Hypothermia attenuates delayed cortical cell death and ROS generation following CO inhalation

Toxicology Letters

Volumn 145, Issue 2, 2003, Pages 101-106

  Uemura, Koichi ^a   Hoshino, Sumihisa ^a   Uchida, Koji ^b   Tsuruta, Ryosuke ^c   Maekawa, Tsuyoshi ^c   Yoshida, Ken Ichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Carbon monoxide; HNE; Hyperthermia; Hypothermia; Rat brain

Indexed keywords

CARBON MONOXIDE; NITROUS OXIDE; OXYGEN; REACTIVE OXYGEN METABOLITE;

ACCIDENT; AIR CONDITIONING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATTENUATION; BASAL GANGLION; BODY TEMPERATURE; BRAIN CELL; BRAIN CORTEX; BRAIN DEATH; BRAIN INJURY; CELL DEATH; CONTROLLED STUDY; CONVALESCENCE; DELAYED NEUROTOXICITY; DEVICE; EOSINOPHIL; HIPPOCAMPUS; HISTOLOGY; HYPERTHERMIA; HYPOTHERMIA; HYPOXIA; IMMUNOREACTIVITY; INHALATION; MALE; NERVE CELL; NONHUMAN; OXYGEN TENSION; PRIORITY JOURNAL; RAT; REOXYGENATION; SKULL; TEMPERATURE;

EID: 0142258684     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(03)00202-9     Document Type: Article

References (17)

1. Brown S.D., Piantadosi C.A. In vivo binding of carbon monoxide to cytochrome c oxidase in rat brain. J. Appl. Physiol. 68:1990;604-610.
2. Caughey W.S. Carbon monoxide bonding in hemeproteins. Ann. New York Acad. Sci. 174:1970;148-153.
3. Esterbauer H., Schaur R.J., Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 11:1991;81-128.
4. Ginsberg M.D. Delayed neurological deterioration following hypoxia. Adv. Neurol. 26:1979;21-47.
5. Kruman I., Bruce-Keller A.J., Bredesen D., Waeg G., Mattson M.P. Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis. J. Neurosci. 17:1997;5089-5100.
6. Kudo R., Adachi J., Uemura K., Maekawa T., Ueno Y., Yoshida K. Lipid peroxidation in rat brain after CO inhalation is temperature-dependent. Free Radic. Biol. Med. 31:2001;1417-1423.
7. Maekawa T., Sadamitsu D., Tsuruta R., Inoue T., Tateishi A., Murakami F. Mild hypothermia therapy for severe acute brain insults in clinical practice. Hayashi N. Brain Hypothermia: Pathology, Pharmacology, and Treatment of Severe Brain Injury. 2000;175-185 Springer, Tokyo.
8. McCracken E., Valeriani V., Simpson C., Jover T., McCulloch J., Dewar D. The lipid peroxidation by-product 4-hydroxynonenal is toxic to axons and oligodendrocytes. J. Cereb. Blood Flow Metab. 20:2000;1529-1536.
9. Piantadosi C.A., Zhang J., Levin E.D., Folz R.J., Schmechel D.E. Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat. Exp. Neurol. 147:1997;103-114.
10. Piantadosi C.A., Zhang J., Demchenko I.T. Production of hydroxyl radical in the hippocampus after CO hypoxia or hypoxic hypoxia in the rat. Free Radic. Biol. Med. 22:1997;725-732.
11. Sawada Y., Sakamoto T., Nishide K., Sadamitsu D., Fusamoto H., Yoshioka T., Sugimoto T. Correlation of pathological findings with computed tomographic findings after acute carbon monoxide poisoning. New Engl. J. Med. 308:1983;1296.
12. Thom S.R., Fisher D., Xu Y.A., Notarfrancesco K., Ischiropoulos H. Adaptive responses and apoptosis in endothelial cells exposed to carbon monoxide. Proc. Natl. Acad. Sci. USA. 97:2000;1305-1310.
13. Uchida K., Shiraishi M., Naito Y., Torii Y., Nakamura Y., Osawa T. Activation of stress signaling pathways by the end product of lipid peroxidation. 4-Hydroxy-2-nonenal is a potential inducer of intracellular peroxide production. J. Biol. Chem. 274:1999;2234-2242.
14. Uemura K., Harada K., Sadamitsu D., Tsuruta R., Takahashi M., Aki T., Yasuhara M., Maekawa T., Yoshida K. Apoptotic and necrotic brain lesions in a fatal case of carbon monoxide poisoning. Forensic Sci. Int. 116:2001;213-219.
15. Urabe T., Hattori N., Yoshikawa M., Yoshino H., Uchida K., Mizuno Y. Colocalization of Bcl-2 and 4-hydroxynonenal modified proteins in microglial cells and neurons of rat brain following transient focal ischemia. Neurosci. Lett. 247:1998;159-162.
16. Young L.J., Caughey W.S. Pathobiochemistry of CO poisoning. FEBS Lett. 272:1990;1-6.
17. Zhang J., Piantadosi C.A. Mitochondrial oxidative stress after carbon monoxide hypoxia in the rat brain. J. Clin. Invest. 90:1992;1193-1199.