Parenteral administration of glipizide sodium salt, an inhibitor of adenosine triphosphate-sensitive potassium channels, prolongs short-term survival after severe controlled hemorrhage in rats

Critical Care Medicine

Volumn 31, Issue 10, 2003, Pages 2429-2436

  Evgenov, Oleg V ^a,b   Pacher, Pál ^a,c   Williams, William ^a   Evgenov, Natalia V ^b   Mabley, Jon G ^a   Cicila, James ^a   Sikó, Zsombor B ^a   Salzman, Andrew L ^a   Szabó, Csaba ^a,d  

^a INOTEK CORPORATION   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c SEMMELWEIS UNIVERSITY   (Hungary)

^d RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Adenosine triphosphate sensitive potassium channels; Hemorrhage; Mean arterial pressure; Resuscitation; Shock; Survival

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALANINE AMINOTRANSFERASE; AMYLASE; CREATININE; GLIPIZIDE; GLUCOSE; LACTIC ACID; POTASSIUM CHANNEL BLOCKING AGENT;

AMYLASE BLOOD LEVEL; ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOSE RESPONSE; DRUG MEGADOSE; GLUCOSE BLOOD LEVEL; LACTATE BLOOD LEVEL; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; RAT; SHOCK; WAKEFULNESS;

ADENOSINE TRIPHOSPHATE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLIPIZIDE; HEMODYNAMIC PROCESSES; HEMORRHAGE; HYPOGLYCEMIC AGENTS; INFUSIONS, PARENTERAL; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAVENOUS; MALE; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0142120387     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000089639.84344.A7     Document Type: Article

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