Inhibition of cocaine binding to the human dopamine transporter by a single chain anti-idiotypic antibody: Its cloning, expression, and functional properties

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1638, Issue 3, 2003, Pages 257-266

  Ho, Mitchell ^a,b   Segre, Mariangela ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Anti idiotypic antibody; Antigen mimicry; Cocaine; Cocaine analog; Dopamine transporter; scFv; Single chain antibody

Indexed keywords

ANTIIDIOTYPIC ANTIBODY; COCAINE; DOPAMINE TRANSPORTER; LIGAND; RECEPTOR; CARRIER PROTEIN; IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN FV; MAB K2 3F SCFV ANTIBODY; MAB K2-3F SCFV ANTIBODY; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; NERVE PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DATA ANALYSIS; DOPAMINE UPTAKE; DRUG BINDING; ESCHERICHIA COLI; HUMAN; IN VIVO STUDY; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ANTIBODY AFFINITY; ANTIBODY COMBINING SITE; BIOSYNTHESIS; CHEMICAL STRUCTURE; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

AMINO ACID SEQUENCE; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; BINDING SITES, ANTIBODY; CHROMATOGRAPHY, AFFINITY; CLONING, MOLECULAR; COCAINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; HUMANS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; MASS SPECTROMETRY; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PROTEIN BINDING;

EID: 0142107346     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4439(03)00091-7     Document Type: Article

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