Dynamic release of amino acid transmitters induced by valproate in PTZ-kindled epileptic rat hippocampus

Neurochemistry International

Volumn 44, Issue 4, 2004, Pages 263-270

  Li, Zhi Ping ^b   Zhang, Xu Ying ^a   Lu, Xiang ^c   Zhong, Ming Kang ^b   Ji, Yong Hua ^a  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^b FUDAN UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

Amino acid neurotransmitter; Epileptic rat; Hippocampus; Microdialysis; Pentylenetetrazol; Valproate

Indexed keywords

4 AMINOBUTYRIC ACID; AMINO ACID; ASPARTIC ACID; GLUTAMIC ACID; GLYCINE; NEUROTRANSMITTER; PENTETRAZOLE; TAURINE; VALPROIC ACID;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EPILEPSY; EPILEPTOGENESIS; MALE; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE;

EID: 0242268073     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(03)00148-7     Document Type: Article

References (43)

1. Biggs C.S., Pearce B.R., Fowler L.J., Whitton F.S. The effects of sodium valproate on extracellular GABA and other amino acids in the rat ventral hippocampus: an in vivo microdialysis study. Brain Res. 594:1992;138-142.
2. Bradford H.F. Glutamate, GABA and epilesy. Prog. Neurobiol. 47:1995;477-511.
3. Brodie M.J., Dichter M.A. Antiepileptic drugs. N. Engl. J. Med. 334:1996;168-175.
4. Carlson H., Ronne-Engstrom E., Ungerstedt U., Hillered L. Seizure related elevations of exracellular amino acids in human focal epilepsy. Neurosci. Lett. 140:1992;30-32.
5. Chapman A.G. Valproate and myoclonus. Adv. Neurol. 43:1986;661-674.
6. Corda M.G., Giorgi O., Longoni B., Orlandi M., Biggio G. Decrease in the function of the gamma-aminobutyric acid-coupled chloride channel produced by the repeated administration of pentylenetetrazol to rats. J. Neurochem. 55:1990;1216-1221.
7. During M.J., Spencer D.D. Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet. 341:1993;1607-1610A.
8. Engel J.J., Babb T.L., Crandall P.H. Surgical treatment of epilepsy: opportunities for research into basic mechanisms of human brain function. Acta Neurochir. Suppl. (Wien.). 46:1989;3-8.
9. Erdtmann-Vourliotis M., Riechert U., Mayer P., Grecksch G., Hollt V. Pentylenetetrazole (PTZ)-induced c-fos expression in the hippocampus of kindled rats is suppressed by concomitant treatment with naloxone. Brain Res. 792:1998;299-308.
10. Farber N.B., Jiang X.P., Heinkel C., Nemmers B. Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity. Mol. Psychiatr. 7(7):2002;726-733.
11. Fathollahi Y., Motamedi F., Semnanian S., Zardoshti M. Examination of persistent effects of repeated administration of pentylenetetrazol on rat hippocampal CA1: evidence from in vitro study on hippocampal slices. Brain Res. 758:1997;92-98.
12. Fisher R.S. Animal models of the epilepsies. Brain Res. Brain Res. Rev. 14:1989;245-278.
13. Giorgi O., Orlandi M., Lecca D., Corda M.G. MK-801 prevents chemical kindling induced by pentylenetetrazol in rats. Eur. J. Pharmacol. 193:1991;363-365.
14. Hamberger A., Nystrom B., Larsson S., Silfvenius H., Nordborg C. Amino acids in the neuronal microenvironment of focal human epileptic lesions. Epilepsy Res. 9:1991;32-43.
15. Johannessen C.U. Mechanisms of action of valproate: a commentatory. Neurochem. Int. 37:2000;103-110.
16. Kaura S., Bradford H.F., Young A.M.J., Croucher M.J., Hughes P.D. Effect of amygdaloid kindling on the content and release of amino acids from the amygdaloid complex: in vivo and in vitro studies. J. Neurochem. 65:1995;1240-1249.
17. Lindekens H., Smolders I., Khan G.M., Bialer M., Ebinger G., Michotte Y. In vivo study of the effect of valpromide and valnoctamide in the pilocarpine rat model of focal epilepsy. Pharm. Res. 17:2000;1408-1413.
18. Loscher W. Effect of inhibitors of GABA transaminase on the synthesis, binding, uptake, and metabolism of GABA. J. Neurochem. 34:1980;1603-1608.
19. Loscher W. Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acid in the brain. Neurochem. Res. 18:1993;485-502.
20. Loscher W. Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action. Prog. Neurobiol. 58:1999;31-59.
21. Loscher W., Horstermann D. Differential effects of vigabatrin, gamma-acetylenic GABA, aminooxyacetic acid, and valproate on levels of various amino acids in rat brain regions and plasma. Naunyn Schmiedebergs Arch. Pharmacol. 349:1994;270-278.
22. Loscher W., Schmidt D. Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res. 2:1988;145-181.
23. Namba H., Iwasa H., Kubota M., Hagihara Y., Yamaura A. Changes of hippocampal glucose utilization subsequent to amygdaloid-kindled generalized seizres. Epilepsia. 32:1991;27-32.
24. Omrani A., Fathollahi Y., Mohajerani H.R., Semnanian S. Primed-burst potentiation occludes the potentiation phenomenon and enhances the epileptiform activity induced by transient pentylenetetrazol in the CA1 region of rat hippocampal slices. Brain Res. 887:2000;176-183.
25. Parada A., Soares-da-Sillva P. The novel anticonvulsant BIA 2-093 inhibits transmitter release during opening of voltage-gated sodium channels: a comparison with carbamazepine and oxcarbazepine. Neurochem. Int. 40:2002;435-440.
26. Pena F., Tapia R. Seizures and neurodegeneration induced by 4-aminopyridine in rat hippocampus in vivo: role of glutamate- and GABA-mediated neurotransmission and of ion channels. Neuroscience. 101:2000;547-561.
27. Petroff O.A.C., Rothman D.L., Behar K.L., Hyder F., Mattson R.H. Effects of valproate and other antiepileptic drugs on brain glutamate, glutamine, and GABA in patients with refractory complex partial seizures. Seizures. 8:1999;120-127.
28. Ramanjaneyulu R., Ticku M.J. Interaction of pentamethylenetetrazole and tetrazole analogues with the picrotoxin in site of the benzodiazepine-GABA receptor-ionophore complex. Eur. J. Pharmacol. 98:1984;337-345.
29. Rogawski M.A., Porter R.J. Antiepileptic drugs: pharmacological mechanisms and clinical efficacy with consideration of promising developmental stage compounds. Pharmacol. Rev. 42:1990;223-286.
30. Rowley H.L., Marsdern C.A., Martin K.F. Differential effects of phenytoin and sodium valproate on seizure-induced changes in γ-aminobutyric acid and glutamate release in vivo. Eur. J. Pharmacol. 294:1995a;541-546.
31. Rowley H.L., Martin K.F., Marsdern C.A. Decreased GABA release following tonic-clonic seizures is associated with an increase in extracellular glutamate in rat hippocampus in vivo. Neuroscience. 68:1995b;415-422.
32. Sayin U., Timmerman W., Westerink B.H. The significance of extracellular GABA in the substantia nigra of the rat during seizures and anticonvulsant treatments. Brain Res. 669:1995;67-72.
33. Schroder H., Becker A. The role of glutamate receptors in pentylenetetrazole kindling of rats - a neurochemical study. Neuropharmacology. 35:1996;A28.
34. Schroder H., Becker A., Hollt V. Sensitivity and density of glutamate receptor subtypes in the hippocampal formation are altered in pentylenetetrazol-kindled rats. Exp. Brain Res. 120:1998;527-530.
35. Schroder H., Becker A., Loβner B. Glutamate binding to brain membrane is increased in pentylenetetrazole-kindled rats. J. Neurochem. 60:1993;1007-1011.
36. Schroder H., Schlichthaar R., Krug M. Changes of glutamatergic synaptic mechanisms after PTZ kindling and LTP. Neuroscience. 60:1994;337-342.
37. 3H -D-aspartate release from hippocampal tissue during the development of pentylenetetrazol kindling in rats Pharmacol. Biochem. Behav. 62:1999;349-352.
38. Sugaya E., Onozuka M. Intracellular calcium-its release from granules during bursting activity in snail neurons. Science. 202:1978;1195-1197.
39. Taylor C.P. How do seizures begin? Clues from hippocampal slices. Trends Neurosci. 11:1988;375-378.
40. Turski L., Ikonomidou C., Turski W.A., Bortolotto Z.A., Cavalheiro E.A. Review: cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy. Synapse. 3:1989;154-171.
41. Van Gelder N.M. Contributions of basic neurochemistry towards a novel concept of epilepsy. Neurochem. Res. 12:1987;111-119.
42. Wheler G.H., Osborne R.H., Bradford H.F., Davison A.N. Uptake studies of taurine in vivo and its effects on the course of experimental focal epilepsy in rats. Brain Res. 136:1977;535-542.
43. Zhang X.Y., Zhang J.W., Chen B., Bai Z.T., Shen J., Ji Y.H. Dynamic determination and possible mechanism of amino acid transmitter release from rat spinal dorsal horn induced by Asia scorpion venom and neurotoxin, BmK I. Brain Res. Bull. 58:2002;27-31.