A novel bioartificial liver containing small tissue fragments: Efficiency in the treatment of acute hepatic failure induced by carbon tetrachloride in rats

International Journal of Artificial Organs

Volumn 26, Issue 8, 2003, Pages 735-742

  Soloviev, V ^a   Hassan, A N E ^b   Akatov, Vladimir ^a   Lezhnev, E ^a   Ghaffar, T Y A ^b   Ghaffar, Y A ^b  

^a INSTITUTE OF THEORETICAL AND EXPERIMENTAL BIOPHYSICS   (Russian Federation)

^b Prof Ghaffar Charity Ctr for Liver   (Egypt)

Author keywords

Acute hepatic failure; Bioartificial liver; Tissue fragments

Indexed keywords

AMINO ACIDS; AMMONIA; ARTIFICIAL ORGANS; CARBON TETRACHLORIDE; EFFICIENCY; GLUCOSE; RATS; UREA;

ACUTE HEPATIC FAILURE; AMINO-ACIDS; BIOARTIFICIAL LIVER; HEMOPERFUSION; LACTATE DEHYDROGENASE; STATISTICALLY SIGNIFICANT DIFFERENCE; TISSUE FRAGMENT;

TISSUE;

ALANINE AMINOTRANSFERASE; AMINO ACID; AMMONIA; CARBON TETRACHLORIDE; COAGULATING AGENT; GLUCOSE; LACTATE DEHYDROGENASE; PHENYLALANINE; TYROSINE; UREA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINO ACID BLOOD LEVEL; AMMONIA BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL LIVER; BIOARTIFICIAL ORGAN; BIOREACTOR; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EXTRACORPOREAL CIRCULATION; GLUCOSE BLOOD LEVEL; HEMOPERFUSION; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER; LIVER FAILURE; MALE; NONHUMAN; RAT; SURVIVAL RATE; TOXICITY TESTING; TREATMENT OUTCOME; UREA BLOOD LEVEL;

EID: 0141921500     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.1177/039139880302600806     Document Type: Article

References (36)

1. Miyoshi H, Yanagi K, Fukuda H, Ohshima N. Long-term continuous culture of hepatocytes in a packed-bed reactor utilizing porous resin. Biotechnol Bioeng 1994; 43: 635-44.
2. Naruse K, Nagashima I, Sakai Y, et al. Efficacy of a bioreactor filled with porcine hepatocytes immobilized on nonwoven fabric for ex vivo direct hemoperfusion treatment of liver failure in pigs. Int J Artif Organs 1998; 22: 1031-7.
3. Nyberg SL, Shirabe K, Pashwa MV, et al. Extracorporeal application of a gel-entrapment, bioartificial liver: Demonstration of drug metabolism and other biochemical functions. Cell Transplant 1993; 2: 441-52.
4. Patzer JF 2nd, Mazariegos GV, Lopez R, et al. Novel bioartificial liver support system: Preclinical evaluation. Ann N Y Acad Sci 1999; 875: 340-52.
5. Shnyra A, Bocharov A, Bochkova N, Spirov V. Bioartificial liver using hepatocytes on biosilon microcarriers: Treatment of chemically induced acute hepatic failure in rats. Artif Organs 1991; 15: 189-97.
6. Shiraha H, Koide N, Hada H, et al. Improvement of serum amino acid profile in hepatic failure with the bioartificial liver using multicellular hepatocyte spheroids. Biotech Bioeng 1996; 50: 416-21.
7. Rozga J, Morsiani E, LePage E, Moscioni AD, Giorgio T, Demetriou AA. Isolated hepatocytes in a bioartificial liver: A single group view and experience. Biotech Bioeng 1994; 43: 645-53.
8. Ellis AJ, Hughes RD, Nicholl D, et al. Temporary extracorporeal liver support for severe acute alcoholic hepatitis using the Bio Logic-DT. Int J Artif Organs 1999; 22: 27-34.
9. Hughes RC, Stamatoglou SC. Adhesive interactions and the metabolic activity of hepatocytes. J Cell Sci 1987; 8(suppl): S273-91.
10. Moghe PV, Berthiaume F, Ezzell RM, Toner M, Tompkins RG, Yarmush ML. Culture matrix configuration and composition in the maintenance of hepatocyte polarity and function. Biomaterials 1996; 17: 373-85.
11. Okamoto M, Ishida Y, Keogh A, Strain A. Evaluation of the function of primary human hepatocytes co-cultured with the human hepatic stellate cell (HSC) line LI90. Int J Artif Organs 1998; 21: 353-9.
12. Guguen-Guillouzo C, Clement B, Baffet G, et al. Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type. Exp Cell Res 1983; 143: 47-54.
13. Nose Y, Mikami J, Kasai Y, Sasaki E, Agishi T, Danjo Y. An experimental artificial liver utilizing extracorporeal metabolism with sliced or granulated canine liver. Trans Am Soc Artif Intern Organs 1963; 9: 358-62.
14. Soyer T, Lempinen M, Walker JE, Supanwanid P, Eisenman B. Extracorporeal assist of anhepatic animals with liver slice perfusion. Am J Surg 1973; 126: 20-4.
15. Koshino I, Sakamoto H, Shinada Y, et al. Use of liver slices for an artificial liver. Trans Am Soc Artif Intern Organs 1979; 25: 493-6.
16. Lie TS, Jung V, Kachel F, Hohnke C, Lee KS. Successful treatment of hepatic coma by a new artificial liver device in the pig. Res Exp Med (Berl) 1985; 185: 483-94.
17. Clayton DF, Harrelson AL, Darnell JE Jr. Dependence of liver-specific transcription on tissue organization. Mol Cell Biol 1985; 5: 2623-32.
18. Padgham CR, Boyle CC, Wang XJ, Raleigh SM, Wright MC, Paine AJ. Alteration of transcription factor mRNAs during the isolation and culture of rat hepatocytes suggests the activation of a proliferative mode underlies their de-differentiation. Biochem Biophys Res Commun 1993; 197: 599-605.
19. Dogterom P. Development of a simple incubation system for metabolism studies with precision-cut liver slices. Drug Metab Dispos 1993; 21: 699-704.
20. Soloviev VV, Onishchenko NA, Akatov VS, Lezhnev EI. Functional activity of the hepatocytes in the liver fragments in vitro: Dependence on the size of fragments and on duration of their cultivation. (in Russian). Bull Eksp Biol Med 1997; 124: 406-8.
21. Soloviev VV, Akatov VS, Lezhnev EI. Study of functional activity of the hepatocytes in the liver fragments being in the novel bioreactor "bioartificial liver". (in Russian). Bull Eksp Biol Med 2000; 129: 698-700.
22. Wang D, Verney E, Sidransky H. Protective effect of tryptophan and cysteine against carbon tetrachloride-induced liver injury. Exp Mol Pathol 1985; 43: 364-74.
23. McIlwain H, Buddle HL. Techniques in tissue metabolism. 1. A mechanical chopper. Biochem J 1953; 53: 412-20.
24. Akatov VS, Ryabokon' EN, Muratov RM, Scopin II, Lezhnev EI. Study of fibroblast migration into tissue of heart valve leaflets in vitro. (in Russian). Tsitologiya 2000; 42: 57-61.
25. Mikami J, Mito M, Nashimura A, Sasaki E, Nose Y, Tedo I. Surgical treatment of acute liver failure. II. An experimental study of extracorporeal metabolism in the artificial liver using slices of canine liver. Jap J Gastroenterol 1959; 56: 1022-7.
26. Soyer T, Lempinen M, Eisenman B. In vitro extracorporal liver slices and cell suspensions for temporary hepatic support. Ann Surg 1973; 177: 393-401.
27. Catapano G. Mass transfer limitations to the performance of membrane bioartificial liver support devices. Int J Artif Organs 1996; 19: 18-35.
28. Soloviev VV, Akatov VS, Lezhnev EI. Bioreactor "bioartificial liver". (in Russian). Nauchnoe Priborostroenie 2000; 10: 77-83.
29. Barkhart KK, Hall AH, Gerace R, Rumack BH. Hyperbaric oxygen treatment for carbon tetrachloride poisoning. Drug Saf 1991; 6: 332-8.
30. 4 - Induced lipoperoxidation triggers a lethal defect in the liver plasma membranes. J Appl Toxicol 1990; 10: 23-7.
31. Flending LM, Calise F, Di Florio E, et al. Significantly improved survival time in pigs with complete liver ischemia treated with a novel bioartificial liver. Int J Artif Organs 1999; 22: 701-9.
32. Rossi-Fanelli F, Cascino A, Strom R, et al. Amino acids and hepatic encephalopathy. Prog Neurobiol 1987; 28: 277-301.
33. Schon MR, Heil W, Lemmens H, et al. Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio). Eur Surg Res 1999; 31: 230-9.
34. Podimova SD Liver diseases. Moscow. (in Russian). Medicine 1993; 62-9.
35. Dowling DJ, Mutimer DJ. Artificial support in acute liver failure. Eur J Gastroenterol Hepatol 1999; 11: 991-6.
36. Oda S, Hirasawa H, Shiga H, Nakanishi K, Matsuda K, Nakamura M. Continuous hemofiltration/hemodiafiltration in critical care. Ther Apher 2002; 6: 193-8.