메뉴 건너뛰기




Volumn 10, Issue 9, 2003, Pages 689-695

Hepatoma cell-specific ganciclovir-mediated toxicity of a lentivirally transduced HSV-TkEGFP fusion protein gene placed under the control of rat alpha-fetoprotein gene regulatory sequences

Author keywords

Alpha fetoprotein; Hepatocellular carcinoma; HSV TkEGFP; Lentiviral vector

Indexed keywords

ALPHA FETOPROTEIN; EPIDERMAL GROWTH FACTOR; GANCICLOVIR; GREEN FLUORESCENT PROTEIN; HERPES SIMPLEX VIRUS THYMIDINE KINASE ENHANCED GREEN FLUORESCENT FUSION PROTEIN; HYBRID PROTEIN; LENTIVIRUS VECTOR; THYMIDINE KINASE; UNCLASSIFIED DRUG;

EID: 0141788260     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700621     Document Type: Article
Times cited : (25)

References (27)
  • 1
    • 0034090264 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Okuda K. Hepatocellular carcinoma. J Hepatol. 2000;32:225-237.
    • (2000) J Hepatol , vol.32 , pp. 225-237
    • Okuda, K.1
  • 2
    • 0033428642 scopus 로고    scopus 로고
    • Natural history and pathogenesis of hepatitis C virus related hepatocellular carcinoma
    • Colombo M. Natural history and pathogenesis of hepatitis C virus related hepatocellular carcinoma. J Hepatol. 1999;31:25-30.
    • (1999) J Hepatol , vol.31 , pp. 25-30
    • Colombo, M.1
  • 3
    • 0032145740 scopus 로고    scopus 로고
    • Impact of HBV, HCV and GBV-C/HGV on hepatocellular carcinomas in Europe: Results of a European concerted action
    • Brechot C, Jaffredo F, Lagorce D, et al. Impact of HBV, HCV and GBV-C/ HGV on hepatocellular carcinomas in Europe: results of a European concerted action. J Hepatol. 1998;29:173-183.
    • (1998) J Hepatol , vol.29 , pp. 173-183
    • Brechot, C.1    Jaffredo, F.2    Lagorce, D.3
  • 4
    • 0033545541 scopus 로고    scopus 로고
    • Rising incidence of hepatocellular carcinoma in the United States
    • El-Serag HB, Mason AC. Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med. 1999;340:745-750.
    • (1999) N Engl J Med , vol.340 , pp. 745-750
    • El-Serag, H.B.1    Mason, A.C.2
  • 5
    • 0032899160 scopus 로고    scopus 로고
    • Modeling the hepatitis C virus epidemic in France
    • Deuffic S, Buffat L, Poynard T, et al. Modeling the hepatitis C virus epidemic in France. Hepatology. 1999;29:1596-1601.
    • (1999) Hepatology , vol.29 , pp. 1596-1601
    • Deuffic, S.1    Buffat, L.2    Poynard, T.3
  • 6
    • 0025891345 scopus 로고
    • Surgical treatment of hepatocellular carcinoma: Experience with liver resection and transplantation in 198 patients
    • Ringe B, Pichlmayr R, Wittekind C, et al. Surgical treatment of hepatocellular carcinoma: experience with liver resection and transplantation in 198 patients. World J Surg. 1991;15:270-285.
    • (1991) World J Surg , vol.15 , pp. 270-285
    • Ringe, B.1    Pichlmayr, R.2    Wittekind, C.3
  • 7
    • 0345299824 scopus 로고    scopus 로고
    • Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis
    • Mazzaferro V, Regalia E, Doci R, et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med. 1996;334:693-699.
    • (1996) N Engl J Med , vol.334 , pp. 693-699
    • Mazzaferro, V.1    Regalia, E.2    Doci, R.3
  • 8
    • 0027170844 scopus 로고
    • Liver resection versus transplantation for hepatocellular carcinoma in cirrhotic patients
    • Bismuth H, Chiche L, Adam R, et al. Liver resection versus transplantation for hepatocellular carcinoma in cirrhotic patients. Ann Surg. 1993;218:145-151.
    • (1993) Ann Surg , vol.218 , pp. 145-151
    • Bismuth, H.1    Chiche, L.2    Adam, R.3
  • 9
    • 0032920252 scopus 로고    scopus 로고
    • Recurrence patterns of hepatocellular and fibrolamellar carcinoma after liver transplantation
    • Schlitt HJ, Neipp M, Weimann A, et al. Recurrence patterns of hepatocellular and fibrolamellar carcinoma after liver transplantation. J Clin Oncol. 1999;17:324-331.
    • (1999) J Clin Oncol , vol.17 , pp. 324-331
    • Schlitt, H.J.1    Neipp, M.2    Weimann, A.3
  • 10
    • 0033975496 scopus 로고    scopus 로고
    • The potential of gene therapy in the treatment of hepatocellular carcinoma
    • Qian C, Drozdzik M, Caselmann WH, et al. The potential of gene therapy in the treatment of hepatocellular carcinoma. J Hepatol. 2000;32:344-351.
    • (2000) J Hepatol , vol.32 , pp. 344-351
    • Qian, C.1    Drozdzik, M.2    Caselmann, W.H.3
  • 11
    • 0034652614 scopus 로고    scopus 로고
    • Evaluation of HSV-tk gene therapy in a rat model of chemically induced hepatocellular carcinoma by intratumoral and intrahepatic artery routes
    • Gerolami R, Cardoso J, Lewin M, et al. Evaluation of HSV-tk gene therapy in a rat model of chemically induced hepatocellular carcinoma by intratumoral and intrahepatic artery routes. Cancer Res. 2000;60:993-1001.
    • (2000) Cancer Res , vol.60 , pp. 993-1001
    • Gerolami, R.1    Cardoso, J.2    Lewin, M.3
  • 12
    • 0030636585 scopus 로고    scopus 로고
    • Liver-associated toxicity of the HSV-tk/GCV approach and adenoviral vectors
    • Brand K, Arnold W, Bartels T, et al. Liver-associated toxicity of the HSV-tk/GCV approach and adenoviral vectors. Cancer Gene Ther. 1997;4:9-16.
    • (1997) Cancer Gene Ther , vol.4 , pp. 9-16
    • Brand, K.1    Arnold, W.2    Bartels, T.3
  • 13
    • 1642586736 scopus 로고    scopus 로고
    • Transduction efficacy, antitumoral effect, and toxicity of adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir therapy of hepatocellular carcinoma: The woodchuck animal model
    • Bilbao R, Gerolami R, Bralet MP,et al. Transduction efficacy, antitumoral effect, and toxicity of adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir therapy of hepatocellular carcinoma: the woodchuck animal model. Cancer Gene Therapy. 2000;7:657-662.
    • (2000) Cancer Gene Therapy , vol.7 , pp. 657-662
    • Bilbao, R.1    Gerolami, R.2    Bralet, M.P.3
  • 14
    • 0031788861 scopus 로고    scopus 로고
    • Tumor cell-specific transgene expression prevents liver toxicity of the adeno-HSVtk/GCV approach
    • Brand K, Loser P, Arnold W, et al. Tumor cell-specific transgene expression prevents liver toxicity of the adeno-HSVtk/GCV approach. Gene Therapy. 1998;5:1363-1371.
    • (1998) Gene Therapy , vol.5 , pp. 1363-1371
    • Brand, K.1    Loser, P.2    Arnold, W.3
  • 15
    • 0033775626 scopus 로고    scopus 로고
    • Gene transfer to hepatocellular carcinoma: Transduction efficacy and transgene expression kinetics by using retroviral and lentiviral vectors
    • Gerolami R, Uch R, Jordier F, et al. Gene transfer to hepatocellular carcinoma: transduction efficacy and transgene expression kinetics by using retroviral and lentiviral vectors. Cancer Gene Ther. 2000;7:1286-1292.
    • (2000) Cancer Gene Ther , vol.7 , pp. 1286-1292
    • Gerolami, R.1    Uch, R.2    Jordier, F.3
  • 16
    • 0033986340 scopus 로고    scopus 로고
    • Efficient lentiviral transduction of liver requires cell cycling in vivo
    • Park F, Ohashi K, Chiu W, et al. Efficient lentiviral transduction of liver requires cell cycling in vivo. Nat Genet. 2000;24:49-52.
    • (2000) Nat Genet , vol.24 , pp. 49-52
    • Park, F.1    Ohashi, K.2    Chiu, W.3
  • 17
    • 0036297393 scopus 로고    scopus 로고
    • Tumor markers in early diagnosis, follow-up and management of patients with hepatocellular carcinoma
    • Fujiyama S, Tanaka M, Maeda S, et al. Tumor markers in early diagnosis, follow-up and management of patients with hepatocellular carcinoma. Oncology. 2002;62(Suppl 1):57-63.
    • (2002) Oncology , vol.62 , Issue.SUPPL. 1 , pp. 57-63
    • Fujiyama, S.1    Tanaka, M.2    Maeda, S.3
  • 18
    • 0029967430 scopus 로고    scopus 로고
    • Correction of ornithine transcarbamylase deficiency in adult spf(ash) mice and in OTC-deficient human hepatocytes with recombinant adenoviruses bearing the CAG promoter
    • Kiwaki K, Kanegae Y, Saito I, et al. Correction of ornithine transcarbamylase deficiency in adult spf(ash) mice and in OTC-deficient human hepatocytes with recombinant adenoviruses bearing the CAG promoter. Hum Gene Ther. 1996;7:821-830.
    • (1996) Hum Gene Ther , vol.7 , pp. 821-830
    • Kiwaki, K.1    Kanegae, Y.2    Saito, I.3
  • 19
    • 0032978712 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
    • Zufferey R, Donello JE, Trono D, et al. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J Virol. 1999;73:2886-2892.
    • (1999) J Virol , vol.73 , pp. 2886-2892
    • Zufferey, R.1    Donello, J.E.2    Trono, D.3
  • 20
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini L, Blomer U, Gallay P, et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science. 1996;272:263-267.
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1    Blomer, U.2    Gallay, P.3
  • 21
    • 0028808656 scopus 로고
    • Adenovirus-mediated gene therapy of hepatocellular carcinoma using cancer-specific gene expression
    • Kaneko S, Hallenbeck P, Kotani T, et al. Adenovirus-mediated gene therapy of hepatocellular carcinoma using cancer-specific gene expression. Cancer Res. 1995;55:5283-5287.
    • (1995) Cancer Res , vol.55 , pp. 5283-5287
    • Kaneko, S.1    Hallenbeck, P.2    Kotani, T.3
  • 22
    • 0029759957 scopus 로고    scopus 로고
    • In vitro and in vivo hepatoma cell specific expression of a gene transferred with an adenoviral vector
    • Arbuthnot P, Bralet M, LeJossic C, et al. In vitro and in vivo hepatoma cell specific expression of a gene transferred with an adenoviral vector. Hum Gene Ther. 1996;7:1503-1514.
    • (1996) Hum Gene Ther , vol.7 , pp. 1503-1514
    • Arbuthnot, P.1    Bralet, M.2    LeJossic, C.3
  • 23
    • 0028880994 scopus 로고
    • Hepatoma cell-specific expression of a retrovirally transferred gene is achieved by alpha-foetoprotein but not insulin-like growth factor II regulatory sequences
    • Arbuthnot P, Bralet M-P, Thomassin H, et al. Hepatoma cell-specific expression of a retrovirally transferred gene is achieved by alpha-foetoprotein but not insulin-like growth factor II regulatory sequences. Hepatology. 1995;22:1788-1796.
    • (1995) Hepatology , vol.22 , pp. 1788-1796
    • Arbuthnot, P.1    Bralet, M.-P.2    Thomassin, H.3
  • 24
    • 0031043426 scopus 로고    scopus 로고
    • In vivo gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by adenovirus-mediated transfer of cytosine deaminase gene
    • Kanai F, Lan KH, Shiratori Y, et al. In vivo gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by adenovirus-mediated transfer of cytosine deaminase gene. Cancer Res. 1997;57:461-465.
    • (1997) Cancer Res , vol.57 , pp. 461-465
    • Kanai, F.1    Lan, K.H.2    Shiratori, Y.3
  • 25
    • 15844416306 scopus 로고    scopus 로고
    • Gene therapy for alpha-fetoprotein-producing human hepatoma cells by adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene
    • Kanai F, Shiratori Y, Yoshida Y, et al. Gene therapy for alpha-fetoprotein-producing human hepatoma cells by adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene. Hepatology. 1996;23:1359-1368.
    • (1996) Hepatology , vol.23 , pp. 1359-1368
    • Kanai, F.1    Shiratori, Y.2    Yoshida, Y.3
  • 26
    • 0030871467 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus-induced carcinoma as a relevant natural model for therapy of human hepatoma
    • Gouillat C, Manganas D, Zoulim F, et al. Woodchuck hepatitis virus-induced carcinoma as a relevant natural model for therapy of human hepatoma. J Hepatol. 1997;26:1324-1330.
    • (1997) J Hepatol , vol.26 , pp. 1324-1330
    • Gouillat, C.1    Manganas, D.2    Zoulim, F.3
  • 27
    • 0034186366 scopus 로고    scopus 로고
    • Prodrug activation enzymes in cancer gene therapy
    • Aghi M, Hochberg F, Breakefield XO. Prodrug activation enzymes in cancer gene therapy. J Gene Med. 2000;2:148-164.
    • (2000) J Gene Med , vol.2 , pp. 148-164
    • Aghi, M.1    Hochberg, F.2    Breakefield, X.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.