Carbazochrome sodium sulfonate (AC-17) reverses endothelial barrier dysfunction through inhibition of phosphatidylinositol hydrolysis in cultured porcine endothelial cells

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 368, Issue 3, 2003, Pages 175-180

  Sendo, Toshiaki ^a   Itoh, Yoshinori ^a   Aki, Keisei ^a   Oka, Michiko ^b   Oishi, Ryozo ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Bradykinin; Carbazochrome sodium sulfonate; Permeability; Phosphoinositide hydrolysis; Porcine aortic endothelial cells; Thrombin; Tryptase

Indexed keywords

ACTIN; ALBUMIN; BRADYKININ; CADHERIN; CALCIMYCIN; CALCIUM IONOPHORE; CARBAZOCHROME SODIUM SULFONATE; EVANS BLUE; HEMOSTATIC AGENT; INOSITOL; INOSITOL TRISPHOSPHATE; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL; THROMBIN; TRYPTASE; UNCLASSIFIED DRUG; VASOACTIVE AGENT;

ANIMAL CELL; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL PERMEABILITY; CAPILLARY; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; HYDROLYSIS; IMMUNOFLUORESCENCE; NONHUMAN; STRESS FIBER; SWINE;

ACTINS; ADRENOCHROME; ANIMALS; ANTIGENS, CD; AORTA, THORACIC; BRADYKININ; CADHERINS; CAPILLARY PERMEABILITY; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; HEMOSTATICS; HYDROLYSIS; IONOPHORES; PHOSPHATIDYLINOSITOLS; PROTEIN KINASE C; SERINE ENDOPEPTIDASES; STRESS FIBERS; SWINE; TETRADECANOYLPHORBOL ACETATE; THROMBIN; TRYPTASES;

EID: 0141958896     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-003-0785-5     Document Type: Article

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