Spinal upregulation of the nitric oxide synthase-interacting protein NOSIP in a rat model of inflammatory pain

Neuroscience Letters

Volumn 350, Issue 1, 2003, Pages 13-16

  Dreyer, Jacqueline ^a   Hirlinger, David ^a   Müller Esterl, Werner ^b   Oess, Stefanie ^b   Kuner, Rohini ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Complete Freund's adjuvant; Endothelial nitric oxide synthase; Inflammatory pain; Neuronal nitric oxide synthase; Nitric oxide synthase interacting protein

Indexed keywords

FREUND ADJUVANT; NITRIC OXIDE SYNTHASE INTERACTING PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ASSAY; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; MALE; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD NERVE CELL; UPREGULATION;

EID: 0142075286     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(03)00771-7     Document Type: Article

References (17)

1. Alderton W.K., Cooper C.E., Knowles R.G. Nitric oxide synthases: structure, function and inhibition. Biochem. J. 357:2001;593-615.
2. Dedio J., König P., Wohlfart P., Schroeder C., Kummer W., Müller-Esterl W. NOSIP, a novel modulator of endothelial nitric oxide synthase activity. FASEB J. 15:2001;79-89.
3. Granados-Soto V., Rufino M.O., Gomes Lopes L.D., Ferreira S.H. Evidence for the involvement of the nitric oxide-cGMP pathway in the antinociception of morphine in the formalin test. Eur. J. Pharmacol. 340:1997;177-180.
4. Guhring H., Gorig M., Ates M., Coste O., Zeilhofer H.U., Pahl A., Rehse K., Brune K. Suppressed injury-induced rise in spinal prostaglandin E2 production and reduced early thermal hyperalgesia in iNOS-deficient mice. J. Neurosci. 20:2000;6714-6720.
5. Henrich M., Hoffman K., König P., Gruß M., Fischbach T., Gödecke A., Hempelmann G., Kummer W. Sensory neurons respond to hypoxia with NO production associated with mitochondria. Mol. Cell. Neurosci. 20:2002;307-322.
6. Hunt S.P., Mantyh P.W., Priestley J.V. The organization of biochemically characterized sensory neurons. Scott S.A. Sensory Neurons: Diversity, Development and Plasticity. 1992;60-76 Oxford University Press, New York.
7. Kolhekar R., Meller S.T., Gebhart G.F. Characterization of the role of spinal NMDA receptors in thermal nociception in the rat. Neuroscience. 57:1993;385-395.
8. Kolhekar R., Murphy S., Gebhart G.F. Thalamic NMDA receptors modulate inflammation-produced hyperalgesia in the rat. Pain. 71:1997;31-40.
9. Kuner R., Swiercz J.M., Zywietz A., Tappe A., Offermanns S. Characterization of the expression of PDZ-RhoGEF, LARG and Galpha12/ Galpha13proteins in the murine nervous system. Eur. J. Neurosci. 16:2002;2333-2341.
10. Levy D., Tal M., Hoke A., Zochodne D.W. Transient action of the endothelial constitutive nitric oxide synthase (ecNOS) mediates the development of thermal hypersensitivity following peripheral nerve injury. Eur. J. Neurosci. 12:2000;2323-2332.
11. Maihöfner C., Euchenhofer C., Tegeder I., Beck K.F., Pfeilschifter J., Geisslinger G. Regulation and immunohistochemical localization of nitric oxide synthases and soluble guanylyl cyclase in mouse spinal cord following nociceptive stimulation. Neurosci. Lett. 290:2000;71-75.
12. Maihöfner C., Tegeder I., Euchenhofer C., Dewitt D., Brune K., Bang R., Neuhuber W., Geisslinger G. Localization and regulation of cyclo-oxygenase-1 and -2 and neuronal nitric oxide synthase in mouse spinal cord. Neuroscience. 101:2000;1093-1108.
13. Meller S.T., Cummings C.P., Traub R.J., Gebhart G.F. The role of nitric oxide in the development and maintenance of hyperalgesia produced by intraplantar injection of carrageenan in the rat. Neuroscience. 60:1994;36774.
14. Meller S.T., Gebhart G.F. Nitric oxide (NO) and nociceptive processing in the spinal cord. Pain. 52:1993;127-136.
15. Molander C., Xu Q., Grant G. The cytoarchitectonic organization of the spinal cord in the rat. I. The lower thoracic and lumbosacral cord. J. Comp. Neurol. 230:1984;133-141.
16. Sousa A.M., Prado W.A. The dual effect of a nitric oxide donor in nociception. Brain Res. 897:2001;9-19.
17. Zimmermann K., Opitz N., Dedio J., Renne C., Müller-Esterl W., Oess S. NOSTRIN: a protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase. Proc. Natl. Acad. Sci. USA. 99:2002;17167-17172.