Effects of the opioid antagonist naltrexone on feeding induced by DAMGO in the ventral tegmental area and in the nucleus accumbens shell region in the rat

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 285, Issue 5 54-5, 2003, Pages

  MacDonald, Amy F ^a   Billington, Charles J ^b,c   Levine, Allen S ^a,b,c,d  

^a UNIVERSITY OF MINNESOTA   (United States)

^b University of Minnesota   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d VA MEDICAL CENTER   (United States)

Author keywords

Food intake; Mesolimbic; Microinjection; Reward

Indexed keywords

DOPAMINE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; NALTREXONE; OPIATE ANTAGONIST;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; DOSE RESPONSE; FEEDING; FOOD INTAKE; MALE; MESOLIMBIC DOPAMINERGIC SYSTEM; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; REWARD; VENTRAL TEGMENTUM;

EID: 0142084605     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00271.2003     Document Type: Article

References (32)

1. Bakshi VP and Kelley AE. Feeding induced by opioid stimulation of the ventral striatum: role of opiate receptor subtypes. J Pharmacol Exp Ther 265: 1253-1260, 1993.
2. Echo JA, Lamonte N, Ackerman TF, and Bodnar RJ. Alterations in food intake elicited by GABA and opioid agonists and antagonists administered into the ventral tegmental area region of rats. Physiol Behav 76: 107-116, 2002.
3. Echo JA, Lamonte N, Christian G, Znamensky V, Ackerman TF, and Bodnar RJ. Excitatory amino acid receptor subtype agonists induce feeding in the nucleus accumbens shell in rats: opioid antagonist actions and interactions with μ-opioid agonists. Brain Res 921: 86-97, 2001.
4. Giraudo SQ, Billington CJ, and Levine AS. Effects of the opioid antagonist naltrexone on feeding induced by DAMGO in the central nucleus of the amygdala and in the paraventricular nucleus in the rat. Brain Res 782: 18-23, 1998.
5. Giraudo SQ, Kotz CM, Billington CJ, and Levine AS. Association between the amygdala and nucleus of the solitary tract in μ-opioid induced feeding in the rat. Brain Res 802: 184-188, 1998.
6. Groenewegen HJ and Russchen FT. Organization of the efferent projections of the nucleus accumbens to pallidal, hypothalamic, and mesencephalic structures: a tracing and immunohistochemical study in the cat. J Comp Neurol 223: 347-367, 1984.
7. Kalivas PW, Duffy P, and Barrow J. Regulation of the mesocorticolimbic dopamine system by glutamic acid receptor subtypes. J Pharmacol Exp Ther 251: 378-387, 1989.
8. Kelley AE and Berridge KC. The neuroscience of natural rewards: relevance to addictive drugs. J Neurosci 22: 3306-3311, 2002.
9. Kirkham TC and Blundell JE. Dual action of naloxone on feeding revealed by behavioural analysis: separate effects on initiation and termination of eating. Appetite 5: 45-52, 1984.
10. Kirkham TC and Blundell JE. Effects of naloxone and naltrexone on meal patterns of freely-feeding rats. Pharmacol Biochem Behav 26: 515-520, 1987.
11. Kirkham TC and Cooper SJ. Attenuation of sham feeding by naloxone is stereospecific: evidence for opioid mediation of orosensory reward. Physiol Behav 43: 845-847, 1988.
12. Kirkham TC and Cooper SJ. Naloxone attenuation of sham feeding is modified by manipulation of sucrose concentration. Physiol Behav 44: 491-494, 1988.
13. Lamonte N, Ackerman TF, and Bodnar RJ. Opioid subtype antagonist modulation of μ opioid-induced feeding: ventral tegmental area and nucleus accumbens interactions in rats. Soc Neurosci Abstr 275.19: 2002.
14. Lamonte N, Echo JA, Ackerman TF, Christian G, and Bodnar RJ. Analysis of opioid receptor subtype antagonist effects upon μ opioid agonist-induced feeding elicited from the ventral tegmental area of rats. Brain Res 929: 96-100, 2002.
15. Levine AS and Billington CJ. Why do we eat? A neural systems approach. Annu Rev Nutr 17: 597-619, 1997.
16. Levine AS, Weldon DT, Grace M, Cleary JP, and Billington CJ. Naloxone blocks that portion of feeding driven by sweet taste in food-restricted rats. Am J Physiol Regul Integr Comp Physiol 268: R248-R252, 1995.
17. Majeed NH, Przewlocka B, Wedzony K, and Przewlocki R. Stimulation of food intake following opioid microinjection into the nucleus accumbens septi in rats. Peptides 7: 711-716, 1986.
18. Noel MB and Wise RA. Ventral tegmental injections of a selective μ- or δ-opioid enhance feeding in food-deprived rats. Brain Res 673: 304-312, 1995.
19. Paxinos G. The Rat Nervous System. San Diego, CA: Academic, 1995.
20. Paxinos G and Watson C. The Rat Brain in Stereotaxic Coordinates. San Diego, CA: Academic, 1997.
21. Pecina S and Berridge KC. Opioid site in nucleus accumbens shell mediates eating and hedonic "liking" for food: map based on microinjection Fos plumes. Brain Res 863: 71-86, 2000.
22. Ragnauth A, Moroz M, and Bodnar RJ. Multiple opioid receptors mediate feeding elicited by μ and δ opioid receptor subtype agonists in the nucleus accumbens shell in rats. Brain Res 876: 76-87, 2000.
23. Ragnauth A, Znamensky V, Moroz M, and Bodnar RJ. Analysis of dopamine receptor antagonism upon feeding elicited by μ and δ opioid agonists in the shell region of the nucleus accumbens. Brain Res 877: 65-72, 2000.
24. Spanagel R, Herz A, and Shippenberg TS. Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proc Natl Acad Sci USA 89: 2046-2050, 1992.
25. Swanson LW. The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat. Brain Res Bull 9: 321-353, 1982.
26. Taber MT, Zernig G, and Fibiger HC. Opioid receptor modulation of feeding-evoked dopamine release in the rat nucleus accumbens. Brain Res 785: 24-30, 1998.
27. Tanda G and Di Chiara G. A dopamine-μ1 opioid link in the rat ventral tegmentum shared by palatable food (Fonzies) and non-psychostimulant drugs of abuse. Eur J Neurosci 10: 1179-1187, 1998.
28. Walaas I and Fonnum F. Biochemical evidence for γ-aminobutyrate containing fibres from the nucleus accumbens to the substantia nigra and ventral tegmental area in the rat. Neuroscience 5: 63-72, 1980.
29. Weldon DT, O'Hare E, Cleary J, Billington CJ, and Levine AS. Effect of naloxone on intake of cornstarch, sucrose, and polycose diets in restricted and nonrestricted rats. Am J Physiol Regul Integr Comp Physiol 270: R1183-R1188, 1996.
30. Xi ZX and Stein EA. GABAergic mechanisms of opiate reinforcement. Alcohol Alcohol 37: 485-494, 2002.
31. Zhang M and Kelley AE. Enhanced intake of high-fat food following striatal μ-opioid stimulation: microinjection mapping and fos expression. Neuroscience 99: 267-277, 2000.
32. Znamensky V, Echo JA, Lamonte N, Christian G, Ragnauth A, and Bodnar RJ. γ-Aminobutyric acid receptor subtype antagonists differentially alter opioid-induced feeding in the shell region of the nucleus accumbens in rats. Brain Res 906: 84-91, 2001.