Pulmonary Surfactant Protein A, B, and C mRNA and Protein Expression in the Nitrofen-Induced Congenital Diaphragmatic Hernia Rat Model

Pediatric Research

Volumn 54, Issue 5, 2003, Pages 641-652

  Van Tuyl, Minke ^a,b   Blommaart, Pietjan E ^b   Keijzer, Richard ^a   Wert, Susan E ^c   Ruijter, Jan M ^b   Lamers, Wouter H ^b   Tibboel, Dick ^a  

^a SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NITROFEN; SURFACTANT PROTEIN A; SURFACTANT PROTEIN B; SURFACTANT PROTEIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONGENITAL DIAPHRAGM HERNIA; CONTROLLED STUDY; EMBRYO; FEMALE; FETUS; HYPOTHESIS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUNG INSUFFICIENCY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT;

ANIMALS; DISEASE MODELS, ANIMAL; EMBRYO; GESTATIONAL AGE; HERNIA, DIAPHRAGMATIC; HUMANS; IN SITU HYBRIDIZATION; INFANT, NEWBORN; LUNG; PHENYL ETHERS; PULMONARY SURFACTANT-ASSOCIATED PROTEIN A; PULMONARY SURFACTANT-ASSOCIATED PROTEIN B; PULMONARY SURFACTANT-ASSOCIATED PROTEIN C; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 0142179087     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/01.PDR.0000086906.19683.42     Document Type: Article

References (65)

1. Torfs CP, Curry CJ, Bateson TF, Honore LH 1992 A population-based study of congenital diaphragmatic hernia. Teratology 46:555-565
2. Benjamin DR, Juul S, Siebert JR 1988 Congenital posterolateral diaphragmatic hernia: associated malformations. J Pediatr Surg 23:899-903
3. Fauza DO, Wilson JM 1994 Congenital diaphragmatic hernia and associated anomalies: their incidence, identification, and impact on prognosis. J Pediatr Surg 29:1113-1117
4. Tibboel D, Gaag AV 1996 Etiologic and genetic factors in congenital diaphragmatic hernia. Clin Perinatol 23:689-699
5. Thébaud B, Mercier JC, Dinh-Xuan AT 1998 Congenital diaphragmatic hernia. A cause of persistent pulmonary hypertension of the newborn which lacks an effective therapy. Biol Neonate 74:323-336
6. Kays DW, Langham Jr MR, Ledbetter DJ, Talbert JL 1999 Detrimental effects of standard medical therapy in congenital diaphragmatic hernia. Ann Surg 230:340-348
7. Boloker J, Bateman DA, Wung JT, Stolar CJ 2002 Congenital diaphragmatic hernia in 120 infants treated consecutively with permissive hypercapnea/spontaneous respiration/elective repair. J Pediatr Surg 37:357-366
8. Beresford MW, Shaw NJ 2000 Outcome of congenital diaphragmatic hernia, Pediatr Pulmonol 30:249-256
9. IJsselstijn H, Tibboel D 1998 The lungs in congenital diaphragmatic hernia: do we understand? Pediatr Pulmonol 26:204-218
10. van Tuyl M, Hösgor M, Tibboel D 2001 Tracheal ligation and corticosteroids in congenital diaphragmatic hernia: for better for worse? Pediatr Res 50:441-444
11. 1995 Effect of corticosteroids for fetal maturation on perinatal outcomes. NIH Consensus Development Panel on the Effect of Corticosteroids for Fetal Maturation on Perinatal Outcomes JAMA 273:413-418
12. Bolt RJ, van Weissenbruch MM, Lafeber HN, Delemarre-van de Waal HA 2001 Glucocorticoids and lung development in the fetus and preterm infant. Pediatr Pulmonol 32:76-91
13. Soll RF, Morley CJ 2001 Prophylactic versus selective use of surfactant in preventing morbidity and mortality in preterm infants. Cochrane Database Syst Rev 2:CD000510
14. Floros J, Kala P 1998 Surfactant proteins: molecular genetics of neonatal pulmonary diseases, Annu Rev Physiol 60:365-384
15. Haagsman HP, van Golde LM 1991 Synthesis and assembly of lung surfactant. Annu Rev Physiol 53:441-464
16. Zhou H, Morotti RA, Profitt SA, Langston C, Wert SE, Whitsett JA, Greco MA 2001 Expression of thyroid transcription factor-1, surfactant proteins, type I cell-associated antigen, and Clara cell secretory protein in pulmonary hypoplasia. Pediatr Dev Pathol 4:364-371
17. Sullivan KM, Hawgood S, Flake AW, Harrison MR, Adzick NS 1994 Amniotic fluid phospholipid analysis in the fetus with congenital diaphragmatic hernia. J Pediatr Surg 29:1020-1023
18. IJsselstijn H, Zimmermann LJ, Bunt JE, de Jongste JC, Tibboel D 1998 Prospective evaluation of surfactant composition in bronchoalveolar lavage fluid of infants with congenital diaphragmatic hernia and of age-matched controls. Crit Care Med 26:573-580
19. Moya FR, Thomas VL, Romaguera J, Mysore MR, Maberry M, Bernard A, Freund M 1995 Fetal lung maturation in congenital diaphragmatic hernia. Am J Obstet Gynecol 173:1401-1405
20. Asabe K, Tsuji K, Handa N, Kurosaka N, Kajiwara M 1997 Immunohistochemical distribution of surfactant apoprotein-A in congenital diaphragmatic hernia. J Pediatr Surg 32:667-672
21. Sakurai Y, Azarow K, Cutz E, Messineo A, Pearl R, Bohn D 1999 Pulmonary barotrauma in congenital diaphragmatic hernia: a clinicopathological correlation. J Pediatr Surg 34:1813-1817
22. Wilcox DT, Irish MS, Holm BA, Glick PL 1996 Animal models in congenital diaphragmatic hernia. Clin Perinatol 23:813-822
23. Glick PL, Stannard VA, Leach CL, Rossman J, Hosada Y, Morin FC, Cooney DR, Allen JE, Holm B 1992 Pathophysiology of congenital diaphragmatic hernia II: the fetal lamb CDH model is surfactant deficient. J Pediatr Surg 27:382-387
24. Suen HC, Catlin EA, Ryan DP, Wain JC, Donahoe PK 1993 Biochemical immaturity of lungs in congenital diaphragmatic hernia. J Pediatr Surg 28:471-475
25. Brandsma AE, Tibboel D, Vulto IM, Egberts J, Ten Have-Opbroek AA 1993 Ultrastructural features of alveolar epithelial cells in the late fetal pulmonary acinus: a comparison between normal and hypoplastic lungs using a rat model of pulmonary hypoplasia and congenital diaphragmatic hernia. Microsc Res Tech 26:389-399
26. Wilcox DT, Glick PL, Karamanoukian HL, Azizkhan RG, Holm BA 1995 Pathophysiology of congenital diaphragmatic hernia. XII: Amniotic fluid lecithin/sphingomyelin ratio and phosphatidylglycerol concentrations do not predict surfactant status in congenital diaphragmatic hernia. J Pediatr Surg 30:410-412
27. Alfanso LF, Arnaiz A, Alvarez FJ, Qi B, Diez-Pardo JA, Vallis-i-Soler A, Tovar JA 1996 Lung hypoplasia and surfactant system immaturity induced in the fetal rat by prenatal exposure to nitrofen. Biol Neonate 69:94-100
28. Wilcox DT, Glick PL, Karamanoukian HL, Holm BA 1997 Contributions by individual lungs to the surfactant status in congenital diaphragmatic hernia. Pediatr Res 41:686-691
29. Mysore MR, Margraf LR, Jaramillo MA, Breed DR, Chau VL, Arevalo M, Moya FR 1998 Surfactant protein A is decreased in a rat model of congenital diaphragmatic hernia. Am J Respir Crit Care Med 157:654-657
30. Coleman C, Zhao J, Gupta M, Buckley S, Telft JD, Wuenschell CW, Minoo P, Anderson KD, Warburton D 1998 Inhibition of vascular and epithelial differentiation in murine nitrofen-induced diaphragmatic hernia. Am J Physiol 274:L636-L646
31. Losada A, Tovar JA, Xia HM, Diez-Pardo JA, Santisteban P 2000 Down-regulation of thyroid transcription factor-1 gene expression in fetal lung hypoplasia is restored by glucocorticoids Endocrinology 141:2166-2173
32. Benachi A, Chailley-Heu B, Barlier-Mur AM, Dumez Y, Bourbon J 2002 Expression of surfactant proteins and thyroid transcription factor 1 in an ovine model of congenital diaphragmatic hernia. J Pediatr Surg 37:1393-1398
33. Guarino N, Oue T, Shima H, Puri P 2000 Antenatal dexamethasone enhances surfactant protein synthesis in the hypoplastic lung of nitrofen-induced diaphragmatic hernia in rats. J Pediatr Surg 35:1468-1473
34. Shima H, Guarino N, Puri P 2000 Effect of hyperoxia on surfactant protein gene expression in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats. Pediatr Surg Int 16:473-477
35. Guilbert TW, Gebb SA, Shannon JM 2000 Lung hypoplasia in the nitrofen model of congenital diaphragmatic hernia occurs early in development. Am J Physiol Lung Cell Mol Physiol 279:L1159-L1171
36. Bratu I, Flageole H, Laberge JM, Possmayer F, Harbottle R, Kay S, Khalife S, Piedboeuf B 2001 Surfactant levels after reversible tracheal occlusion and prenatal steroids in experimental diaphragmatic hernia. J Pediatr Surg 36:122-127
37. Utsuki T, Hashizume K, Iwamori M 2001 Impaired spreading of surfactant phospholipids in the lungs of newbom rats with pulmonary hypoplasia as a model of congenital diaphragmatic hernia induced by nitrofen. Biochim Biophys Acta 1531:90-98
38. Thébaud B, Barlier-Mur AM, Chailley-Heu B, Henrion-Caude A, Tibboel D, DinhXuan AT, Bourbon JR 2001 Restoring effects of vitamin a on surfactant synthesis in nitrofen-induced congenital diaphragmatic hernia in rats. Am J Respir Crit Care Med 164:1083-1089
39. Valls-i-Soler A, Alfonso LF, Amaiz A, Alvarez FJ, Tovar JA 1996 Pulmonary surfactant dysfunction in congenital diaphragmatic hernia: experimental and clinical findings. Biol Neonate 69:318-326
40. Jonker A, de Boer PA, van den Hoff MJ, Lamers WH, Moorman AF 1997 Towards quantitative in situ hybridization. J Histochem Cytochem 45:413-423
41. Tenbrinck R, Tibboel D, Gaillard JL, Kluth D, Bos AP, Lachmann B, Molenaar JC 1990 Experimentally induced congenital diaphragmatic hernia in rats. J Pediatr Surg 25:426-429
42. Keijzer R, Liu J, Deimling J, Tibboel D, Post M 2000 Dual-hit hypothesis explains pulmonary hypoplasia in the nitrofen model of congenital diaphragmatic hernia. Am J Pathol 156:1299-1306
43. Korfhagen TR, Bruno MD, Glasser SW, Ciraolo PJ, Whitsett JA, Lattier DL, Wikenheiser KA, Clark JC 1992 Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity. Am J Physiol 263:L546-L554
44. D'Amore-Bruno MA, Wikenheiser KA, Carter JE, Clark JC, Whitsett JA 1992 Sequence, ontogeny, and cellular localization of murine surfactant protein B mRNA. Am J Physiol 262:L40-L47
45. Glasser SW, Korfhagen TR, Bruno MD, Dey C, Whitsett JA 1990 Structure and expression of the pulmonary surfactant protein SP-C gene in the mouse. J Biol Chem 265:21986-21991
46. Moorman AF, De Boer PA, Ruijter JM, Hagoort J, Franco D, Lamers WH 2000 Radio-isotopic in situ hybridization on tissue sections. Practical aspects and quantification. Methods Mol Biol 137:97-115
47. Han RN, Buch S, Freeman BA, Post M, Tanswell AK 1992 Platelet-derived growth factor and growth-related genes in rat lung. II. Effect of exposure to 85% 02. Am J Physiol 262:L140-L146
48. Zhou L, Lim L, Costa RH, Whitsett JA 1996 Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung. J Histochem Cytochem 44:1183-1193
49. Pringle KC, Turner JW, Schofield JC, Soper RT 1984 Creation and repair of diaphragmatic hernia in the fetal lamb: lung development and morphology. J Pediatr Surg 19:131-140
50. Brandsma AE, ten Have-Opbroek AA, Vulto IM, Molenaar JC, Tibboel D 1994 Alveolar epithelial composition and architecture of the late fetal pulmonary acinus: an immunocytochemical and morphometric study in a rat model of pulmonary hypoplasia and congenital diaphragmatic hernia. Exp Lung Res 20:491-515
51. Janssen DJ, Tibboel D, Camielli VP, van Emmen E, Luijendijk IH, Wattimena JL, Zimmermann LJ 2003 Surfactant phosphatidylcholine pool size in human neonates with congenital diaphragmatic hernia requiring ECMO. J Pediatr 142:247-252
52. Cogo PE, Zimmermann LJ, Rosso F, Tormena F, Gamba P, Verlato G, Baritussio A, Carnielli VP 2002 Surfactant synthesis and kinetics in infants with congenital diaphragmatic hernia. Am J Respir Crit Care Med 166:154-158
53. Bohn D 2002 Congenital diaphragmatic hernia. Am J Respir Crit Care Med 166:911-915
54. Ruijter JM, Hagoort J, De Boer PA, Moorman AF 2001 Calibration of densitometry in radio-isotopic in situ hybridization. Image Anal Stereol 20:219-224
55. Moorman AF, Schumacher CA, de Boer PA, Hagoort J, Bezstarosti K, van den Hoff MJ, Wagenaar GT, Lamers JM, Wuytack F, Christoffels VM, Fiolet JW 2000 Presence of functional sarcoplasmic reticulum in the developing heart and its confinement to chamber myocardium. Dev Biol 223:279-290
56. Schellhase DE, Emrie PA, Fisher JH, Shannon JM 1989 Ontogeny of surfactant apoproteins in the rat. Pediatr Res 26:167-174
57. Losty PD, Pacheco BA, Manganaro TF, Donahoe PK, Jones RC, Schnitzer JJ 1996 Prenatal hormonal therapy improves pulmonary morphology in rats with congenital diaphragmatic hernia. J Surg Res 65:42-52
58. Kitterman JA, Chapin CJ, Vanderbilt JN, Porta NF, Scavo LM, Dobbs LG, Ertsey R, Goerke J 2002 Effects of oligohydramnios on lung growth and maturation in the fetal rat. Am J Physiol Lung Cell Mol Physiol 282:L431-L439
59. Suen HC, Bloch KD, Donahoe PK 1994 Antenatal glucocorticoid corrects pulmonary immaturity in experimentally induced congenital diaphragmatic hernia in rats. Pediatr Res 35:523-529
60. Hedrick HL, Kaban JM, Pacheco BA, Losty PD, Doody DP, Ryan DP, Manganaro TF, Donahoe PK, Schnitzer JJ 1997 Prenatal glucocorticoids improve pulmonary morphometrics in fetal sheep with congenital diaphragmatic hernia. J Pediatr Surg 32:217-221
61. IJsselstijn H, Pacheco BA, Albert A, Sluiter W, Donahoe PK, De Jongste JC, Schnitzer JJ, Tibboel D 1997 Prenatal hormones alter antioxidant enzymes and lung histology in rats with congenital diaphragmatic hernia. Am J Physiol 272:L1059-L1065
62. Kapur P, Holm BA, Irish MS, Sokolowski J, Patel A, Glick PL 1999 Lung physiological and metabolic changes in lambs with congenital diaphragmatic hernia after administration of prenatal maternal corticosteroids. J Pediatr Surg 34:354-356
63. Bos AP, Tibboel D, Hazebroek FW, Molenaar JC, Lachmann B, Gommers D 1991 Surfactant replacement therapy in high-risk congenital diaphragmatic hernia. Lancet 338:1279
64. Glick PL, Leach CL, Besner GE, Egan EA, Morin FC, Malanowska-Kantoch A, Robinson LK, Brody A, Lele AS, McDonnell M, Holm B, Rodgers BT, Msall ME, Courey NG, Karp MP, Allen JE, Jewett Jr TC, Cooney DR 1992 Pathophysiology of congenital diaphragmatic hernia. III: Exogenous surfactant therapy for the high-risk neonate with CDH. J Pediatr Surg 27:866-869
65. Lotze A, Knight GR, Anderson KD, Hull WM, Whitsett JA, O'Donnell RM, Martin G, Bulas DI, Short BL 1994 Surfactant (beractant) therapy for infants with congenital diaphragmatic hernia on ECMO: evidence of persistent surfactant deficiency. J Pediatr Surg 29:407-412