Simultaneous determination of losartan and EXP3174 in human plasma and urine utilizing liquid chromatography/tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 33, Issue 1, 2003, Pages 73-84

  Polinko, Michelle ^a   Riffel, Kerry ^a   Song, Hengchang ^a   Lo, Man Wai ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

EXP3174; Human plasma and urine; LC MS MS; Losartan; Pediatric

Indexed keywords

2 BUTYL 4 CHLORO 1 [[2' (1H TETRAZOL 5 YL) 4 BIPHENYLYL]METHYL] 5 IMIDAZOLECARBOXYLIC ACID; DRUG METABOLITE; LOSARTAN;

ACCURACY; ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG URINE LEVEL; HUMAN; INTERMETHOD COMPARISON; LINEAR SYSTEM; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETER; PLASMA; PRIORITY JOURNAL; PROCESS DEVELOPMENT; RELIABILITY; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY; URINALYSIS; VALIDATION PROCESS;

EID: 0142092612     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(03)00348-0     Document Type: Article

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