The Human Genome Project: Lessons from large-scale biology

Science

Volumn 300, Issue 5617, 2003, Pages 286-290

  Collins, Francis S ^a   Morgan, Michael ^b   Patrinos, Aristides ^c  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c U S DEPARTMENT OF ENERGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL ENGINEERING; MEDICAL APPLICATIONS;

HUMAN GENOME PROJECT;

GENETIC ENGINEERING;

BIOLOGY; GENOME;

GENE MAPPING; GENE SEQUENCE; HEALTH CARE ORGANIZATION; HUMAN GENOME; INTERNATIONAL COOPERATION; MEDICAL GENETICS; MEDICAL RESEARCH; PRIORITY JOURNAL; QUALITY CONTROL; REVIEW;

ACCESS TO INFORMATION; COMPUTATIONAL BIOLOGY; DATABASES, NUCLEIC ACID; GENOME, HUMAN; GENOMICS; GOVERNMENT AGENCIES; HISTORY, 20TH CENTURY; HUMAN GENOME PROJECT; HUMANS; INTERNATIONAL COOPERATION; NATIONAL INSTITUTES OF HEALTH (U.S.); PRIVATE SECTOR; PUBLIC POLICY; PUBLIC SECTOR; PUBLISHING; QUALITY CONTROL; SEQUENCE ANALYSIS, DNA; UNITED STATES;

EID: 0037432755     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1084564     Document Type: Review

References (16)

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8. F. S. Collins et al., Science 282, 682 (1998).
9. NHGRI Standard for Quality of Human Genomic Sequence [revised 10 February 2002]. Available at www.genome.gov/page.cfm?pageID=10000923.
10. "Sharing Data from Large-scale Biological Research Projects," meeting sponsored by The Wellcome Trust, Fort Lauderdale, FL, January 2003. Available at www.wellcome.ac.uk/en/1/awtpubrepdat.html.
11. The ENCODE Project: ENCyclopedia Of DNA Elements [updated February 2003]. Available at www. genome.gov/Pages/Research/ENCODE/.
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13. Genomes to Life [updated 26 February 2003]. Available at http://doegenomestolife.org.
14. NHGRI, The Haplotype Map. Available at www. genome.gov/Pages/Research/HapMap.
15. F. S. Collins et al., Nature, in press.
16. We express our profound gratitude to leaders of all of the sequencing centers involved in the International Human Genome Sequencing Consortium, along with all other participants in the HGP, 1990 to 2003.