. Cell biological, molecular genetic, and biochemical methods to examine Dictyostelium. Celis J.E. Cell Biology A Laboratory Handbook . Vol. 1, 2nd Edition:1998;412-451 Academic Press, San Diego.
25. Mann S.K.O., Firtel R.A. cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development. Development. 119:1993;135-146.
26. Mott H.R., Carpenter J.W., Zhong S., Ghosh S., Bell R., Campbell S.L. The solution structure of the Raf-1 cysteine-rich domain a novel Ras and phospholipid binding site . Proc. Natl. Acad. Sci. USA. 93:1996;8312-8317.
27. Schnitzler G.R., Fischer W.H., Firtel R.A. Cloning and characterization of the G-box binding factor, an essential component of the developmental switch between early and late development in Dictyostelium. Genes Dev. 8:1994;502-514.
28. Sedgwick S., Smerdon S. The ankyrin repeat a diversity of interactions on a common structural framework . Trends Biochem. Sci. 24:1999;311-316.
29. Segall J.E., Kuspa A., Shaulsky G., Ecke M., Maeda M., Gaskins C., Firtel R.A. A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium. J. Cell Biol. 128:1995;405-413.
30. Shaulsky G., Escalante R., Loomis W.F. Developmental signal transduction pathways uncovered by genetic suppressors. Proc. Natl. Acad. Sci. USA. 93:1996;15260-15265.
31. Sutherland B.W., Spiegelman G.B., Weeks G. A Ras subfamily GTPase shows cell cycle-dependent nuclear localization. EMBO Rep. 2:2001;1024-1028.
32. Tuxworth R.I., Cheetham J.L., Machesky L.M., Spiegelmann G.B., Weeks G., Insall R.H. Dictyostelium RasG is required for normal motility and cytokinesis, but not growth. J. Cell Biol. 138:1997;605-614.
33. Wilkins A., Khosla M., Fraser D.J., Spiegelman G.B., Fisher P.R., Weeks G., Insall R.H. Dictyostelium RasD is required for normal phototaxis, but not differentiation. Genes Dev. 14:2000;1407-1413.
34. Williams J.G., Harwood A.J., Hopper N.A., Simon M.N., Bouzid S., Veron M. Regulation of Dictyostelium morphogenesis by cAMP-dependent protein kinase. Phil. Trans. R. Soc. Lond. Biol. Sci. 340:1993;305-313.
35. Zhou M., Horita D.A., Waugh D.S., Byrd R.A., Morrison D.K. Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR). J. Mol. Biol. 18:2002;435-446.