A 6-month controlled naltrexone study: Combined effect with cognitive behavioral therapy in outpatient treatment of alcohol dependence

Alcoholism: Clinical and Experimental Research

Volumn 27, Issue 7, 2003, Pages 1142-1149

  Balldin, J ^a   Berglund, M ^b   Borg, S ^c   Månsson, Marianne ^b   Bendtsen, P ^d   Franck, J ^c   Gustafsson, L ^e   Halldin, J ^f   Nilsson, L H ^g   Stolt, G ^h   Willander, A ⁱ  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^e UMEÅ UNIVERSITY   (Sweden)

^f DANDERYD HOSPITAL   (Sweden)

^g CENTRAL HOSPITAL   (Sweden)

^h UPPSALA UNIVERSITY HOSPITAL   (Sweden)

ⁱ Previa Aura Clinic   (Sweden)

Author keywords

Alcohol Dependence; Cognitive Behavioral Therapy; Craving; Naltrexone

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; GAMMA GLUTAMYLTRANSFERASE; NALTREXONE; PLACEBO; TRANSFERRIN;

ADULT; ALCOHOL CONSUMPTION; ALCOHOLISM; AMBULATORY CARE; ANALYSIS OF VARIANCE; ARTICLE; BEHAVIOR THERAPY; CHI SQUARE DISTRIBUTION; CLINICAL TRIAL; COGNITIVE THERAPY; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRINKING BEHAVIOR; DRUG TOLERABILITY; ENZYME ACTIVITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; METHODOLOGY; OUTPATIENT CARE; PATIENT COMPLIANCE; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; TREATMENT OUTCOME; WITHDRAWAL SYNDROME;

ADULT; ALCOHOLISM; AMBULATORY CARE; ANALYSIS OF VARIANCE; BEHAVIOR THERAPY; CHI-SQUARE DISTRIBUTION; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; NALTREXONE;

EID: 10744229555     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ALC.0000075548.83053.A9     Document Type: Article

References (36)

1. Anton RF, Moak DH, Latham PK (1996) The obsessive compulsive drinking scale: a new method of assessing outcome in alcoholism treatment studies. Arch Gen Psychiatry 53:225-231.
2. Anton RF, Moak DH, Latham PK, Waid LR, Malcolm RJ, Dias JK, Roberts JS (2001) Posttreatment results of combining naltrexone with cognitive-behavior therapy for the treatment of alcoholism. J Clin Psychopharmacol 21:72-77.
3. Anton RF, Moak DH, Waid LR, Latham PK, Malcolm RJ, Dias JK (1999) Naltrexone and cognitive behavioral therapy for the treatment of outpatient alcoholics: results of a placebo-controlled trial. Am J Psychiatry 11:1758-1764.
4. Borg S, Helander A, Voltaire Carlsson A, Hogstrom Brandt AM (1995) Detection of relapses in alcohol-dependent patients using carbohydrate-deficient transferrin: improvement with individualized reference levels during long-term monitoring. Alcohol Clin Exp Res 19:961-963.
5. Chick J, Anton R, Checinski K, Croop R, Drummond DC, Farmer R, Labriola D, Marshall J, Moncrieff J, Morgan MY, Peters T, Ritson B (2000) A multicentre, randomized, double-blind, placebo-controlled trial of naltrexone in the treatment of alcohol dependence or abuse. Alcohol Alcohol 35:87-93.
6. Croop RS, Faulkner EB, Labriola DF (1997) The safety profile of naltrexone in the treatment of alcoholism. Results from a multicenter usage study. The Naltrexone Usage Study Group. Arch Gen Psychiatry 54:1130-1135.
7. Dahlgren L, Willander A (1989) Are special treatment facilities for female alcoholics needed? A controlled 2-year follow-up study from a specialized female unit (EWA) versus a mixed male/female treatment facility. Alcohol Clin Exp Res 13:499-504.
8. Derogatis L (1997) Administration, Scoring and Procedures Manual-1 for the Revised Version and Other Instruments of the Psychopathology Rating Scales Series. Johns Hopkins University School of Medicine, Baltimore.
9. Gastpar M, Bonnet U, Boning J, Mann K, Schmidt LG, Soyka M, Wetterling T, Kielstein V, Labriola D, Croop R (2002) Lack of efficacy of naltrexone in the prevention of alcohol relapse: results from a German multicenter study. J Clin Psychopharmacol 22:592-598.
10. Guardia J, Caso C, Arias F, Gual A, Sanahuja J, Ramirez M, Mengual I, Gonzalvo B, Segura L, Trujols J, Casas M (2002) A double-blind, placebo-controlled study of naltrexone in the treatment of alcohol-dependence disorder: results from a multicenter clinical trial. Alcohol Clin Exp Res 26:1381-1387.
11. Heinälä P, Alho H, Kuoppasalmi K, Sinclair D, Kiianmaa K, Lönnqvist J (1999) Targeted use of naltrexone without prior detoxification in the treatment of alcohol dependence: a factorial double-blind, placebo-controlled trial. J Clin Psychopharmacol 21:287-292.
12. Hersh D, Van Kirk JR, Kranzler HR (1998) Naltrexone treatment of comorbid alcohol and cocaine use disorders. Psychopharmacology (Berl) 139:44-52.
13. Kadden R, Carroll K, Donovan D, Cooney N, Monti P, Abrams D, Litt M, Hester R (1992) Cognitive-Behavioral Coping Skills Therapy Manual: A Clinical Research Guide for Therapists Treating Individuals With Alcohol Abuse and Dependence (NIAAA Monograph Series, Vol 3, NIH Publication No. 92-1895). US Government Printing Office, Washington, DC.
14. Kiefer F, Jahn H, Tarnaske T, Helwig H, Briken P, Holzbach R, Kämpf P, Stracke R, Baehr M, Naber D, Widemann K (2003) Comparing and combining naltrexone and acamprosate in relapse prevention of alcoholism. Arch Gen Psychiatry 60:92-99.
15. Kranzler HR, Modesto-Lowe V, Nuwayser ES (1998) Sustained-release naltrexone for alcoholism treatment: a preliminary study. Alcohol Clin Exp Res 22:1074-1079.
16. Kranzler HR, Modesto-Lowe V, Van Kirk J (2000) Naltrexone vs. nefazodone for treatment of alcohol dependence. A placebo-controlled trial. Neuropsychopharmacology 22:493-503.
17. Kranzler HR, Tennen H, Penta C, Bohn MJ (1997) Targeted naltrexone treatment of early problem drinkers. Addict Behav 22:431-436.
18. Krystal JH, Cramer JA, Krol WF, Kirk GF, Rosenheck RA (2001) Naltrexone in the treatment of alcohol dependence. N Engl J Med 345:1734-1739.
19. Latt NC, Jurd S, Houseman J, Wutzke SE (2002) Naltrexone in alcohol dependence: a randomised controlled trial of effectiveness in a standard clinical setting. Med J Aust 176:530-534.
20. McLellan AT, Luborsky L, Woody GE, O'Brien CP (1980) An improved diagnostic evaluation instrument for substance abuse patients. The Addiction Severity Index. J Nerv Ment Dis 168:26-33.
21. Modesto-Lowe V, Burleson JA, Hersh D, Bauer LO, Kranzler HR (1997) Effects of naltrexone on cue-elicited craving for alcohol and cocaine. Drug Alcohol Depend 49:9-16.
22. Monterosso JR, Flannery BA, Pettinati HM, Oslin DW, Rukstalis M, O'Brien CP, Volpicelli JR (2001) Predicting treatment response to naltrexone: the influence of craving and family history. Am J Addict 10:258-268.
23. Monti PM, Rohsenow DJ, Swift RM, Gulliver SB, Colby SM, Mueller TI, Brown RA, Gordon A, Abrams DB, Niaura RS, Asher MK (2001) Naltrexone and cue exposure with coping and communication skills training for alcoholics: treatment process and 1-year outcomes. Alcohol Clin Exp Res 25:1634-1647.
24. Morris PLP, Hopwood M, Whelan G, Gardiner J, Drummond J (2001) Naltrexone for alcohol dependence: a randomized controlled trial. Addiction 96:1565-1573.
25. Nordstrom G, Berglund M (1987) A prospective study of successful long-term adjustment in alcohol dependence: social drinking versus abstinence. J Stud Alcohol 48:95-103.
26. Öjehagen A, Skjaerris A, Berglund M (1988) Prediction of posttreatment drinking outcome in a 2-year out-patient alcoholic treatment program. A follow-up study. Alcohol Clin Exp Res 12:46-51.
27. O'Malley SS (1995) Naltrexone in the treatment of alcohol dependence: a combined analysis of two trials. Psychiatr Ann 25:681-688.
28. O'Malley SS, Jaffe AJ, Chang G, Rode S, Schottenfeld R, Meyer RE, Rounsaville B (1996) Six-month follow-up of naltrexone and psychotherapy for alcohol dependence. Arch Gen Psychiatry 53:217-224.
29. O'Malley SS, Jaffe AJ, Chang G, Schottenfeld RS, Meyer RE, Rounsaville B (1992) Naltrexone and coping skills therapy for alcohol dependence. A controlled study. Arch Gen Psychiatry 49:881-887.
30. Oslin D, Liberto JG, O'Brien J, Krois S, Norbeck J (1997) Naltrexone as an adjunctive treatment for older patients with alcohol dependence. Am J Geriatr Psychiatry 5:324-332.
31. Roberts JS, Anton RF, Latham PK, Moak DH (1999) Factor structure and predictive validity of the Obsessive Compulsive Drinking Scale. Alcohol Clin Exp Res 23:1484-1491.
32. Sobell LC, Sobell MB, Leo GI, Cancilla A (1988) Reliability of a timeline method: assessing normal drinkers' reports of recent drinking and a comparative evaluation across several populations. Br J Addict 83:393-402.
33. Stibler H (1991) Carbohydrate-deficient transferrin in serum. A new marker of potentially harmful alcohol consumption reviewed. Clin Chem 37:2029-2037.
34. Volpicelli JR, Alterman AI, Hayashida M, O'Brien CP (1992) Naltrexone in the treatment of alcohol dependence. Arch Gen Psychiatry 49:876-880.
35. Volpicelli JR, Rhines KC, Rhines JS, Volpicelli LA, Alterman AI, O'Brien CP (1997) Naltrexone and alcohol dependence. Role of subject compliance. Arch Gen Psychiatry 54:737-742.
36. Wetterling T, Veltrup C, Driessen M, John U (1999) Drinking pattern and alcohol-related medical disorders. Alcohol Alcohol 34:330-336.