Safety and efficacy of convection-enhanced delivery of gemcitabine or carboplatin in a malignant glioma model in rats

Journal of Neurosurgery

Volumn 99, Issue 5, 2003, Pages 893-898

  Degen, Jeffrey W ^b   Walbridge, Stuart ^b   Vortmeyer, Alexander O ^b   Oldfield, Edward H ^b   Lonser, Russell R ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NONE

Author keywords

Carboplatin; Chemotherapy; Convection enhanced delivery; Gemcitabine; Glioma; Rat

Indexed keywords

CARBOPLATIN; GEMCITABINE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; BRAIN PERFUSION; BRAIN REGION; BRAIN STEM; CANCER CHEMOTHERAPY; CANCER MODEL; CANCER MORTALITY; CANCER REGRESSION; CANCER TRANSPLANTATION; CLINICAL FEATURE; CONTROLLED STUDY; CONVECTION ENHANCED DRUG DELIVERY; CORPUS STRIATUM; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SAFETY; GLIOBLASTOMA; HEMIPARESIS; HISTOPATHOLOGY; KAPLAN MEIER METHOD; LETHARGY; MALE; NONHUMAN; OUTCOMES RESEARCH; PRIORITY JOURNAL; RAT; RAT STRAIN; SEIZURE; SURVIVAL RATE; TECHNIQUE; THERMODYNAMICS; TUMOR VOLUME; WEIGHT REDUCTION;

EID: 0142182636     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.2003.99.5.0893     Document Type: Article

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