Forebrain and brain stem neural circuits contribute to altered sympathetic responses to heating in senescent rats

Journal of Applied Physiology

Volumn 95, Issue 5, 2003, Pages 1986-1993

  Kenney, Michael J ^a   Fels, Richard J ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

Decerebration; Fischer 344 rats; Sympathetic nerve activity; Sympathetic nerve discharge

Indexed keywords

ADOLESCENT; AGED; AGING; ANIMAL EXPERIMENT; ARTICLE; BRAIN INJURY; BRAIN STEM; CERVICAL SPINAL CORD INJURY; CONTROLLED STUDY; DECEREBRATION; FOREBRAIN; HEATING; KIDNEY NERVE; MEAN ARTERIAL PRESSURE; MESENCEPHALON; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; SENESCENCE; SPLANCHNIC NERVE; SYMPATHETIC NERVE; SYMPATHETIC NERVE ACTIVITY; SYMPATHETIC NERVE DISCHARGE; SYMPATHETIC REFLEX; SYMPATHETIC TONE; VISCERA;

EID: 0142211398     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00438.2003     Document Type: Article

References (41)

1. American Physiological Society. Guiding principles for research involving animals and human beings. Am J Physiol Regul Integr Comp Physiol 283: R281-R283, 2002.
2. Armstrong CG and Kenney WL. Effects of age and acclimation on responses to passive heat exposure. J Appl Physiol 75: 2162-2167, 1993.
3. Barman SM. Brainstem control of cardiovascular function. In: Brainstem Mechanisms of Behavior, edited by Klemm WR and Vertes RP. New York: John Wiley and Sons, 1990, p. 353-381.
4. Blessing WW. Depressor neurons in rabbit caudal medulla act via GABA receptors in rostral medulla. Am J Physiol Heart Circ Physiol 254: H686-H692, 1988.
5. Cabanac M. Heat stress and behavior. In: Handbook of Physiology. Adaptation to the Environment. Bethesda, MD: Am. Physiol. Soc., 1996, sect. 4, vol. I, chapt. 13, p. 261-278.
6. Chai CY and Lin MT. Effects of thermal stimulation of medulla oblongata and spinal cord on decerebrate rabbits. J Physiol 234: 409-419, 1973.
7. Cox B, Lee TF, and Parkes J. Decreased ability to cope with heat and cold linked to a dysfunction in a central dopaminergic pathway in elderly rats. Life Sci 28: 2039-2044, 1981.
8. Crandall CG, Etzel RA, and Farr DB. Cardiopulmonary baroreceptor control of muscle sympathetic nerve activity in heat-stressed humans. Am J Physiol Heart Circ Physiol 277: H2348-H2352, 1999.
9. Dampney RAL. Functional organization of central pathways regulating the cardiovascular system. Physiol Rev 74: 323-364, 1994.
10. Delius W, Hagbarth KE, Hongell A, and Wallin BG. Manoeuvers affecting sympathetic outflow in human skin nerves. Acta Physiol Scand 84: 177-186, 1972.
11. Gabbott GR and Jones DR. The effect of brain transection on the response to forced submergence in ducks. J Auton Nerv Syst 36: 65-74, 1991.
12. Gisolfi CV, Matthes RD, Kregel KC, and Oppliger R. Splanchnic sympathetic nerve activity and circulating catecholamines in the hyperthermic rat. J Appl Physiol 70: 1821-1826, 1991.
13. Iriki M and Kozawa E. Patterns of differentiation in various sympathetic efferents induced by hypoxic and by central thermal stimulation in decerebrated rabbits. Pflügers Arch 362: 101-108, 1976.
14. Ito S and Sved AF. Blockade of angiotensin receptors in rat rostral ventrolateral medulla removes excitatory vasomotor tone. Am J Physiol Regul Integr Comp Physiol 270: R1317-R1323, 1996.
15. Johnson CD and Gilbey MP. Sympathetic activity recorded from the rat caudal ventral artery in vivo. J Physiol 476: 437-442, 1994.
16. Kenney MJ, Barney CC, Hirai T, and Gisolfi CV. Sympathetic nerve responses to hyperthermia in the anesthetized rat. J Appl Physiol 78: 881-889, 1995.
17. Kenney MJ, Claassen DE, Bishop MR, and Fels RJ. Regulation of the sympathetic nerve discharge bursting pattern during heat stress. Am J Physiol Regul Integr Comp Physiol 275: R1992-R2001, 1998.
18. Kenney MJ and Fels RJ. Sympathetic nerve regulation to heating is altered in senescent rats. Am J Physiol Regul Integr Comp Physiol 283: R513-R520, 2002.
19. Kenney MJ, Musch TI, and Weiss ML. Renal sympathetic nerve regulation to heating is altered in rats with heart failure. Am J Physiol Heart Circ Physiol 280: H2868-H2875, 2001.
20. Kenney MJ, Pickar JG, Weiss ML, Saindon CS, and Fels RJ. Effects of midbrain and spinal cord transections on sympathetic nerve responses to heating. Am J Physiol Regul Integr Comp Physiol 278: R1329-R1338, 2000.
21. Kregel KC and Gisolfi CV. Circulatory responses to heat after celiac ganglionectomy or adrenal demedullation. J Appl Physiol 66:1359-1363, 1989.
22. Kregel KC, Stauss H, and Unger T. Modulation of autonomic nervous system adjustments to heat stress by central ANG II receptor antagonism. Am J Physiol Regul Integr Comp Physiol 266: R1985-R1991, 1994.
23. Kregel KC, Wall PT, and Gisolfi CV. Peripheral vascular responses to hyperthermia in the rat. J Appl Physiol 64: 2582-2588, 1988.
24. Li YW, Gieroba ZJ, McAllen RM, and Blessing WW. Neurons in rabbit caudal ventrolateral medulla inhibit bulbospinal barosensitive neurons in rostral medulla. Am J Physiol Regul Integr Comp Physiol 261: R44-R51, 1991.
25. Lipski J, Kanjhan R, Kruszewska B, and Rong W. Properties of presympathetic neurones in the rostral ventrolateral medulla in the rat: an intracellular study "in vivo." J Physiol 490: 729-744, 1996.
26. Loewy AD. Central autonomic pathways. In: Central Regulation of Autonomic Functions, edited by Loewy AD and Spyer KM. New York: Oxford University Press, 1990, p. 88-103.
27. Meagher MW, Grau JW, and King RA. Role of supraspinal systems in environmentally induced antinociception: effect of spinalization and decerebration on brief shock-induced and long shock-induced antinociception. Behav Neurosci 104: 328-338, 1990.
28. Minson CT, Wladkowski SL, Cardell AF, Pawelczyk JA, and Kenney WL. Age alters the cardiovascular response to direct passive heating. J Appl Physiol 84: 1323-1332, 1998.
29. A inhibition of the RVLM after hindlimb unloading in rats. Am J Physiol Regul Integr Comp Physiol 283: R604-R614, 2002.
30. Morrison SF. Differential control of sympathetic outflow. Am J Physiol Regul Integr Comp Physiol 281: R683-R698, 2001.
31. Niimi Y, Matsukawa T, Sugiyama Y, Shamsuzzaman ASM, Ito H, Sobue G, and Mano T. Effect of heat stress on muscle sympathetic nerve activity in humans. J Auton Nerv Syst 63: 61-67, 1997.
32. Nosaka S, Murata K, Kobayashi M, Cheng ZB, and Maruyama J. Inhibition of baroreflex vagal bradycardia by activation of the rostral ventrolateral medulla in rats. Am J Physiol Heart Circ Physiol 279: H1239-H1247, 2000.
33. Ono H, Nakamura T, Ito H, Oka J, and Fukuda H. Rigidity in rats due to radio frequency decerebration and effects of chlorpromazine and mephenesin. Gen Pharmacol 18: 57-59, 1987.
34. Osaka T, Kobayashi A, Lee TH, Namba Y, Inoue S, and Kimura S. Lack of integrative control of heat production and heat loss after capsaicin administration. Pflügers Arch 440: 440-445, 2000.
35. Osborn JW, Livingstone RH, and Schramm LP. Elevated renal nerve activity after spinal transection: effects on renal function. Am J Physiol Regul Integr Comp Physiol 253: R619-R625, 1987.
36. Ross CA, Ruggiero DA, Park DH, Joh TH, Sved AF, Fernandez-Pardal J, Saavedra JM, and Reis DJ. Tonic vasomotor control by the rostral ventrolateral medulla: effect of electrical or chemical stimulation of the area containing cl adrenaline neurons on arterial pressure, heart rate, and plasma catecholamines and vasopressin. J Neurosci 4: 474-494, 1984.
37. Rowell LB. Cardiovascular adjustments to thermal stress. In: Handbook of Physiology. The Cardiovascular System. Peripheral Circulation and Organ Blood Flow. Bethesda, MD: Am. Physiol. Soc., 1983, sect. 2, vol. III, chapt. 27, p. 967-1023.
38. Stauss HM, Morgan DA, Anderson KE, Massett MP, and Kregel KC. Modulation of baroreflex sensitivity and spectral power of blood pressure by heat stress and aging. Am J Physiol Heart Circ Physiol 272: H776-H784, 1997.
39. Sun MK. Central neural organization and control of sympathetic nervous system in mammals. Prog Neurobiol 47: 157-233, 1995.
40. Sun MK and Reis D. Decerebration does not alter hypoxic sympathoexcitatory responses in rats. J Auton Nerv Syst 53: 77-81, 1995.
41. Taylor RF and Schramm LP. Differential effects of spinal transection on sympathetic nerve activities in rats. Am J Physiol Regul Integr Comp Physiol 253: R611-R618, 1987.