SCOPUS 정보 검색 플랫폼

Volumn 1, Issue 12, 2003, Pages 2075-2083

Design, synthesis and evaluation of bifunctional inhibitors of type II dehydroquinase

(6) Toscano, Miguel D a Frederickson, Martyn a Evans, David P a Coggins, John R b Abell, Chris a González Bello, Concepción c

a UNIVERSITY OF CAMBRIDGE (United Kingdom)

b UNIVERSITY OF GLASGOW (United Kingdom)

c UNIVERSITY OF SANTIAGO DE COMPOSTELA (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOASSAY; CARBOXYLIC ACIDS; CRYSTAL STRUCTURE; CRYSTALLIZATION; CRYSTALLOGRAPHY; ENZYMES; MICROORGANISMS; MOLECULAR STRUCTURE; SYNTHESIS (CHEMICAL);

BIFUNCTIONAL INHIBITORS; DEHYDROQUINASE; QUINIC ACID; STREPTOMYCES CEOLICOLOR ENZYME;

ENZYME INHIBITION;

SALMONELLA; SALMONELLA TYPHI; STREPTOMYCES; STREPTOMYCES COELICOLOR;

3 DEHYDROQUINATE DEHYDRATASE; 3-DEHYDROQUINATE DEHYDRATASE; ENZYME INHIBITOR; HYDROLYASE; QUINIC ACID;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; ENZYMOLOGY; SALMONELLA TYPHI; STREPTOMYCES; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

BINDING SITES; DRUG DESIGN; ENZYME INHIBITORS; HYDRO-LYASES; MODELS, MOLECULAR; QUINIC ACID; SALMONELLA TYPHI; STREPTOMYCES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0142010043 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/b301731a Document Type: Article

Times cited : (20)

References (27)

1
- 0026575985
- C. Kleanthous, R. Deka, K. Davis, S.M. Kelly, A. Cooper, S. E. Harding, N. C. Price, A. R. Hawkins and J. R. Coggins, Biochem. J., 1992, 282, 687-695.
- (1992) Biochem. J. , vol.282 , pp. 687-695
- Kleanthous, C.¹ Deka, R.² Davis, K.³ Kelly, S.M.⁴ Cooper, A.⁵ Harding, S.E.⁶ Price, N.C.⁷ Hawkins, A.R.⁸ Coggins, J.R.⁹

2
- 0000439082
- C. Abell, in Enzymology and Molecular Biology of the Shikimate Pathway; Comprehensive Natural Products Chemistry, 1999, pp. 573-607.
- (1999) Enzymology and Molecular Biology of the Shikimate Pathway; Comprehensive Natural Products Chemistry , pp. 573-607
- Abell, C.¹

3
- 0018932939
- H. C. Steinrucken and N. Amhrein, Biochem. Biophys. Res. Commun., 1980, 94, 1207-1212.
- (1980) Biochem. Biophys. Res. Commun. , vol.94 , pp. 1207-1212
- Steinrucken, H.C.¹ Amhrein, N.²

4
- 0021829055
- N. H. Giles, M. E. Case, J. A. Baum, R. F. Geever, L. Huiet, V. B. Patel and B. M. Tyler, Microbiol. Rev., 1985, 49, 338-358.
- (1985) Microbiol. Rev. , vol.49 , pp. 338-358
- Giles, N.H.¹ Case, M.E.² Baum, J.A.³ Geever, R.F.⁴ Huiet, L.⁵ Patel, V.B.⁶ Tyler, B.M.⁷

5
- 0025770419
- (a) C. Kleanthous, M. Reilly, A. Cooper, S. Kelly, N. C. Price and J. R. Coggins, J. Biol. Chem., 1991, 266, 10893-10898
- (1991) J. Biol. Chem. , vol.266 , pp. 10893-10898
- Kleanthous, C.¹ Reilly, M.² Cooper, A.³ Kelly, S.⁴ Price, N.C.⁵ Coggins, J.R.⁶

6
- 0026592053
- (b) R. K. Deka, C. Kleanthous and J. R. Coggins, J. Biol. Chem., 1992, 267, 22237-22242
- (1992) J. Biol. Chem. , vol.267 , pp. 22237-22242
- Deka, R.K.¹ Kleanthous, C.² Coggins, J.R.³

7
- 0028845362
- (c) A. P. Leech, R. James, J. R. Coggins and C. Kleanthous, J. Biol. Chem., 1995, 270, 2587-25836.
- (1995) J. Biol. Chem. , vol.270 , pp. 25827-25836
- Leech, A.P.¹ James, R.² Coggins, J.R.³ Kleanthous, C.⁴

8
- 37049078899
- (a) J. Harris, C. Kleanthous, J. R. Coggins, A. R. Hawkins and C. Abell, J. Chem. Soc., Chem. Commun., 1993, 1080-1081
- (1993) J. Chem. Soc., Chem. Commun. , pp. 1080-1081
- Harris, J.¹ Kleanthous, C.² Coggins, J.R.³ Hawkins, A.R.⁴ Abell, C.⁵

9
- 0027237831
- (b) A. Shneier, J. Harris, C. Kleanthous, J. R. Coggins, A. R. Hawkins, and C. Abell, Bioorg. Med. Chem. Lett., 1993, 3, 1399-1402
- (1993) Bioorg. Med. Chem. Lett. , vol.3 , pp. 1399-1402
- Shneier, A.¹ Harris, J.² Kleanthous, C.³ Coggins, J.R.⁴ Hawkins, A.R.⁵ Abell, C.⁶

10
- 0029824788
- (c) J. M. Harris, C. Gonzalez-Bello, C. Kleanthous, A. R. Hawkins, J. R. Coggins and C. Abell, Biochem. J., 1996, 319, 333-336.
- (1996) Biochem. J. , vol.319 , pp. 333-336
- Harris, J.M.¹ Gonzalez-Bello, C.² Kleanthous, C.³ Hawkins, A.R.⁴ Coggins, J.R.⁵ Abell, C.⁶

11
- 0013262319
- J. M. Harris, C. González-Bello, M. K. Manthey, J. R. Coggins and C. Abell, Bioorg. Med. Chem. Lett., 2000, 10, 407-409.
- (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 407-409
- Harris, J.M.¹ González-Bello, C.² Manthey, M.K.³ Coggins, J.R.⁴ Abell, C.⁵

12
- 0033574513
- M. Frederickson, E. J. Parker, A. R. Hawkins, J. R. Coggins and C. Abell, J. Org. Chem., 1999, 64, 2612-2613.
- (1999) J. Org. Chem. , vol.64 , pp. 2612-2613
- Frederickson, M.¹ Parker, E.J.² Hawkins, A.R.³ Coggins, J.R.⁴ Abell, C.⁵

13
- 0032979147
- D. G. Gourley, A. K. Shrive, I. Polikarpov, T. Krell, J. R. Coggins, A. R. Hawkins, N. W. Isaacs and L. Sawyer, Nat. Struct. Biol., 1999, 6, 521-525.
- (1999) Nat. Struct. Biol. , vol.6 , pp. 521-525
- Gourley, D.G.¹ Shrive, A.K.² Polikarpov, I.³ Krell, T.⁴ Coggins, J.R.⁵ Hawkins, A.R.⁶ Isaacs, N.W.⁷ Sawyer, L.⁸

14
- 0036223042
- A. W. Roszak, D. A. Robinson, T. Krell, I. S. Hunter, M. Fredrickson, C. Abell, J. R. Coggins and A. Lapthorn, Structure, 2002, 10, 493-503.
- (2002) Structure , vol.10 , pp. 493-503
- Roszak, A.W.¹ Robinson, D.A.² Krell, T.³ Hunter, I.S.⁴ Fredrickson, M.⁵ Abell, C.⁶ Coggins, J.R.⁷ Lapthorn, A.⁸

15
- 0029836953
- (a) S. B. Shuker, P. J. Hajduk, R. P. Meadows and S. W. Fesik, Science, 1996, 274, 1531-1534
- (1996) Science , vol.274 , pp. 1531-1534
- Shuker, S.B.¹ Hajduk, P.J.² Meadows, R.P.³ Fesik, S.W.⁴

16
- 16944365890
- (b) P. J. Hajduk, G. Sheppard, D. G. Nettesheim, E. T. Olejniczak, S. B. Shuker, R. P. Meadows, D. H. Steinman, G. M. Carrera, P. M. Marcotte, J. Severin, K. Walter, H. Smith, E. Gubbins, R. Simmer, T. F. Holzman, D. W. Morgan, S. K. Davidsen and S. W. Fesik, J. Am. Chem. Soc., 1997, 5818-5827.
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 5818-5827
- Hajduk, P.J.¹ Sheppard, G.² Nettesheim, D.G.³ Olejniczak, E.T.⁴ Shuker, S.B.⁵ Meadows, R.P.⁶ Steinman, D.H.⁷ Carrera, G.M.⁸ Marcotte, P.M.⁹ Severin, J.¹⁰ Walter, K.¹¹ Smith, H.¹² Gubbins, E.¹³ Simmer, R.¹⁴ Holzman, T.F.¹⁵ Morgan, D.W.¹⁶ Davidsen, S.K.¹⁷ Fesik, S.W.¹⁸

17
- 0028854034
- (a) G. Jones, P. Willet and R. C. Glen, J. Mol. Biol., 1995, 245, 43-53
- (1995) J. Mol. Biol. , vol.245 , pp. 43-53
- Jones, G.¹ Willet, P.² Glen, R.C.³

18
- 0031552362
- (b) G. Jones, P. Willet, R. C. Glen, A. R. Leach and R. Taylor, J. Mol. Biol., 1997, 267, 727-748.
- (1997) J. Mol. Biol. , vol.267 , pp. 727-748
- Jones, G.¹ Willet, P.² Glen, R.C.³ Leach, A.R.⁴ Taylor, R.⁵

19
- 0024974081
- T. Widlandski, S. L. Bender and J. R. Knowles, Biochemistry, 1989, 28, 7572-7582.
- (1989) Biochemistry , vol.28 , pp. 7572-7582
- Widlandski, T.¹ Bender, S.L.² Knowles, J.R.³

20
- 49549130554
- V. Van Rheenen, R. C. Kelly and D. Y. Cha, Tetrahedron Lett., 1976, 23, 1973-1976.
- (1976) Tetrahedron Lett. , vol.23 , pp. 1973-1976
- Van Rheenen, V.¹ Kelly, R.C.² Cha, D.Y.³

21
- 0024802464
- G. Poli, Tetrahedron Lett., 1989, 30, 7385-7388.
- (1989) Tetrahedron Lett. , vol.30 , pp. 7385-7388
- Poli, G.¹

22
- 0000948848
- J.-L. Montchamp, F. Tian, M. Hart and J. W. Frost, J. Org. Chem., 1996, 61, 3897-3899.
- (1996) J. Org. Chem. , vol.61 , pp. 3897-3899
- Montchamp, J.-L.¹ Tian, F.² Hart, M.³ Frost, J.W.⁴

23
- 0000370316
- F. Tian, J.-L. Montchamp and J. W. Frost, J. Org. Chem., 1996, 61, 7373-7381.
- (1996) J. Org. Chem. , vol.61 , pp. 7373-7381
- Tian, F.¹ Montchamp, J.-L.² Frost, J.W.³

24
- 0000497595
- R. Lakhamiri, P. Lhoste and D. Sinou, Tetrahedron Lett., 1989, 30, 4669-4672.
- (1989) Tetrahedron Lett. , vol.30 , pp. 4669-4672
- Lakhamiri, R.¹ Lhoste, P.² Sinou, D.³

25
- 77049143386
- M. Dixon, Biochem. J., 1953, 55, 170-171.
- (1953) Biochem. J. , vol.55 , pp. 170-171
- Dixon, M.¹

26
- 0141902217
- note
- SYBYL. 6.5. 1699 South Hanley Road, St. Louis, Missouri, 63144, USA: Tripos Inc.

27
- 0142006012
- note
- WebLab ViewerPro4.0.9685 Scranton Road, San Diego, CA 92121, USA: Accelrys Inc.

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