Three-dimensional reconstruction of thin filaments containing mutant tropomyosin

Biophysical Journal

Volumn 78, Issue 2, 2000, Pages 908-917

  Rosol, M ^a   Lehman, William ^a   Craig, R ^b   Landis, C ^c   Butters, C ^c   Tobacman, L S ^c  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; CALCIUM ION; MUTANT PROTEIN; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN SUBFRAGMENT 1; N ETHYLMALEIMIDE; TROPOMYOSIN; TROPONIN;

ACTIN MYOSIN INTERACTION; ALLOSTERISM; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DELETION MUTANT; ELECTRON MICROSCOPY; NONHUMAN; PROTEIN BINDING; THIN FILAMENT; THREE DIMENSIONAL IMAGING;

ANIMALIA;

EID: 0034087156     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(00)76648-3     Document Type: Article

References (56)

1. Amos, L. A., and A. Klug. 1975. Three-dimensional image reconstruction of the contractile tail of T4 bacteriophage. J. Mol. Biol. 99:51-73.
2. Bremel, R. D., J. M. Murray, and A. Weber. 1972. Manifestations of cooperative behavior in the regulated actin filament during actin-activated ATP hydrolysis in the presence of calcium. Cold Spring Harb. Symp. Quant. Biol. 37:267-275.
3. Cassell, M., and L. S. Tobacman. 1996. Opposite effects of myosin subfragment 1 on binding of cardiac troponin and tropomyosin to the thin filament. J. Biol. Chem. 271:12867-12872.
4. Coates, J. H., A. H. Criddle, and M. A. Geeves. 1985. Pressure-relaxation studies of pyrene-labeled actin and myosin subfragment 1 from rabbit skeletal muscle. Evidence for two states of actin-subfragment 1. Biochem. J. 232:351-356.
5. Cohen, I., and C. Cohen. 1972. A tropomyosin-like protein from human platelets. J. Mol. Biol. 68:383-387.
6. Criddle, A. H., M. A. Geeves, M. A., and T. Jeffries. 1985. The use of actin labeled with N-(l-pyrenyl)iodoacetamide to study the interaction of actin with myosin subfragments and troponin/tropomyosin. Biochem. J. 232:343-349.
7. DeRosier, D. J., and P. B. Moore. 1970. Reconstruction of three-dimensional images from electron micrographs of structures with helical symmetry. J. Mol. Biol. 52:355-369.
8. Eaton, B. L. 1976. Tropomyosin binding to F-actin induced by myosin heads. Science. 192:1337-1339.
9. Egelman, E. H. 1986. An algorithm for straightening images of curved filamentous structures. Ultramicroscopy. 19:367-374.
10. Flicker, P. F., G. N. Phillips, and C. Cohen. 1982. Troponin and its interactions with tropomyosin. An electron microscope study. J. Mol. Biol. 162:495-501.
11. Geeves, M. A., and D. J. Halsall. 1986. The dynamics of the interaction between myosin subfragment 1 and pyrene-labeled thin filaments from rabbit skeletal muscle. Proc. R. Soc. Lond. B. 229:85-95.
12. Haselgrove, J. C. 1972. X-ray evidence for a conformational change in actin-containing filaments of vertebrate striated muscle. Cold Spring Harb. Symp. Quant. Biol. 37:341-352.
13. Hill, L. E., J. P. Mehegan, C. A. Butters, and L. S. Tobacman. 1992. Analysis of troponin-tropomyosin binding to actin. Troponin does not promote interactions between tropomyosin molecules. J. Biol. Chem. 267:16106-16113.
14. Hill, T. L., E. Eisenberg, and L. E. Greene. 1980. Theoretical model for the cooperative equilibrium binding of myosin subfragment 1 to actin-troponin-tropomyosin complex. Proc. Natl. Acad. Sci. USA. 77: 3186-3190.
15. Hitchcock-DeGregori, S. E., and Y. An. 1996. Integral repeats and a continuous coiled coil are required for binding of striated tropomyosin to the regulated thin filament. J. Biol. Chem. 271:3600-3603.
16. Hitchcock-DeGregori, S. E., and T. A. Varnell. 1990. Tropomyosin has discrete actin binding sites with sevenfold and fourteenfold periodicities. J. Mol. Biol. 214:885-896.
17. Holmes, K. C. 1995. The actomyosin interaction and its control by tropomyosin. Biophys. J. 68(Suppl.):2-7.
18. Huxley, H. E. 1972. Structural changes in actin-and myosin-containing filaments during contraction. Cold Spring Harb. Symp. Quant. Biol. 37:361-376.
19. Jones, T. A., J. Y. Zou, S. W. Cowan, and M. Kjeldgaard. 1991. Improved methods for the building of protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A. 47:110-119.
20. Landis, C. A., N. Back, E. Homsher, and L. S. Tobacman. 1999. Effects of tropomyosin internal deletions on thin filament function. J. Biol. Chem. 274:31279-31285.
21. Landis, C. A., A. Bobkova, E. Homsher, and L. S. Tobacman. 1997. The active state of the thin filament is destabilized by an internal deletion in tropomyosin. J. Biol. Chem. 272:14051-14056.
22. 2--induced tropomyosin movement in Limulus thin filaments revealed by three-dimensional reconstruction. Nature. 368:65-67.
23. Lehman, W., P. Vibert, P. Uman, and R. Craig. 1995. Steric-blocking by tropomyosin visualized in relaxed vertebrate muscle thin filaments. J. Mol. Biol. 251:191-196.
24. 2+ or myosin heads? J. Muscle Res. Cell Motil. 15:232-236.
25. Lehrer, S. S., and M. A. Geeves. 1998. The muscle thin filament as a classical cooperative/allosteric regulatory system. J. Mol. Biol. 277: 1081-1089.
26. Lehrer, S. S., and E. P. Morris. 1982. Dual effects of tropomyosin and troponin-tropomyosin on subfragment 1 ATPase. J. Biol. Chem. 257: 8073-8080.
27. Lin, D., A. Bobkova, E. Homsher, and L. S. Tobacman. 1996. Altered cardiac troponin T in vitro function in the presence of a mutation implicated in familial hypertrophic cardiomyopathy. J. Clin. Invest. 97:2842-2848.
28. Lorenz, M., K. J. V. Poole, D. Popp, G. Rosenbaum, and K. C. Holmes. 1995. An atomic model of the unregulated thin filament obtained by x-ray fiber diffraction on oriented actin-tropomyosin gels. J. Mol. Biol. 246:108-119.
29. Lorenz, M., D. Popp, and K. C. Holmes. 1993. Refinement of the F-actin model against x-ray fiber diffraction data by use of a directed mutation algorithm. J. Mol. Biol. 234:826-836.
30. McGough, A., and M. Way. 1995. Molecular model of an actin filament capped by a severing protein. J. Struct. Biol. 115:144-150.
31. McKillop, D. F. A., and M. A. Geeves. 1993. Regulation of the interaction between actin and myosin subfragment-1: evidence for three states of the thin filament. Biophys. J. 65:693-701.
32. McLachlan, A. D., and M. Stewart. 1976. The 14-fold periodicity in α-tropomyosin and the interaction with actin. J. Mol. Biol. 103:271-298.
33. Miller, C. J., P. Cheung, P. White, and E. Reisler. 1995. Actin's view of the actomyosin interface. Biophys. J. 68(Suppl.):50-56.
34. Milligan, R. A., and P. F. Flicker. 1987. Structural relationships of actin, myosin, and tropomyosin revealed by cryo-electron microscopy. J. Cell Biol. 105:29-39.
35. Milligan, R. A., M. Whittaker, and D. Safer. 1990. Molecular structure of F-actin and the location of surface binding sites. Nature. 348:217-221.
36. Monteiro, P. B., R. C. Lataro, J. A. Ferro, and F. C. Reinach. 1994. Functional alpha-tropomyosin produced in Escherichia coli. A dipeptide extension can substitute for the amino-terminal acetyl group. J. Biol. Chem. 269:10461-10466.
37. Moody, C., W. Lehman, and R. Craig. 1990. Caldesmon and the structure of vertebrate smooth muscle thin filaments: electron microscopy of isolated thin filaments. J. Muscle Res. Cell Motil. 11:176-185.
38. Murray, J. M., M. K. Knox, C. E. Trueblood, and A. Weber. 1982. Potentiated state of the tropomyosin actin filament and nucleotide-containing myosin subfragment 1. Biochemistry. 21:906-915.
39. Murray, J. M., and A. Weber. 1973. Molecular control mechanisms in muscle contraction. Physiol. Rev. 53:612-673.
40. Owen, C., D. G. Morgan, and D. J. DeRosier. 1996. Image analysis of helical objects: the Brandeis helical package. J. Struct. Biol. 116: 167-175.
41. Parry, D. A. D., and J. M. Squire. 1973. Structural role of tropomyosin in muscle regulation: analysis of x-ray patterns from relaxed and contracting muscles. J. Mol. Biol. 75:33-55.
42. Pemrick, S., and A. Weber. 1976. Mechanism of inhibition by N-ethylmaleimide treatment of myosin. Biochemistry. 15:5193-5198.
43. Phillips, G. N., J. P. Fillers, and C. Cohen. 1986. Tropomyosin crystal structure and muscle regulation. J. Mol. Biol. 192:111-131.
44. Poole, K. V. G., G. Evans, G. Rosenbaum, M. Lorenz, and K. C. Holmes. 1995. The effect of cross-bridges on the calcium sensitivity of the structural change of the regulated thin filament. Biophys. J. 68:365a (Abstr.).
45. Rayment, I., H. M. Holden, M. Whittaker, C. B. Yohn, M. Lorenz, K. C. Holmes, and R. A. Milligan. 1993. Structure of the actin-myosin complex and its implications for muscle contraction. Science. 261:58-65.
46. Spudich, J. A., and S. Watt. 1971. The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. J. Biol. Chem. 242:4866-4871.
47. Szczesna, D., Y. S. Borovikov, and A. Sobieszek. 1989. Interaction of tropomyosin with F-actin-heavy meromyosin complex. Biol. Chem. Hoppe-Seyler. 370:399-407.
48. Tobacman, L. S., and R. S. Adelstein. 1986. Mechanism of regulation of cardiac actin-myosin subfragment 1 by troponin-tropomyosin. Biochemistry. 25:798-802.
49. Trachtenberg, S., and D. J. DeRosier. 1987. Three-dimensional structure of the frozen-hydrated flagellar filament: the left-handed filament of Salmonella typhimurium. J. Mol. Biol. 195:581-601.
50. Vibert, P., R. Craig, and W. Lehman. 1993. Three-dimensional reconstruction of caldesmon-containing smooth muscle thin filaments. J. Cell Biol. 123:313-321.
51. Vibert, P., R. Craig, and W. Lehman. 1997. Steric-model for activation of muscle thin filaments. J. Mol. Biol. 266:8-14.
52. Weeds, A. G., and R. S. Taylor. 1975. Separation of subfragment-1 isoenzymes from rabbit skeletal muscle myosin. Nature. 257:54-56.
53. Willadsen, K. A., C. A. Butters, L. E. Hill, and L. S. Tobacman. 1992. Effects of the ammo-terminal regions of tropomyosin and troponin T on thin filament assembly. J. Biol. Chem. 267:23746-23752.
54. Williams, D. L., and L. E. Greene. 1983. Comparison of the effects of tropomyosin and troponin-tropomyosin on binding of myosin subfragment 1 to actin. Biochemistry. 22:2770-2774.
55. Williams, D. L., L. E. Greene, and E. Eisenberg. 1988. Cooperative turning on of myosin subfragment 1 adenosine triphosphatase activity by the troponin-tropomyosin complex. Biochemistry. 27:6987-6993.
56. Xu, C., R. Craig, L. Tobacman, R. Horowitz, and W. Lehman. 1999. Tropomyosin positions in regulated thin filaments revealed by cryoelectron microscopy. Biophys. J. 77:985-992.