Increased GABAA inhibition of the RVLM after hindlimb unloading in rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 283, Issue 3 52-3, 2002, Pages

  Moffitt, Julia A ^a   Heesch, Cheryl M ^a   Hasser, Eileen M ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

Bedrest; Cardiovascular deconditioning; Caudal ventrolateral medulla; Microgravity; Orthostatic intolerance; Spaceflight; Sympathetic nervous system

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; BICUCULLINE METHIODIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; GABAERGIC SYSTEM; HEART RATE; HINDLIMB; HYPOTENSION; KIDNEY NERVE; MALE; MEAN ARTERIAL PRESSURE; MEDULLA OBLONGATA; NERVE CONDUCTION; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RAT; SYMPATHETIC NERVE;

EID: 0036724034     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00341.2001     Document Type: Article

References (53)

1. B receptors in tonic inhibitory control of blood pressure at the rostral ventrolateral medulla of the rat
2. B receptor antagonists
3. Cardiovascular adjustments to gravitational stress
4. Orthostatic intolerance after spaceflight
5. Cardiovascular deconditioning during space flight and the use of saline as a countermeasure to orthostatic intolerance
6. The metabolic and hemodynamic effects of prolonged bed rest in normal subjects
7. Sympathoinhibition evoked from caudal midline medulla is mediated by GABA receptors in rostral VLM
8. Head-down bed rest impairs vagal baroreflex responses and provokes orthostatic hypotension
9. Cardiovascular responses to exercise in middle-aged men after 10 days of bedrest
10. The spinal organisation of the baroreceptor reflex
11. Differentiation of two cardiovascular regions within caudal ventrolateral medulla
12. The subretrofacial vasomotor nucleus: Anatomical, chemical and pharmacological properties and role in cardiovascular regulation
13. Spaceflight alters autonomic regulation of arterial pressure in humans
14. Results of a 4-week head-down tilt with and without LBNP countermeasure. I. Volume regulating hormones
15. Area postrema and aortic or vagal afferents converge to excite cells in the nucleus tractus solitarius
16. Inhibitory and excitatory inputs from caudal ventrolateral medulla (CVLM) to rostral ventrolateral medulla (RVLM) in rats
17. Mechanisms for decreased exercise capacity after bedrest in normal middle-aged men
18. Blockade of angiotensin receptors in rat rostral ventrolateral medulla removes excitatory vasomotor tone
19. Tonic glutamate-mediated control of rostral ventrolateral medulla and sympathetic vasomotor tone
20. Atrophy and growth failure of rat hindlimb muscles in tail-cast suspension
21. Role of rostral ventrolateral medulla centrally mediated pressor responses
22. Neurosteroid modulation of arterial baroreflex-sensitive neurons in rat rostral ventrolateral medulla
23. Critical discussion of research issues in mechanisms of cardiovascular adaptation to actual and simulated μG
24. Maximal exercise performance after adaptation to microgravity
25. Neurons in rabbit caudal ventrolateral medulla inhibit bulbospinal barosensitive neurons in rostral medulla
26. Effect of substance P on C1 and other bulbospinal cells of the RVLM in neonatal rats
27. Properties of presympathetic neurones in the rostral ventrolateral medulla in the rat: An intracellular study 'in vivo'
28. Central hypervolemia in the conscious rat: A model of cardiovascular deconditioning
29. GABA-mediated inhibition of sympathoexcitatory neurons by midline medullary stimulation
30. Evidence for GABA mediation of sympathetic inhibition evoked from midline medullary depressor sites
31. Effect of hindlimb unweighting on tissue blood flow in the rat
32. Attenuated baroreflex control of sympathetic nerve activity after cardiovascular deconditioning in rats
33. Altered central nervous system processing of baroreceptor input following hindlimb unloading in rats
34. Responses of sympathetic preganglionic neurons to rostral ventrolateral medullary stimulation
35. Rat cardiovascular responses to whole body suspension: Head-down and non-head-down tilt
36. Sympathoexcitatory CVLM neurons mediate responses to caudal pressor area stimulation
37. Effect of hindlimb suspension on cardiovascular responses to sympathomimetics and lower body negative pressure
38. 2 max and regional blood flow responses to exercise
39. Tonic vasomotor control by the rostral ventrolateral medulla: Effect of electrical or chemical stimulation of the area containing c1 adrenaline neurons on arterial pressure, heart rate, and plasma catecholamines and vasopressin
40. Renal sympathetic baroreflex effects of angiotensin II infusions into the rostral ventrolateral medulla of the rabbit
41. Response to exercise after bed rest and after training
42. Early central venous pressure changes in the rat during two different levels of head-down suspension
43. GABAergic responses in ventrolateral medulla in spontaneously hypertensive rats
44. Effects of bed rest on cardiovascular function and work performance
45. Atrophy of the soleus muscle by hindlimb unweighting
46. Aspects of cardiovascular reflex control in man. An experimental study
47. The inhibitory effect of the ventrolateral periaqueductal grey matter on neurones in the rostral ventrolateral medulla involves a relay in the medullary raphe nuclei
48. GABAergic mechanisms in the ventrolateral medulla alter vasopressor responses from the anterior hypothalamus
49. Medullary γ-aminobutyric acid (GABA) receptors and the regulation of blood pressure in the rat
50. Cardiovascular control by cholingergic mechanisms in the rostral ventrolateral medulla
51. Area postrema excites and inhibits sympathetic-related neurons in the rostral ventrolateral medulla in rabbit