Relevance and limitations of public databases for microarray design: A critical approach to gene predictions

Pharmacogenomics Journal

Volumn 3, Issue 4, 2003, Pages 235-241

  Lambert, Jean Charles ^a   Testa, E ^a   Cognat, V ^b   Soula, J ^b   Hot, D ^b   Lemoine, Y ^a   Gaypay, G ^c   Amouyel, P ^a  

^a INSTITUT PASTEUR DE LILLE   (France)

^b Parc Scientifique de Luminy   (France)

^c CENTRE NATIONAL DE SÉQUENÇAGE   (France)

Author keywords

Alzheimer's disease; Microarray; ORF; Prediction

Indexed keywords

COMPLEMENTARY DNA; OLIGONUCLEOTIDE;

ALZHEIMER DISEASE; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DNA MICROARRAY; EXON; GENE AMPLIFICATION; GENE EXPRESSION; GENE LOCUS; GENE PROBE; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC DATABASE; HUMAN; INTERNET; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; VALIDATION PROCESS;

DATABASES; DNA, COMPLEMENTARY; GENOME, HUMAN; HUMANS; MODELS, GENETIC; NATIONAL INSTITUTES OF HEALTH (U.S.); OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OPEN READING FRAMES; UNITED STATES;

EID: 0141813373     PISSN: 1470269X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.tpj.6500184     Document Type: Article

References (11)

1. Loring JF, Wen X, Lee JM, Seilhamer J, Somogyi R. A gene expression profile of Alzheimer's disease. DNA Cell Biol 2001; 20: 683-695.
2. Lambert JC, Pasquier F, Cottel D, Frigard B, Amouyel P, Chartier-Harlin MC. A new polymorphism in the APOE promoter associated with the risk of developing Alzheimer's disease. Hum Mol Genet 1998; 7: 533-540.
3. Theuns J, Van Broeckhoven C. Transcriptional regulation of Alzheimer's disease genes: implications for susceptibility. Hum Mol Genet 2000; 9: 2383-2394.
4. Riazanskaia N, Lukiw WJ, Grigorenko A, Korovaitseva G, Dvoryanchikov G, Moliaka Y et al. Regulatory region variability in the human presenilin-2 (PSEN2) gene: potential contribution to the gene activity and risk for AD. Mol Psychiatry 2002; 7: 891-898.
5. Wavrant-De Vrieze F, Crook R, Holmans P, Kehoe P, Owen MJ, Williams J et al. Genetic variability in the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer's disease. Neurosci Lett 1999; 269: 67-70.
6. Kehoe P, Wavrant-De Vrieze F, Crook R, Wu WS, Holmans P, Fenton I et al. A full genome scan for late onset Alzheimer's disease. Hum Mol Genet 1999; 8: 237-245.
7. Myers A, Wavrant De-Vrieze F, Holmans P, Hamshere M, Crook R, Compton D et al. Full genome screen for Alzheimer disease: stage II analysis. Am J Med Genet 2002; 114: 235-244.
8. Pericak-Vance MA, Grubber J, Bailey LR, Hedges D, West S, Santoro L et al. Identification of novel genes in late-onset Alzheimer's disease. Exp Gerontol 2000; 35: 1343-1352.
9. Olson JM, Goddard KA, Dudek DM. A second locus for very-late-onset Alzheimer disease: a genome scan reveals linkage to 20p and epistasis between 20p and the amyloid precursor protein region. Am J Hum Genet 2002; 71: 154-161.
10. Yeh RF, Lim LP, Burge CB. Computational inference of homologous gene structures in the human genome. Genome Res 2001; 11: 803-816.
11. Pruitt KD, Maglott DR. RefSeq and LocusLink: NCBI gene-centered resources. Nucleic Acids Res 1999; 29: 137-140.