Improved Chemical Strategies for the Targeted Therapy of Cancer

Angewandte Chemie - International Edition

Volumn 42, Issue 39, 2003, Pages 4726-4728

  Maison, Wolfgang ^a   Frangioni, John V ^b  

^a UNIVERSITY OF HAMBURG   (Germany)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Antitumor agents; Bifunctional linkers; Chemical conjugation; Peptides; Tumor targeting

Indexed keywords

DRUG THERAPY; MOLECULES; TOXIC MATERIALS;

CYTOTOXIC COMPOUNDS;

TUMORS;

4 HYDROXYMANDELIC ACID; BOMBESIN DERIVATIVE; CALICHEAMICIN; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; GEMTUZUMAB OZOGAMICIN; GONADORELIN DERIVATIVE; IDN 5109; KS 61; KS 77; MANDELIC ACID DERIVATIVE; MONOCLONAL ANTIBODY; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; N SUCCINIMIDYL 4 (2 PYRIDYLDITHIO)PENTANOATE; PACLITAXEL DERIVATIVE; SB T 110131; SOMATOSTATIN DERIVATIVE; TAXANE DERIVATIVE; UNCLASSIFIED DRUG;

CANCER CELL; CANCER THERAPY; CHEMICAL ANALYSIS; CONJUGATE; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG TARGETING; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; REVIEW; TARGET CELL; TISSUE SPECIFICITY;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; BRIDGED COMPOUNDS; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; LIGANDS; MANDELIC ACIDS; NEOPLASMS; OLIGOPEPTIDES; PACLITAXEL; TAXOIDS;

EID: 0142183622     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200301666     Document Type: Review

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