Treatment of Alcohol Abuse: An Evidence-Based Review

Alcoholism: Clinical and Experimental Research

Volumn 27, Issue 10, 2003, Pages 1645-1656

  Berglund, Mats ^a   Thelander, Sten ^b   Salaspuro, Mikko ^e   Franck, Johan ^c   Andréasson, Sven ^d   Öjehagen, Agneta ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b Swedish Council on Technology Assessment in Health Care   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d STAD   (Sweden)

^e University Hospital ^*

Author keywords

Alcohol; Alcohol Dependence; Alcohol Withdrawal; Prevention; Treatment

Indexed keywords

4 AMINOBUTYRIC ACID; ACAMPROSATE; ALCOHOL; ANTIDEPRESSANT AGENT; BARBITURIC ACID DERIVATIVE; BENACTYZINE; BENZODIAZEPINE DERIVATIVE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BUSPIRONE; CALCIUM ANTAGONIST; CARBAMAZEPINE; CLOMETHIAZOLE; CLONIDINE; DISULFIRAM; DOPAMINE RECEPTOR STIMULATING AGENT; ENALAPRIL; HYDANTOIN DERIVATIVE; LITHIUM; NALMEFENE; NALTREXONE; NEUROLEPTIC AGENT; NITROUS OXIDE; PARALDEHYDE; PAROXETINE; PLACEBO; PROPOFOL; PYRIDOXINE; SEROTONIN AGONIST; SEROTONIN UPTAKE INHIBITOR; THIAMINE;

ALCOHOL WITHDRAWAL; ALCOHOLISM; ANXIETY DISORDER; BEHAVIOR THERAPY; CLINICAL TRIAL; COGNITIVE THERAPY; CONFERENCE PAPER; DELIRIUM TREMENS; DEPRESSION; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; EVIDENCE BASED MEDICINE; FAMILY THERAPY; HOMELESSNESS; HOSPITAL PATIENT; HUMAN; MARITAL THERAPY; MENTAL DISEASE; OUTPATIENT; PATIENT COUNSELING; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; PSYCHOSOCIAL CARE; SECONDARY PREVENTION; SOCIAL PHOBIA;

ALCOHOLISM; EVIDENCE-BASED MEDICINE; HUMANS; SOCIETIES, MEDICAL; SWEDEN;

EID: 0142061074     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ALC.0000090144.99832.19     Document Type: Conference Paper

References (104)

1. Adams A, Ockene JK, Wheeler EV, Hurley TG (1998) Alcohol counselling. Physicians will do it. Gen Intern Med 13:692-698.
2. Alden LE (1988) Behavior self-management controlled-drinking strategies in a context of secondary prevention. J Consult Clin Psychol 56:280-286.
3. Altamura AC, Mauri MC, Giradi T, Panetta B (1990) Alcoholism and depression: a placebo controlled study with viloxazine. Int J Clin Pharmacol Res 10:293-298.
4. Anton RF, Moak DH, Waid LR, Latham PK, Malcolm RJ, Dias JK (1999) Naltrexone and cognitive behavioral therapy for the treatment of outpatient alcoholics: results of a placebo-controlled trial. Am J Psychiatry 156:1758-1764.
5. Arborelius E, Damström-Thakker K, Krakau I, Rydberg U (1997) Dilemmas in implementing alcohol-related secondary prevention in primary care using a behavioural method. Eur Addict Res 3:150-157.
6. Athen D, Hippius H, Meyendorf R, Riemer C, Steiner C (1977) [Comparison of the effectiveness of neuroleptics and chlormethiazol in the treatment of alcoholic delirium]. Nervenarzt 48:528-532.
7. Balldin J, Berglund M, Borg S, Månsson M, Bendtsen P, Franck J, Gustafsson L, Halldin J, Nilsson L-H, Stolt G, Willander A (2003) A 6-month controlled naltrexone study: combined effect with cognitive behavioral therapy in outpatient treatment of alcohol dependence. Alcohol Clin Exp Res 27:1142-1149.
8. Barber JG, Crisp BR (1995) The "pressures to change" approach to working with the partners of heavy drinkers. Addiction 90:269-276.
9. Barrias JA, Chabac S, Ferreira L, Fonte A, Potgieter AS, Teixeira de Sousa E (1997) Acamprosate: multicenter Portuguese efficacy and tolerance evaluation study. Psyquiatria Clin 18:149-160.
10. Bennie C (1998) Comparison of home detoxification and minimal intervention strategies for problem drinkers. Alcohol Alcohol 33:157-163.
11. Benuzzi P, Muller C (1967) [3 methods of treating delirium tremens. Comparative study]. Schweiz Med Wochenschr 97:1283-1289.
12. Berglund M, Johnsson E, Thelander S eds (2003) Treatment of Alcohol and Drug Abuse. An Evidence-Based Review. Wiley-VCH, Weinheim, United Kingdom.
13. Besson J, Aeby F, Kasas A, Lehert P, Potgieter A (1998) Combined efficacy of acamprosate and disulfiram in the treatment of alcoholism: a controlled study. Alcohol Clin Exp Res 22:573-579.
14. Borenstein M, Rothstein H (1999) Comprehensive Meta-Analysis. A Computer Program for Systematic Reviews. Biostat, Englewood, NJ.
15. Brown R (1980) Conventional education and controlled-drinking education courses with convicted drunken drivers. Behav Ther 11:632-642.
16. Bruno F (1989) Buspirone in the treatment of alcoholic patients. Psychopathology 22:49-59.
17. Cadogan DA (1973) Marital group therapy in the treatment of alcoholism. Q J Alcohol 34:1187-1194.
18. Calanca A, Jalonetsky S, Muller C (1977) Evaluation of treatment with hemineurine in delirium tremens. Encephale 3:63-69.
19. Chapman PLH, Huygens I (1988) Evaluation of three treatment programmes for alcoholism: an experimental study with 6- and 18-month follow-ups. Br J Addict 83:67-81.
20. Chick J, Anton R, Checinski K, Croop R, Drummond C, Farmer R, Labriola D, Marshall J, Moncrieff J, Morgan MY, Peters T, Ritson B (2000a) A multicenter, randomized, double-blind, placebo-controlled trial of naltrexone in the treatment of alcohol dependence or abuse. Alcohol Alcohol 35:587-593.
21. Chick J, Howlett H, Morgan MY, Ritson B (2000b) United Kingdom Multicentre Acamprosate Study (UKMAS): a 6 month prospective study of acamprosate versus placebo in preventing relapse after withdrawal from alcohol. Alcohol Alcohol 35:176-187.
22. Chick J, Ritson B, Connaughton J, Stewart A, Chick J (1988) Advice versus extended treatment for alcoholism: a controlled study. Br J Addict 83:159-170.
23. Cook CC, Hallwood PM, Thomson AD (1998) B vitamin deficiency and neuropsychiatric syndromes in alcohol misuse. Alcohol Alcohol 33:317-336.
24. Coomes TR, Smith SW (1997) Successful use of propofol in refractory delirium tremens. Ann Emerg Med 30:825-828.
25. Cornelius JR, Salloum IM, Ehler JG, Jarrett PJ, Cornelius MD, Perel JM, Thase ME, Black A (1997) Fluoxetine in depressed alcoholics. A double-blind, placebo-controlled trial. Arch Gen Psychiatry 54:700-705.
26. Cushman WC, Cutler JA, Hanna E, Bingham SF, Follman D, Harford T, Dubbert P, Allender S, Dufour M, Collins JF, Walsh SM, Kirk GF, Burg M, Felicetta JV, Hamilton BP, Katz LA, Perry M Jr, Willenbring LM, Lakshman R, Hamburger RJ (1998) Prevention and treatment of hypertension study (PATHS): effects of an alcohol treatment program on blood pressure. Arch Intern Med 158:1197-1207.
27. Edwards G, Orford J, Egert S, Guthrie S, Hawker A, Hensman C, Mitcheson M, Oppenheimer E, Taylor C (1977) Alcoholism: a controlled trial of "treatment" and "advice." J Stud Alcohol 38:1004-1031.
28. Edwards GK, Rollnick S (1997) Outcome studies of brief alcohol intervention in general practice: the problem of lost subjects. Addiction 92:1699-1704.
29. Elvy GA, Wells JE, Baird KA (1988) Attempted referral as intervention for problem drinking in the general hospital. Br J Addict 83:83-89.
30. Erwin WE, Williams DG, Speir WA (1998) Delirium tremens. South Med J 91:425-432.
31. Ewing JA (1960) The first phase of alcoholic rehabilitation: report on a controlled study. Q J Stud Alcohol 21:68-81.
32. Fleming MF, Barry KL, Manwell LB, Johnson K, London R (1997) Brief physician advice for problem drinkers. A randomised controlled trial in community-based primary care practices. JAMA 277:1039-1045.
33. Gagiano CA (1994) Nitrous oxide for alcohol withdrawal and other psychiatric disorders. S Afr Med J 84:359.
34. Gastpar M, Bonnet U, Böning J, Mann K, Schmidt LG, Soyka M, Wetterling T, Kielstein V, Labriola D, Croop R (2002) Lack of efficacy of naltrexone in the prevention of alcohol relapse: results from a German multicenter study. J Clin Psychopharmacol 22:592-598.
35. Gentiello LM, Rivara FP, Donovan DM, Jurkovich GJ, Daranciang E, Dunn CW, Villaveces A, Copass M, Ries RR (1999) Alcohol interventions in a trauma center as a means of reducing the risk of injury recurrence. Ann Surg 230:473-484.
36. Geerlings PJ, Ansoms C, Van den Brink W (1997) Acamprosate and prevention of relapse in alcoholics. Results of a randomized, placebo-controlled, double-blind study in out-patient alcoholics in the Netherlands, Belgium and Luxembourg. Eur Addict Res 3:129-137.
37. Golbert TM, Sanz CJ, Rose HD, Leitschuh TH (1967) Comparative evaluation of treatment of alcohol withdrawal syndromes. JAMA 201: 99-102.
38. Goldberg HI, Mullen M, Ries RK, Psaty BM, Ruch BP (1991) Alcohol counselling in a general medicine clinic. A randomised controlled trial of strategies to improve referral and show rates. Med Care (7 Suppl) 29:JS49-JS56.
39. Gual A, Lehert P (2001) Acamprosate during and after acute alcohol withdrawal: a double-blind placebo-controlled study in Spain. Alcohol Alcohol 36:413-418.
40. Harris KB, Miller WR (1990) Behavioral self-control training for problem drinkers: components of efficacy. Psychol Addict Behav 4:82-90.
41. Heather N, Campion PD, Neville RG, Maccabe D (1987) Evaluation of a controlled drinking minimal intervention for problem drinkers in general practice (the DRAMS scheme). J R Coll Gen Pract 37:358-363.
42. Heinälä P, Alho H, Kiianmaa, K, Lönnqvist J, Kuoppasalmi K, Sinclair JD (2001) Targeted use of naltrexone without prior detoxification in the treatment of alcohol dependence: a factorial double-blind placebo controlled trial. J Clin Psychopharmacol 21:2987-2992.
43. Holbrook AM, Crowther R, Lotter A, Cheng C, King D (1999) Diagnosis and management of acute alcohol withdrawal. CMAJ 160:675-680.
44. Holder HD, Cisler RA, Longabaugh R, Stout RL, Treno AJ, Zweben A (2000) Alcohol treatment and medical care costs from Project MATCH. Addiction 95:999-1013.
45. Institute of Medicine (1990) Broadening the Base of Treatment for Alcohol Problems. National Academy Press, Washington, DC.
46. Kaim SC, Klett CJ, Rothfeld B (1969) Treatment of the acute alcohol withdrawal state: a comparison of four drugs. Am J Psychiatry 125: 1640-1646.
47. Kelly AB, Halford WK, Young RM (2000) Maritally distressed women with alcohol problems: the impact of a short-term alcohol-focused intervention on drinking behaviour and marital satisfaction. Addiction 95:1537-1549.
48. Kivlahan DR, Marlatt GA, Fromme K, Coppel DB, Williams E (1990) Secondary prevention with college drinkers: evaluation of an alcohol skills training program. J Consult Clin Psychol 58:805-810.
49. Kranzler HR, Burleson JA, Del Boca FK, Babor TF, Korner P, Brown J, Bohn MJ (1994) Buspirone treatment of anxious alcoholics. A placebo-controlled trial. Arch Gen Psychiatry 51:391-397.
50. Kranzler HR, Modesto-Lowe V, Van Kirk J (2000) Naltrexone vs. nefazodone for treatment of alcohol dependence. A placebo-controlled trial. Neuropsychopharmacology 22:493-503.
51. Kranzler HR, Van Kirk J (2001) Efficacy of naltrexone and acamprosate for alcoholism treatment: a meta-analysis. Alcohol Clin Exp Res 25: 1335-1341.
52. Kristenson H, Österling A, Nilsson J-Å, Lindgärde F (2002) Prevention of alcohol-related deaths in middle-aged heavy drinkers. Alcohol Clin Exp Res 26:478-484.
53. Krystal JH, Cramer JA, Krol WF, Kirk GF, Rosenheck RA (2001) Naltrexone in the treatment of alcohol dependence. N Engl J Med 345: 1734-1739.
54. Ladewig D, Knecht T, Leher P, Fendl A (1993) Acamprosate - a stabilizing factor in long-term withdrawal of alcoholic patients [in German]. Ther Umsch 50:182-188.
55. Lappin R (1998) Propofol in delirium tremens. Ann Emerg Med 32:271-272.
56. Latt NC, Jurd S, Houseman J, Wutzke SE (2002) Naltrexone in alcohol dependence: a randomized controlled trial of effectiveness in a standard clinical setting. Med J Aust 176:530-534.
57. Lhuitre JP, Daoust M, Moore ND, Chretien P, Saligaut C, Tran G, Biosmare F, Hillemand B (1985) Ability of calcium bis acetyl homotaurine, a GABA agonist, to prevent relapse in weaned alcoholics. Lancet 1:1014-1016.
58. Malcolm R, Anton RF, Randall CL, Johnston A, Brady K, Thevos A (1992) A placebo-controlled trial of buspirone in anxious inpatient alcoholics. Alcohol Clin Exp Res 16:1007-1013.
59. Malcolm R, Myrick H, Roberts J, Wang W, Anton RF, Ballenger JC (2002) The effects of carbamazepine and lorazepam on single versus multiple previous alcohol withdrawals in an outpatient randomized trial. J Gen Intern Med 17:349-355.
60. Mason BJ, Kocsis JH, Ritvo EC, Cutler RB (1996) A double-blind placebo-controlled trial of desipramine in primary alcoholics stratified on the presence or absence of major depression. JAMA 275:1-7.
61. Mason BJ, Salvato FR, Williams LD, Ritvo EC, Cutler RB (1999) A double-blind, placebo-controlled study of oral nalmefene for alcohol dependence. Arch Gen Psychiatry 56:719-724.
62. Mayo-Smith MF (1997) Pharmacological management of alcohol withdrawal - a meta-analysis and evidence-based practice guideline. JAMA 278:144-151.
63. McGrath PJ, Nunes EV, Stewart JW, Goldman D, Agosti V, Ocepek-Welikson K, Quitkin FM (1996) Imipramine treatment of alcoholics with primary depression: a placebo-controlled clinical trial. Arch Gen Psychiatry 53:232-240.
64. Miller WR, Benefield RG, Tonigan JS (1993) Enhancing motivation for change in problem drinking: a controlled comparison of two therapist styles. J Consult Clin Psychol 61:455-461.
65. Monterosso JR, Flannery BA, Pettinati HM, Oslin DW, Rukstalis M, O'Brien CP, Volpicelli JR (2001) Predicting treatment response to naltrexone: the influence of craving and family history. Am J Addict 10:258-268.
66. Monti PM, Rohsenow, DJ, Swift RM, Gulliver SB, Colby SM, Mueller TI, Brown RA, Gordon A, Abrams DB, Niaura RS, Asher MK (2001) Naltrexone and cue exposure with coping and communication skills training for alcoholics: treatment process and 1-year outcomes. Alcohol Clin Exp Res 25:1634-1647.
67. Morris PLP, Hopwood M, Whelan G, Gardiner J, Drummond E (2001) Naltrexone for alcohol dependence: a randomized controlled trial. Addict 96:1565-1573.
68. Moskowitz G, Chalmers TC, Sacks HS, Fagerstrom RM, Smith H Jr (1983) Deficiencies of clinical trials of alcohol withdrawal. Alcohol Clin Exp Res 7:42-46.
69. Naranjo CA, Sellers EM, Chater K, Iversen P, Roach C, Sykora K (1983) Nonpharmacologic intervention in acute alcohol withdrawal. Clin Pharmacol Ther 34:214-219.
70. Nunes EV, McGrath PJ, Quitkin FM, Stewart JP, Harrison W, Tricamo E, Ocepek-Welikson K (1993) Imipramine treatment of alcoholism with comorbid depression. Am J Psychiatry 150:963-965.
71. Ochene JK, Abigail A, Hurley TC, Wheeler EV, Hebert JR (1999) Brief physician- and nurse practitioner-delivered counselling for high-risk drinkers. Arch Intern Med 159:2198-2205.
72. O'Malley SS, Jaffe A, Chang G, Witte G, Schottenfeld RS, Rounsaville B (1992) Naltrexone and coping skills therapy for alcohol dependence. A controlled study. Arch Gen Psychiatry 49:881-887.
73. Paille FM, Guelfi JD, Perkins AC, Royer RH, Steru L, Parot P (1995) Double-blind randomized multicentre trial of acamprosate in maintaining abstinence from alcohol. Alcohol Alcohol 30:239-247.
74. Pelc I, LeBon O, Verbanck P, Lehert PH, Opsomer L (1992) Calcium Acetyl Homotaurine for Maintaining Abstinence in Weaned Alcoholic Patients: A Placebo Controlled Double-Blind Multi-Centre Study, pp 348-352. Springer Verlag, New York.
75. Pelc I, Verbanck P, Le Bon O, Gavrilovic M, Lion K, Lehert P (1997) Efficacy and safety of acamprosate in the treatment of detoxified alcohol-dependent patients. A 90-day placebo-controlled dose-finding study. Br J Psychiatry 170:73-77.
76. Poldrugo F (1997) Acamprosate treatment in a long-term community-based alcohol rehabilitation programme. Addiction 92:1537-1546.
77. Powell BJ, Campbell JL, Landon JF, Liskow BI, Thomas HM, Nickel EJ, Dale TM, Penick EC, Samuelson SD, Lacoursiere RB (1995) A double-blind, placebo-controlled study of nortriptyline and bromocriptine in male alcoholics subtyped by comorbid psychiatric disorders. Alcohol Clin Exp Res 19:462-468.
78. Project MATCH Research Group (1997) Matching alcoholism treatments to client heterogeneity: Project MATCH posttreatment drinking outcomes. J Stud Alcohol 58:7-29.
79. Project MATCH Research Group (1998) Matching alcoholism treatments to client heterogeneity: Project MATCH three-year drinking outcomes. Alcohol Clin Exp Res 22:1300-1311.
80. Randall CL, Johnson MR, Thevos AK, Sonne SC, Thomas SE, Willard SL, Brady KT, Davidson JR (2001) Paroxetine for social anxiety and alcohol use in dual-diagnosed patients. Depress Anxiety 14:255-262.
81. Roy A (1998) Placebo-controlled study of sertraline in depressed recently abstinent alcoholics. Biol Psychiatry 44:633-637.
82. Roussaux JP, Hers D, Ferauge M (1996) Does acamprosate diminish the appetite for alcohol in weaned alcoholis? (French) J Pharm Belg 51: 65-68.
83. Rychtarik RG, Connors GJ, Whitney RB, McGillicuddy JM, Fitterling JM (2000) Treatment settings for persons with alcoholism: evidence for matching clients to inpatient versus outpatient care. J Clin Consult Psychol 68:277-289.
84. Sannibale C (1988) Differential effect of a set of brief interventions on the functioning of a group of "early-stage" problem drinkers. Aust Drug Alcohol Rev 7:147-155.
85. Sass H, Soyka M, Mann K, Ziegelgans-Berger W (1996) Relapse prevention by acamprosate. Results from a placebo-controlled study on alcohol dependence. Arch Gen Psychiatry 53:673-680.
86. SBU (1997) The Swedish Council on Technology Assessment in Health Care: Behandling med Neuroleptika (Treatment With Neuroleptics). SBU-repport No. 133/1, SBU, Stockholm.
87. Scott A, Anderson P (1990) Randomised controlled trial of general practitioner intervention in women with excessive alcohol consumption. Drug Alcohol Rev 10:313-321.
88. Sehnert W, Brecht HM, Nowak FG (1998) Hochdosierte i.v. clonidintherapi. Intensivmed Notfallsmed 4:270-280.
89. Sellers EM, Naranjo CA, Harrison M, Devenyi P, Sykora K (1983) Diazepam loading: simplified treatment of alcohol withdrawal. Clin Pharmacol Ther 34:822-826.
90. Sellman JD, Sullivan PF, Dore GM, Adamson SJ, MacEwan I (2001) A randomized controlled trial of motivational enhancement therapy (MET) for mild to moderate alcohol dependence. J Stud Alcohol 62:389-396.
91. Senft RA, Polen MR (1997) Brief intervention in a primary care setting for hazardous drinkers. Am J Prev Med 13:464-470.
92. Srisurapanont M, Jarusuraisin N (2002) Opioid antagonists for alcohol dependence (Cochrane Review), in The Cochrane Library, Issue 2. Update Software, Oxford.
93. Streeton C, Whelan G (2001) Naltrexone, a relapse prevention maintenance treatment of alcohol dependence: a meta-analysis of randomized controlled trials Alcohol Alcohol 36:544-552.
94. Suokas A (1992) Brief Intervention of Heavy Drinking in Primary Health Care: Hämeenlinna Study, Dissertation, University of Helsinki, Finland.
95. Tempesta E, Janiri L, Bignamini AB, Chabac S, Potgieter A (2000) Acamprosate and relapse prevention in the treatment of alcohol dependence: a placebo-controlled study. Alcohol Alcohol 35:202-209.
96. Tollefson GD, Lancaster SP, Montague-Clouse J (1991) The association of buspirone and its metabolite 1-pyrimidinylpiperazine in the remission of comorbid anxiety with depressive features and alcohol dependency. Psychopharmacol Bull 27:163-170.
97. Volpicelli JR, Alterman AI, Hayashida M, O'Brien CP (1992) Naltrexone in the treatment of alcohol dependence. Arch Gen Psychiatry 49:876-880.
98. Volpicelli JR, Rhines KC, Rhines JS, Volpicelli LA, Alterman AI, O'Brien CP (1997) Naltrexone and alcohol dependence: role of subject compliance. Arch Gen Psychiatry 54:737-742.
99. Wallace P, Cutler S, Haines A (1988) Randomised controlled trial of general practitioner intervention in patients with excessive alcohol consumption. BMJ 297:663-668.
100. Whitworth AB, Fischer F, Lesch OM, Nimmerrickter A, Oberbauer H, Platz T, Potgieter A, Walter H, Fleischhacker WW (1996) Comparison of acamprosate and placebo in long-term treatment of alcohol dependence. Lancet 347:1438-1442.
101. WHO Brief Intervention Study Group (1996) A cross-national trial of brief interventions with heavy drinkers. Am J Public Health 86:948-955.
102. Williams D, McBride AJ (1998) The drug treatment of alcohol withdrawal symptoms: a systematic review. Alcohol Alcohol 33:103-115.
103. Wutzke SE, Conigrave KM, Saunders JB, Hall WD (2002) The long-term effectiveness of brief interventions for unsafe alcohol consumption: a 10-year follow-up. Addiction 97:665-675.
104. Zweben A, Pearlman S, Li S (1988) A comparison of brief advice and conjoint therapy in the treatment of alcohol abuse: the results of the Marital Systems Study. Br J Addict 83:899-916.