Chemoselective reduction of a lactam carbonyl group in the presence of a gem-dicarboxylate by sodium borohydride and iodine: A facile entry to N-aryl trisubstituted pyrroles

Tetrahedron Letters

Volumn 44, Issue 45, 2003, Pages 8229-8231

  Haldar, Pranab ^a   Ray, Jayanta K ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY   (India)

Author keywords

Chemoselective; Lactam; Pyrrole; Reduction

Indexed keywords

CARBONYL DERIVATIVE; DICARBOXYLIC ACID; ESTER DERIVATIVE; IODINE; LACTAM; PYRROLE DERIVATIVE; SODIUM BOROHYDRIDE;

ACIDITY; ARTICLE; CHEMICAL PROCEDURES; DECARBOXYLATION; HYDROLYSIS; ISOLATION PROCEDURE; LIQUID; REACTION ANALYSIS; REDUCTION; SYNTHESIS; TIME;

EID: 0141922953     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2003.09.085     Document Type: Article

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27. 4. The solvent was evaporated and the crude products were purified by column chromatography. Colourless viscous oily materials were identified by spectroscopic methods.
28. 3): δ 13.63, 60.24, 111.78, 112.19, 125.55, 127.09, 127.31, 127.64, 127.81, 128.05, 128.87, 129.54, 130.26, 131.90, 132.57, 135.02, 135.56, 140.31, 160.82.