Coincubation of tissue slices, a new way to study metabolic cooperation between organs: Hepatorenal cooperation in the biotransformation of CGP 47 969 A

Journal of Pharmacological and Toxicological Methods

Volumn 48, Issue 2, 2002, Pages 119-126

  Kretz, O ^a   Guenat, C ^a   Beilstein, P ^b   Gross, G ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b SYNGENTA CROP PROTECTION AG   (Switzerland)

Author keywords

Glutathione conjugate; Kidney; Liver; Metabolic cooperation; Rat; Slices

Indexed keywords

1 [4 [N CHLOROACETYL N (2 ISOPROPOXYETHYL)AMINO]BENZOYL] 4 [2 (4 CHLOROPHENYL)ETHYL]PIPERAZINE; ACETYLCYSTEINE;

ANIMAL TISSUE; ARTICLE; DEGRADATION; DRUG CONJUGATION; DRUG METABOLISM; DRUG TRANSFORMATION; IN VITRO STUDY; INCUBATION TIME; KIDNEY SLICE; LIVER SLICE; MALE; NONHUMAN; RAT;

EID: 0142248970     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(03)00039-X     Document Type: Article

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