Enhancement and inhibition by 2′-O-hydroxyethyl residues of gene targeting mediated by triple helix forming oligonucleotides

Nucleosides, Nucleotides and Nucleic Acids

Volumn 22, Issue 10, 2003, Pages 1927-1938

  Kundu, Mrinalkanti ^a   Nagatsugi, Fumi ^a   Majumdar, Alokes ^a   Miller, Paul S ^b   Seidman, Michael M ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Bioactivity; Oligonucleotides; Ribose analogue; Triple helix

Indexed keywords

2' O HYDROXYETHYL DERIVATIVE; BASE; CARBOHYDRATE DERIVATIVE; HYDROXYL GROUP; OLIGONUCLEOTIDE; PSORALEN; PYRIMIDINE; REAGENT; UNCLASSIFIED DRUG;

ADDITION REACTION; ANIMAL CELL; ARTICLE; CHEMICAL BINDING; CHO CELL; CONJUGATE; CONTROLLED STUDY; GENE SEQUENCE; GENE TARGETING; GENE THERAPY; GENETIC MANIPULATION; KNOCKOUT GENE; MAMMAL CELL; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PREDICTION; PROTEIN CONFORMATION; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SUBSTITUTION REACTION; TECHNIQUE; TRIPLE HELIX;

ANIMALS; BASE SEQUENCE; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; DNA; GENE TARGETING; HYDROXYLATION; MOLECULAR STRUCTURE; NUCLEIC ACID DENATURATION; OLIGONUCLEOTIDES; THIOGUANINE;

ANIMALIA; CRICETINAE; MAMMALIA;

EID: 0142106866     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120025240     Document Type: Article

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