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1
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0033919896
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-
For recent reports involving 2,3-dihydro-1,4-benzodioxin derivatives, see: (a) Czompa, A.; Dinya, Z.; Antus, S.; Varga, Z. Arch. Pharm. 2000, 333, 175-180; (b) Gu, W. X.; Jing, X. B.; Pan, X. F.; Chan, A. S. C.; Yang, T. K. Tetrahedron Lett. 2000, 41, 6079-6082; (c) Ward, R. S. Nat. Prod. Rep. 1999, 16, 75-96; (d) Bolognesi, M. L.; Budriesi, R.; Cavalli, A.; Chiarini, A.; Gotti, R.; Leonardi, A.; Minarini, A.; Poggesi, E.; Recanatini, M.; Rosini, M.; Tumiatti, V.; Melchiorre, C. J. Med. Chem. 1999, 42, 4214-4224; (d) Guillaumet, G. In Comprehensive Heterocyclic Chemistry II, 1st ed.; Katrizky, A. R.; Rees, C. W.; Scriven, E. F. V., Eds.; Pergamon: Oxford, 1996; Vol. 6, pp. 447-463.
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Czompa, A.1
Dinya, Z.2
Antus, S.3
Varga, Z.4
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2
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0034609172
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For recent reports involving 2,3-dihydro-1,4-benzodioxin derivatives, see: (a) Czompa, A.; Dinya, Z.; Antus, S.; Varga, Z. Arch. Pharm. 2000, 333, 175-180; (b) Gu, W. X.; Jing, X. B.; Pan, X. F.; Chan, A. S. C.; Yang, T. K. Tetrahedron Lett. 2000, 41, 6079-6082; (c) Ward, R. S. Nat. Prod. Rep. 1999, 16, 75-96; (d) Bolognesi, M. L.; Budriesi, R.; Cavalli, A.; Chiarini, A.; Gotti, R.; Leonardi, A.; Minarini, A.; Poggesi, E.; Recanatini, M.; Rosini, M.; Tumiatti, V.; Melchiorre, C. J. Med. Chem. 1999, 42, 4214-4224; (d) Guillaumet, G. In Comprehensive Heterocyclic Chemistry II, 1st ed.; Katrizky, A. R.; Rees, C. W.; Scriven, E. F. V., Eds.; Pergamon: Oxford, 1996; Vol. 6, pp. 447-463.
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Tetrahedron Lett.
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, pp. 6079-6082
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Gu, W.X.1
Jing, X.B.2
Pan, X.F.3
Chan, A.S.C.4
Yang, T.K.5
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3
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0033083666
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-
For recent reports involving 2,3-dihydro-1,4-benzodioxin derivatives, see: (a) Czompa, A.; Dinya, Z.; Antus, S.; Varga, Z. Arch. Pharm. 2000, 333, 175-180; (b) Gu, W. X.; Jing, X. B.; Pan, X. F.; Chan, A. S. C.; Yang, T. K. Tetrahedron Lett. 2000, 41, 6079-6082; (c) Ward, R. S. Nat. Prod. Rep. 1999, 16, 75-96; (d) Bolognesi, M. L.; Budriesi, R.; Cavalli, A.; Chiarini, A.; Gotti, R.; Leonardi, A.; Minarini, A.; Poggesi, E.; Recanatini, M.; Rosini, M.; Tumiatti, V.; Melchiorre, C. J. Med. Chem. 1999, 42, 4214-4224; (d) Guillaumet, G. In Comprehensive Heterocyclic Chemistry II, 1st ed.; Katrizky, A. R.; Rees, C. W.; Scriven, E. F. V., Eds.; Pergamon: Oxford, 1996; Vol. 6, pp. 447-463.
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, pp. 75-96
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Ward, R.S.1
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4
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0033533802
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For recent reports involving 2,3-dihydro-1,4-benzodioxin derivatives, see: (a) Czompa, A.; Dinya, Z.; Antus, S.; Varga, Z. Arch. Pharm. 2000, 333, 175-180; (b) Gu, W. X.; Jing, X. B.; Pan, X. F.; Chan, A. S. C.; Yang, T. K. Tetrahedron Lett. 2000, 41, 6079-6082; (c) Ward, R. S. Nat. Prod. Rep. 1999, 16, 75-96; (d) Bolognesi, M. L.; Budriesi, R.; Cavalli, A.; Chiarini, A.; Gotti, R.; Leonardi, A.; Minarini, A.; Poggesi, E.; Recanatini, M.; Rosini, M.; Tumiatti, V.; Melchiorre, C. J. Med. Chem. 1999, 42, 4214-4224; (d) Guillaumet, G. In Comprehensive Heterocyclic Chemistry II, 1st ed.; Katrizky, A. R.; Rees, C. W.; Scriven, E. F. V., Eds.; Pergamon: Oxford, 1996; Vol. 6, pp. 447-463.
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Bolognesi, M.L.1
Budriesi, R.2
Cavalli, A.3
Chiarini, A.4
Gotti, R.5
Leonardi, A.6
Minarini, A.7
Poggesi, E.8
Recanatini, M.9
Rosini, M.10
Tumiatti, V.11
Melchiorre, C.12
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5
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84944045237
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Katrizky, A. R.; Rees, C. W.; Scriven, E. F. V., Eds.; Pergamon: Oxford
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For recent reports involving 2,3-dihydro-1,4-benzodioxin derivatives, see: (a) Czompa, A.; Dinya, Z.; Antus, S.; Varga, Z. Arch. Pharm. 2000, 333, 175-180; (b) Gu, W. X.; Jing, X. B.; Pan, X. F.; Chan, A. S. C.; Yang, T. K. Tetrahedron Lett. 2000, 41, 6079-6082; (c) Ward, R. S. Nat. Prod. Rep. 1999, 16, 75-96; (d) Bolognesi, M. L.; Budriesi, R.; Cavalli, A.; Chiarini, A.; Gotti, R.; Leonardi, A.; Minarini, A.; Poggesi, E.; Recanatini, M.; Rosini, M.; Tumiatti, V.; Melchiorre, C. J. Med. Chem. 1999, 42, 4214-4224; (d) Guillaumet, G. In Comprehensive Heterocyclic Chemistry II, 1st ed.; Katrizky, A. R.; Rees, C. W.; Scriven, E. F. V., Eds.; Pergamon: Oxford, 1996; Vol. 6, pp. 447-463.
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14
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85030972042
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note
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When the reaction was tried using NaH in DMF at room temperature or sodium methoxide in MeOH both, at room temperature and under reflux only starting material was recovered unaltered.
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15
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85030972349
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note
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2/MeOH (25/1).
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16
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85030972246
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note
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Longer reaction times afforded mainly decomposition.
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17
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85030966824
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note
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+: 154.
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18
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0023837327
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Demerseman P., Kiffer D., Debussche L., Lion C., Royer R., Sentenac-Roumanou H. Eur. J. Med. Chem. 23:1988;63-68.
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(1988)
Eur. J. Med. Chem.
, vol.23
, pp. 63-68
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Demerseman, P.1
Kiffer, D.2
Debussche, L.3
Lion, C.4
Royer, R.5
Sentenac-Roumanou, H.6
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20
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85030968224
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note
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2/acetone (9/1 and 4/1).
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21
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85030959852
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note
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+: 166.
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-
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23
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85030972416
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note
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2/acetone (9/1), to remove Lawesson's reagent by-products obtained in the course of the reaction and the second one, eluted with hexane/acetone (9/1), to obtain the pure compound.
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25
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85030954122
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note
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+: 184.
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27
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85030962699
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3 or NaH, no reaction took place.
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3 or NaH, no reaction took place.
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28
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85030968108
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note
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+: 181.
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