Polymerase chain reaction-single-strand conformation polymorphism analysis for the VHL gene in chemically induced kidney tumors of rats using intron-derived primers

Molecular Carcinogenesis

Volumn 19, Issue 4, 1997, Pages 230-235

  Shiao, Yih Horng ^a   Diwan, Bhalchandra A ^b   Perantoni, Alan O ^a   Calvert, Richard J ^c   Zbar, Berton ^a   Lerman, Michael I ^b   Rice, Jerry M ^d  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^d INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

Author keywords

Introns; Rat kidney tumors; von Hippel Lindau gene

Indexed keywords

ETHYLNITROSOUREA; MUTANT PROTEIN; N NITROSOETHYL(2 HYDROXYETHYL)AMINE; N NITROSOMETHYL(METHOXYMETHYL)AMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; EPITHELIUM TUMOR; GENE AMPLIFICATION; GENE ISOLATION; GENE MUTATION; HUMAN; HUMAN CELL; INTRON; KIDNEY CARCINOMA; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; VON HIPPEL LINDAU DISEASE;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; DNA, NEOPLASM; EPITHELIUM; EXONS; GENETIC SCREENING; HIPPEL-LINDAU DISEASE; INTRONS; KIDNEY NEOPLASMS; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RATS; RATS, INBRED F344; WILMS TUMOR;

ANIMALIA;

EID: 0030842661     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199708)19:4<230::AID-MC3>3.0.CO;2-G     Document Type: Article

References (31)

1. Neumann HPH, Lips CJM, Hsia YE, Zbar B. Von Hippel-Lindau syndrome. Brain Pathol 5:181-193, 1995.
2. Crossey PA, Richards FM, Foster K, et al. Identification of in- tragenic mutations in the Von Hippel-Lindau disease tumour suppressor gene and correlation with disease phenotype. Hum Mol Genet 3:1303-1308, 1994.
3. Chen F, Kishida T, Yao M, et al. Germline mutations in the von Hippel-Lindau disease tumor suppressor gene:Correlations with phenotype. Hum Mutat 5:66-75, 1995.
4. Shuin T, Kondo K, Torigoe S, et al. Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinoma. Cancer Res 54:2852-2855, 1994.
5. Bailly M, Bain C, Favrot M-C, Ozturk M. Somatic mutations of von Hippel-Lindau (VHL) tumor-suppressor gene in European kidney cancers. Int J Cancer 63:660-664, 1995.
6. Whaley JM, Naglich J, Gelbert L, et al. Germ-line mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma. Am J Hum Genet 55:1092-1102, 1994.
7. Gnarra JR, Tory K, Weng Y, et al. Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat Genet 7:85-90, 1994.
8. Gnarra JR, Duan DR, Weng Y, et al. Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma. Biochim Biophys Acta 1242:201-210, 1996.
9. Hard GC. Renal carcinogenesis, rat. In:Jones TC, Mohr U, Hunt RD (eds), Monographs on Pathology of Laboratory Animals:Urinary System. Springer-Verlag, Berlin, 1986, pp. 45-49.
10. Bannasch P, Zerban H. Animal models and renal carcinogenesis. In:Eble JN (ed), Tumors and Tumor-Like Conditions of the Kidneys and Ureters. Churchill Livingstone, New York, 1990, pp. 1-34.
11. Kikuchi Y, Kobayashi E, Nishizawa M, Hamazaki S, Okada S, Hino O. Cloning of the rat homologue of the von Hippel-Lindau tumor suppressor gene and its non-somatic mutation in rat renal cell carcinomas. Jpn J Cancer Res 86:905-909, 1995.
12. ++ transporting ATPase isoform 2 (Atp2b2) gene to rat chromosome bands 4q41.3-42.1. Cytogenet Cell Genet 71:253-256, 1995.
13. Hiasa Y, Enoki N, Kitahori Y, Konishi N, Shimoyama T. DL-serine:Promoting activity on renal tumorigenesis by N-ethyl-Nhydroxyethylnitrosamine in rats. J Natl Cancer Inst 73:297-299, 1984.
14. Diwan BA, Rice JM. Effect of stage of development on frequency and pathogenesis of kidney tumors induced in Noble (Nb) rats exposed prenatally or neonatally to N-nitrosoethylurea. Carcinogenesis 16:2023-2028, 1995.
15. Sukumar S, Perantoni A, Reed C, Rice JM, Wenk ML. Activated K-ras and N-ras oncogenes in primary renal mesenchymal tumors induced in F344 rats by methyl(methoxymethyl)nitrosamine. Mol Cell Biol 6:2716-2720, 1986.
16. Hongyo T, Buzard GS, Palli D, et al. Mutations of the K-ras and p53 genes in gastric adenocarcinomas from a high-incidence region around Florence, Italy. Cancer Res 55:2665-2672, 1995.
17. Wright DK, Manos MM. Sample preparation from paraffin embedded tissue. In:Innis MA, Gelfand DH, Sninsky JJ, White TJ (eds), PCR Protocols:A Guide to Methods and Applications. Academic Press, San Diego, 1990, pp. 153-158.
18. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215, 1988.
19. Pulciani S, Santos E, Lauver AV, Long LK, Aaronson SA, Barbacid M. Oncogenes in solid human tumours. Nature 300:539-542, 1982.
20. Labarca C, Paigen K. A simple, rapid, and sensitive DNA assay procedure. Anal Biochem 102:344-352, 1980.
21. Hongyo T, Buzard GS, Calvert RJ, Weghorst CM. "Cold SSCP":A simple, rapid and non-radioactive method for optimized singlestrand conformation polymorphism analyses. Nucleic Acids Res 21:3637-3642, 1993.
22. Hard GC, Grasso P. Nephroblastoma in the rat:Histology of a spontaneous tumor, identity with respect to renal mesenchymal neoplasms, and a review of previously recorded cases. J Natl Cancer Inst 57:323-329, 1976.
23. Hard GC, Butler WH. Cellular analysis of renal neoplasia:Light microscope study of the development of interstitial lesions induced in the rat kidney by a single carcinogenic dose of dimeth ylnitrosamine. Cancer Res 30:2806-2815, 1970.
24. Hard GC, Butler WH. Ultrastructural analysis of renal mesenchymal tumor induced in the rat by dimethylnitrosamine. Cancer Res 31:348-365, 1971.
25. Hard GC. Differential renal tumor response to N-ethylnitrosourea and dimethylnitrosamine in the Nb rat:Basis for a new rodent model of nephroblastoma. Carcinogenesis 6:1551-1558, 1985.
26. Oberling C, Riviere M, Haguenau F. Ultrastructure of the clear cells in renal carcinomas and its importance for the demonstration of their renal origin. Nature 186:402-403, 1960.
27. Bennington JL. Cancer of the kidney - etiology, epidemiology, and pathology. Cancer 32:1017-1029, 1973.
28. Ito N, Hiasa Y, Kamamoto Y, et al. Histological analysis of kidney tumors in rats induced by chemical carcinogenesis. Gann 62:435-444, 1971.
29. Nogueira E, Klimek F, Weber E, Bannasch P. Collecting duct origin of rat renal clear cell tumors. Virchows Archiv B Cell Pathol 57:275-283, 1989.
30. Posten CD, Jaffe GS, Lubensky IA, et al. Characterization of the renal pathology of a familial form of renal cell carcinoma associated with von Hippel-Lindau disease:Clinical and molecular genetic implications. J Urol 153:22-26, 1995.
31. Walker C, Ahn Y-T, Everitt J, Yuan X. Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus. Mol Carcinog 15:154-161, 1996.