Effects of ethanol on cocaine discrimination in rats

Pharmacology Biochemistry and Behavior

Volumn 75, Issue 4, 2003, Pages 837-844

  Gatch, Michael B ^a   Youngblood, Bradley D ^a   Forster, Michael J ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Cocaine; Drug discrimination; Ethanol; GABAA receptor; Rat

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; ALCOHOL; COCAINE; DIAZEPAM; PENTETRAZOLE; PENTOBARBITAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCAINE DEPENDENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISCRIMINATION LEARNING; DISCRIMINATIVE STIMULUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0142074887     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(03)00158-8     Document Type: Article

References (36)

1. Barrett A.C., Morgan D., Izenwasser S., Picker M.J. Cocaine-like discriminative stimulus effects and [3H]dopamine uptake inhibition produced by selected partial opioid agonists. Behav. Pharmacol. 12:2001;225-235.
2. Callahan P.M., Cunningham K.A. Discriminative stimulus properties of cocaine in relation to dopamine D2 receptor function in rats. J. Pharmacol. Exp. Ther. 266:1993;585-592.
3. Colpaert F.C., Koek W. Empirical evidence that the state dependence and drug discrimination paradigms can generate different outcomes. Psychopharmacology. 120:1995;272-279.
4. Cunningham K.A., Appel J.B. Discriminative stimulus properties of cocaine and phencyclidine similarities in the mechanism of action. Colpaert F.C., Slangen J.L. Drug discrimination: applications in CNS pharmacology. 1982;181-192 Elsevier, Amsterdam.
5. Emmett-Oglesby M.W., Wurst M., Lal H. Discriminative stimulus properties of a small dose of cocaine. Neuropharmacology. 22:1983;97-101.
6. Emmett-Oglesby M.W., Shippenberg T.S., Herz A. Tolerance and cross-tolerance to the discriminative stimulus properties of fentanyl and morphine. J. Pharmacol. Exp. Ther. 245:1988;17-23.
7. Gauvin D.V., Young A.M. Perceptual masking of drug stimuli. Drug Dev. Res. 16:1989;151-162.
8. Grant K.A., Knisely J.S., Tabakoff B., Barrett J.E., Balster R.L. Ethanol-like discriminative stimulus effects of non-competitive N-methyl-D-aspartate antagonists. Behav. Pharmacol. 2:1991;87-95.
9. Harris C.M., Emmett-Oglesby M.W., Lal H. Sensitivity of pentylenetetrazol discrimination increased by a stimulus fading technique. Psychopharmacology. 98:1989;460-464.
10. Hedaya M.A., Pan W.J. Cocaine and alcohol interactions in naive and alcohol-pretreated rats. Drug Metab. Dispos. 24:1996;807-812.
11. Hedaya M.A., Pan W.J. Effect of alcohol coadministration on the plasma and brain concentrations of cocaine in rats. Drug Metab. Dispos. 25:1997;647-650.
12. Institute of Laboratory Animal Resources Guide for the care and use of laboratory animals. 1986;National Academy Press, Washington (DC).
13. Jung M.E., McNulty M.A., Goeders N.E. Cocaine increases benzodiazepine receptors labeled in the mouse brain in vivo with [3H]Ro 15-1788. NIDA Res. Monogr. 95:1989;512-513.
14. Kleven M.S., Kamenka J.-M., Vignon J., Koek W. Pharmacological characterization of the discriminative stimulus properties of the phencyclidine analog N-[1-(2-benzo(b)thiophenyl)-cyclohexyl]piperidine. Psychopharmacology. 145:1999;370-377.
15. Koek W., Colpaert F.C., Woods J.H., Kamenka J.-M. The phencyclidine (PCP) analog N-(1-(2-benzo(B)thiophenyl) cyclohexyl) piperidine shares cocaine-like but not other characteristic behavioral effects with PCP, ketamine and MK-801. J. Pharmacol. Exp. Ther. 250:1989;1019-1027.
16. Koek W., Kleven M.S., Colpaert F.C. Effects of the NMDA antagonist, dizocilpine, in various drug discriminations: characterization of intermediate levels of drug lever selection. Behav. Pharmacol. 6:1995;590-600.
17. Koob G.F., Nestler E.J. The neurobiology of drug addiction. J. Neuropsychiatry Clin. Neurosci. 9:1997;482-497.
18. Lane J.D., Pickering C.L., Hooper M.L., Fagan K., Tyers M.B., Emmett-Oglesby M.W. Failure of ondansetron to block the discriminative or reinforcing stimulus effects of cocaine in the rat. Drug Alcohol Depend. 30:1992;151-162.
19. McCance-Katz E.F., Price L.H., McDougle C.J., Kosten T.R., Black J.E., Jatlow P.I. Concurrent cocaine-ethanol ingestion in humans: pharmacology, physiology, behavior, and the role of cocaethylene. Psychopharmacology. 111:1993;39-46.
20. Mhatre M.C., Carl K., Garrett K.M., Holloway F.A. Opiate delta-2-receptor antagonist naltriben does not alter discriminative stimulus effects of ethanol. Pharmacol. Biochem. Behav. 66:2000;701-706.
21. Munzar P., Kutkat S.W., Miller C.R., Goldberg S.R. Failure of baclofen to modulate discriminative-stimulus effects of cocaine or methamphetamine in rats. Eur. J. Pharmacol. 169:2000;174.
22. Negus S.S., Mello N.K., Fivel P.A. Effects of GABA agonists and GABA-A receptor modulators on cocaine discrimination in rhesus monkeys. Psychopharmacology. 152:2000;398-407.
23. Overton D.A. Test for a neurochemically specific mechanism mediating drug discriminations and for stimulus masking. Psychopharmacology. 81:1983;340-344.
24. Pan W.J., Hedaya M.A. Cocaine and alcohol interactions in the rat: effect of cocaine and alcohol pretreatments on cocaine pharmacokinetics and pharmacodynamics. J. Pharm. Sci. 88:1999;1266-1274.
25. Peltier R.L., Emmett-Oglesby M.W., Thomas W.H., Schenk S. Failure of ritanserin to block the discriminative or reinforcing stimulus effects of cocaine. Pharmacol. Biochem. Behav. 48:1994;473-478.
26. Peltier R.L., Li D.H., Lytle D., Taylor C.M., Emmett-Oglesby M.W. Chronic D-amphetamine or methamphetamine produces cross-tolerance to the discriminative and reinforcing stimulus effects of cocaine. J. Pharmacol. Exp. Ther. 277:1996;212-218.
27. Prather P.L., Lal H. Protracted withdrawal: sensitization of the anxiogenic response to cocaine in rats concurrently treated with ethanol. Neuropsychopharmacology. 6:1992;23-29.
28. Schechter M.D. Discriminative effects of cocaethylene in rats trained to discriminate cocaine or ethanol. Life Sci. 55:1994;1033-1043.
29. Schechter M.D. Cocaethylene produces discriminative stimulus properties in the rat: effect of cocaine and ethanol coadministration. Pharmacol. Biochem. Behav. 51:1995;285-298.
30. Schechter M.D. Discrimination of cocaethylene in rats trained to discriminate between its components. Eur. J. Pharmacol. 320:1997;1-7.
31. Schuster C.R., Johanson C.-E. Efficacy, dependence potential and neurotoxicity of anorectic drugs. Seiden L.S., Balster R.L. Behavioral pharmacology: the current status. 1985;263-279 Alan R. Liss, New York.
32. Shearman G.T., Lal H. Discriminative stimulus properties of pentylenetetrazol and bemegride: some generalization and antagonism tests. Psychopharmacology. 64:1979;315-319.
33. Shearman G.T., Lal H. Discriminative stimulus properties of cocaine related to an anxiogenic action. Prog. Neuropsychopharmacol. Biol. Psychiatry. 5:1981;57-63.
34. Substance Abuse and Mental Health Services Administration. Summary of findings from the 2000 national household survey on drug abuse. Rockville (MD): Office of Applied Studies, NHSDA Series H-13, DHHS Publication No. (SMA) 01-3549; 2001.
35. Ye J.H., Liu P.L., Wu W.H., McArdle J.J. Cocaine depresses GABAA current of hippocampal neurons. Brain Res. 770:1997;169-175.
36. Ye J.H., Ren J., Krnjevic K., Liu P.L., McArdle J.J. Cocaine and lidocaine have additive inhibitory effects on the GABAA current of acutely dissociated hippocampal pyramidal neurons. Brain Res. 821:1999;26-32.