Interferon resistance of cutaneous T-cell lymphoma-derived clonal T-helper 2 cells allows selective viral replication

Blood

Volumn 97, Issue 2, 2001, Pages 523-527

  Dummer, Reinhard ^a   Döbbeling, Udo ^b   Geertsen, Ralf ^b   Willers, Jörg ^b   Burg, Günter ^b   Pavlovic, Jovan ^b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CD4 ANTIGEN; GAMMA INTERFERON; MESSENGER RNA; STAT1 PROTEIN;

ARTICLE; DRUG EFFECT; GENE EXPRESSION; HUMAN; HUMAN CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSCRIPTION; SEZARY SYNDROME; SKIN LYMPHOMA; T CELL LYMPHOMA; T LYMPHOCYTE; TH2 CELL; VESICULAR STOMATITIS VIRUS; VIRUS REPLICATION; VIRUS RESISTANCE;

EID: 0035863751     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V97.2.523     Document Type: Article

References (44)

1. The epidemiology of non-Hodgkin's lymphoma: Comparison of nodal and extra-nodal sites
2. A revised European-American classification of lymphoid neoplasms: A proposal from the international lymphoma study group
3. A randomized trial comparing combination electron-beam radiation and chemotherapy with topical therapy in the initial treatment of mycosis fungoides
4. Sézary syndrome's T-cell clones display T-helper 2 cytokines and express the accessory factor-1 (interferon γ receptor β chain)
5. A rational approach to the therapy of cutaneous T-cell lymphomas
6. Functional role of type I and type II interferons in antiviral defense
7. Cross talk between interferon-γ and -α/β signaling components in caveolar membrane domains
8. The expanding universe of T-cell subsets-TH1, TH2 and more
9. Pre-Sezary erythroderma evolving to Sezary syndrome: A report of seven cases
10. Mycosis fungoides: Clinical and histologic features, staging, evaluation, and approach to treatment
11. Profound deficiency in normal circulating T cells in erythrodermic cutaneous T-cell lymphoma
12. Diagnostic criteria in Sezary's syndrome: A multiparameter study of peripheral blood lymphocytes in 32 patients with erythroderma
13. Report of the committee on staging and classification of cutaneous T-cell lymphomas
14. - T cell frequency and polymerase chain reaction-based clonality assay correlate with stage in cutaneous T cell lymphomas
15. Failure of anti-T-cell receptor V-beta antibodies to consistently identity a malignant T-cell clone in Sezary syndrome
16. Flow cytometric detection of neoplastic T cells in patients with mycosis fungoides based on levels of T-cell receptor expression
17. Immunophenotypic identification of Sezary cells in peripheral blood
18. Prospective randomized multicenter clinical trial on the use of interferon-2a plus acitretin versus interferon-2a plus PUVA in patients with cutaneous T-cell lymphoma stages I and II
19. Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter
20. Basic local alignment search tool
21. Ligand-induced autoregulation of IFN-γ receptor β chain expression in T helper subsets
22. The human interferon alpha/beta receptor: Characterization and molecular cloning
23. The IFN gamma receptor: A paradigm for cytokine receptor signaling
24. JAK-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
25. Natural killer cell activity in head and neck cancer: A clinical assessment
26. The antiviral state induced by alpha interferon and gamma interferon requires transcriptionally active Stat1 protein
27. Resistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA protein
28. Human and mouse Mx proteins inhibit different steps of the influenza virus multiplication cycle
29. A continuous T-cell line from a patient with Sezary syndrome
30. Interferon-induced proteins and the antiviral state
31. Interferon-alpha resistance in a cutaneous T-cell lymphoma cell line is associated with lack of STAT1 expression
32. Immune response in mice that lack the interferon-γ receptor
33. Targeted disruption of the interferon-γ receptor 2 gene results in severe immune defects in mice
34. A human IFNGR1 Small deletion hotspot associated with dominant susceptibility to mycobacterial infection
35. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
36. JAKS and STATS-biological implications
37. Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice
38. Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein
39. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
40. ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
41. Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy
42. The molecular basis of viral oncolysis: Usurpation of the Ras signaling pathway by reovirus
43. Reovirus therapy of tumors with activated Ras pathway
44. Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus