Attrition and Translation

Science

Volumn 302, Issue 5645, 2003, Pages 603-605

  Duyk, Geoffrey ^a  

^a EXELIXIS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COSTS; DIAGNOSIS; GENETIC ENGINEERING;

ATTRITION;

HEALTH CARE;

GENETICS; RESEARCH AND DEVELOPMENT;

BIOMEDICINE; BIOTECHNOLOGY; CLINICAL RESEARCH; COST EFFECTIVENESS ANALYSIS; DNA SEQUENCE; FINANCIAL MANAGEMENT; FOOD AND DRUG ADMINISTRATION; GENETICS; GENOME; HEALTH CARE COST; INFORMATION SYSTEM; MEDICAL RESEARCH; MOLECULAR GENETICS; MOLECULAR MECHANICS; PHYSIOLOGY; PRACTICE GUIDELINE; PRIORITY JOURNAL; REVIEW; TRANSLATION REGULATION; TRANSLATIONAL RESEARCH; UNIVERSITY HOSPITAL; XENOBIOTIC METABOLISM;

ACCESS TO INFORMATION; BIOLOGICAL SCIENCES; BIOMEDICAL RESEARCH; BIOTECHNOLOGY; CHEMISTRY, PHARMACEUTICAL; CLINICAL TRIALS; COSTS AND COST ANALYSIS; DRUG INDUSTRY; GUIDELINES; HUMANS; MOLECULAR BIOLOGY; PHARMACEUTICAL PREPARATIONS; PHARMACOLOGY; PHYSIOLOGY; PRIVATE SECTOR; PUBLIC SECTOR; RESEARCH SUPPORT;

EID: 0142209376     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1090521     Document Type: Review

References (18)

1. F. S. Collins, E. D. Green, A. E. Guttmacher, M. S. Guyer, Nature 422, 835 (2003).
2. E. Zerhouni, Science 302, 63 (2003).
3. Bill and Melinda Gates Foundation, Global Health Program (www.gatesfoundation.org/GlobalHealth).
4. Cystic Fibrosis Foundation (www.cff.org).
5. K. I. Kaitin, Ed., Tufts Center for the Study of Drug Development Impact Report 5 (May/June 2003) (http://csdd.tufts.edu).
6. C.-P. Milne, L. Lasagna, Eds., special issue on The Cost and Value of New Medicines in an Era of Change, Pharmacoeconomics 20 (suppl. 3) (2002).
7. J. A. DiMasi, Am. J. Ther. 3, 647 (1996).
8. J.A. DiMasi, N. R. Bryant, L. Lasagna, Clin. Pharmacol. Ther. 50, 471 (1991).
9. J. A. DiMasi, Clin. Pharmacol. Ther. 69, 286 (2001).
10. The Fruits of Genomics: Drug Pipelines Face Indigestion Until the New Biology Ripens (Lehman Brothers, New York, 2001).
11. F. S. Collins, M. Morgan, A. Patrinos, Science 300, 286 (2003).
12. M. C. Falk, N. J. Emenaker, Eds., The Status and Future of Integrative and Organ Systems Sciences in the U.S. (Life Sciences Research Office, Bethesda, MD, 2003).
13. "Sharing Data from Large-Scale Biological Research Projects," meeting sponsored by the Wellcome Trust, Fort Lauderdale, FL, January 2003 (www.wellcome.ac.uk/en/1/awtpubrepdat.html).
14. M. B. McClellan, speech before the Commonwealth Club, San Francisco, 9 June 2003 (www.fda.gov/oc/speeches/2003/commonwealth0609.html).
15. D. Malakoff, Science 300, 1635 (2003).
16. R. S. Eisenberg, Science 299, 1018 (2003).
17. M. A. Heller, R. S. Eisenberg, Science 280, 698 (1998).
18. The opinions stated in this article are those of the author and not necessarily the opinions of Exelixis Inc. or its partners.