The dopamine transporter carboxyl-terminal tail. Truncation/substitution mutants selectively confer high affinity dopamine uptake while attenuating recognition of the ligand binding domain

Journal of Biological Chemistry

Volumn 271, Issue 34, 1996, Pages 20885-20894

  Lee, Frank J S ^b,d   Pristupa, Zdenek B ^a,d   Ciliax, Brian J ^c   Levey, Allan I ^c   Niznik, Hyman B ^a,b,d,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^e ONTARIO MINISTRY OF HEALTH AND LONG TERM CARE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; AMFEBUTAMONE; AMFONELIC ACID; AMPHETAMINE; COCAINE; DICLOFENSINE; DOPAMINE; INDATRALINE; MAZINDOL; METHYLPHENIDATE; NOMIFENSINE; NORADRENALIN; PHORBOL 13 ACETATE 12 MYRISTATE; SEROTONIN; TRITIUM; VANOXERINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CARBOXY TERMINAL SEQUENCE; DOPAMINE UPTAKE; DOPAMINERGIC SYSTEM; GENE EXPRESSION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; BINDING SITES; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COCAINE; DNA PRIMERS; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; LIGANDS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; TRITIUM;

EID: 0029786334     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.34.20885     Document Type: Article

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