Action of Bauhinia bauhinioides synthetic peptides on serine proteinases

Biochemical and Biophysical Research Communications

Volumn 311, Issue 1, 2003, Pages 241-245

  Cagliari, Cristina I ^a   De Caroli, Fernanda P ^a   Nakahata, Adriana M ^a   Araújo, Mariana S ^a   Nakaie, Clovis R ^a   Sampaio, Misako U ^a   Sampaio, Claudio A M ^a   Oliva, Maria Luiza V ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Bauhinia bauhinioides; Kallikrein; Kunitz inhibitor; Peptides; Plant inhibitor; Primary structure; Serine proteinase; Tissue kallikrein

Indexed keywords

ARGINYLPROLYLGLYCYLLEUCYLPROLYLVALYLARGINYLPHENYLALANYLGLUTAMYLSERYLPROLYLL EUCINAMIDE; ARGINYLPROLYLGLYCYLLEUCYLPROLYLVALYLARGINYLPHENYLALANYLGLUTAMYLSERYLPROLYLL EUCYLARGINYLISOLEUCYLASPARAGINYLISOLEUCYLISOLEUCYLLYSYLGLUTAMINAMIDE; BAUHINIA BAUHINIOIDES EXTRACT; BLOOD CLOTTING FACTOR 10A; GLYCYLLEUCYLPROLYLVALYLARGINYLPHENYLALANYLGLUTAMYLSERINAMIDE; KALLIKREIN INHIBITOR; PLANT EXTRACT; SERINE PROTEINASE INHIBITOR; THROMBIN; TRYPSIN; UNCLASSIFIED DRUG;

ARTICLE; BAUHINIA BAUHINOIDES; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; HUMAN; IC 50; INCUBATION TIME; MEDICINAL PLANT; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SOLID STATE;

BAUHINIA; BAUHINIA BAUHINIOIDES;

EID: 0142090790     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.09.203     Document Type: Article

References (19)

1. Oliva M.L.V., Souza-Pinto J.C., Batista I.F.C., Araújo M.S., Silveira V.F., Auerswald E.A., Mentele R., Eckerskorn C., Sampaio M.U., Sampaio C.A.M. Leucaena leucocephala serine proteinase inhibitor: primary structure and action on blood coagulation, kinin release and rat paw edema. Biochim. Biophys. Acta. 1477:2000;64-74.
2. Andreasen P.A., Engelund R., Petersen H.H. The plasminogen activation system in tumor growth, invasion, and metastasis. Cell. Mol. Life Sci. 20:2000;25-40.
3. Cassim B., Mogy G., Bhoola K.D. Kallikrein cascade and cytokines in inflamed joints. Pharmacol. Ther. 94:2002;1-34.
4. Schmaier A.H. Plasma kallikrein/kinin system: a revised hypothesis for its activation and its physiologic contributions. Curr. Opin. Hematol. 7:2000;261-265.
5. Pesquero J.B., Bader M. Molecular biology of the kallikrein-kinin system: from structure to function. Braz. J. Med. Biol. Res. 31:1998;1197-1203.
6. Wilczynska M., Fa M., Ohlsson P.I., Ny T. The inhibition mechanisms of Serpins. J. Biol. Chem. 270:1995;29652-29655.
7. Olson S.T., Bock P.E., Kvassman J., Shore J.D., Lawrence D.A., Ginsburg D., Bjork I. Role of the catalytic serine in the interactions of serine proteinases with protein inhibitors of the serpin family: contribution of a covalent interaction to the binding energy of serpin-proteinase complexes. J. Biol. Chem. 15:1995;30007.
8. Djie M.Z., Le Bonniec B.F., Hopkins P.C., Hipler K., Stone S.R. Role of the P2 residue in determining the specificity of serpins. Biochemistry. 35:1996;11461-11469.
9. Zahedi R., MacFarlane R.C., Wisnieki J.J., Davis A.E. C1 inhibitor: analysis of the role of amino acid residues within the reactive center loop in target protease recognition. J. Immunol. 167:2001;1500-1506.
10. Richardson M. Seed storage proteins: the enzyme inhibitors. Methods Plant Biochem. 5:1991;259-350.
11. Macedo M.L.R., De Matos D.G., Machado O.L., Marangoni S., Novello J.C. Trypsin inhibitor from Dimorphandra mollis seeds: purification and properties. Phytochemistry. 54:2000;553-558.
12. Oliva M.L.V., Santomauro-Vaz E.M., Andrade S.A., Juliano M.A., Pott V.J., Sampaio M.U., Sampaio C.A.M. Synthetic peptides and fluorogenic substrates related to the reactive site sequence of Kunitz- type inhibitors isolated from Bauhinia: interaction with human plasma kallikrein. Biol. Chem. 382:2001;109-113.
13. Oliva M.L.V., Mendes C.R., Santomauro-Vaz E.M., Juliano M.A., Mentele R., Auerswald E.A., Sampaio M.U., Sampaio C.A.M. Bauhinia bauhinioides plasma kallikrein inhibitor: interaction with synthetic peptides and fluorogenic peptide substrates related to the reactive site sequence. Curr. Med. Chem. 8:2001;977-984.
14. Sampaio C.A.M., Oliva M.L.V., Sampaio M.U., Batista I.F.C., Bueno N.R., Tanaka A.S., Auerswald E.A., Fritz H. Plant serine proteinase inhibitors. Structure and biochemical applications on plasma kallikrein and related enzymes. Immunopharmacology. 32:1996;62-66.
15. Andrade S.A., Santomauro-Vaz E.M., Lopes A.R., Chudzinski-Tavassi A.M., Juliano M.A., Terra W.R., Sampaio M.U., Sampaio C.A.M., Oliva M.L.V. Bauhinia proteinase inhibitor-based synthetic fluorogenic substrates for enzymes isolated from insect midgut and caterpillar bristles. Biol. Chem. 384:2003;489-492.
16. Oliva M.L.V., Andrade S.A., Juliano M.A., Juliano L., Sampaio M.U., Sampaio C.A.M. Kinetic characterization of factor Xa binding using a quenched fluorescent substrate based on the reactive sito of factor Xa inhibitor from Bauhinia ungulata seeds. Curr. Med. Chem. 10:2003;1085-1093.
17. Oliva M.L.V., Andrade S.A., Batista I.F.C., Sampaio M.U., Juliano M., Fritz H., Auerswld E.A., Sampaio C.A.M. Human plasma kallikrein and tissue kallikrein binding to a substrate based on the reactive site of a factor Xa inhibitor isolated from Bauhinia ungulata seeds. Immunopharmacology. 45:1999;145-149.
18. Oliva M.L.V., Grisolia D., Sampaio M.U., Sampaio C.A.M. Properties of highly purified human plasma kallikrein. Agents Actions. 9:1982;52.
19. Araujo M.S., Andreotti R., Tiaen M., Nunes V., Oliva M.L.V., Sampaio M.U., Iimura O., Shimamoto K., Ura N., Sampaio C.A.M. Caiman Crocodilus yacare plasma kininogen detection. Immunopharmacology. 32:1996;82-84.