L-arginine transport across the basal plasma membrane of the syncytiotrophoblast of the human placenta from normal and preeclamptic pregnancies

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 9, 2003, Pages 4287-4292

  Speake, P F ^a   Glazier, J D ^a   Ayuk, P T Y ^b   Reade, M ^c   Sibley, C P ^a   D'Souza, S W ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSPORTER; ARGININE; NITRIC OXIDE SYNTHASE;

ARTICLE; CAPILLARY ENDOTHELIUM; CELL MEMBRANE; CELL VACUOLE; CONTROLLED STUDY; FETOPLACENTAL UNIT; HORMONE RECEPTOR TRANSLOCATION; HORMONE SENSITIVITY; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN TRANSPORT; SCANNING ELECTRON MICROSCOPY; SYNCYTIOTROPHOBLAST; WESTERN BLOTTING;

ADULT; ALKALINE PHOSPHATASE; ARGININE; BIOLOGICAL TRANSPORT, ACTIVE; BLOTTING, WESTERN; CATIONIC AMINO ACID TRANSPORTER 1; CELL MEMBRANE; DENSITOMETRY; FEMALE; HUMANS; KINETICS; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TROPHOBLASTS;

EID: 0141787943     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-030067     Document Type: Article

References (46)

1. Roberts JM 1994 Pregnancy-related hypertension. In: Creasy RK, Resnik R, eds. Maternal-fetal medicine: principles and practice. Philadelphia: Saunders; 804-843
2. Martin AM, Bindra R, Curcio P, Cicero S, Nicolaides KH 2001 Screening for pre-eclampsia and fetal growth restriction by uterine artery Doppler at 11-14 weeks of gestation. Ultrasound Obstet Gynecol 18:583-586
3. Palmer RM, Ferrige AG, Moncada S 1987 Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327:524-526
4. Hull AD, White CR, Pearce WJ 1994 Endothelium-derived relaxing factor and cyclic GMP-dependent vasorelaxation in human chorionic plate arteries. Placenta 115:365-375
5. Myatt L, Brockman DE, Eis AL, Pollock JS 1993 Immunohistochemical localization of nitric oxide synthase in the human placenta. Placenta 14:487-495
6. Ramsey B, deBelder A, Campbell S, Moncada S, Martin JF 1994 A nitric oxide doner improves uterine artery diastolic blood flow in normal early pregnancy and in women at high risk of pre-eclampsia. Eur J Clin Invest 24:76-78
7. Sooranna SR, Morris NH, Steer PJ 1995 Placental nitric oxide metabolism. Reprod Fertil Dev 7:1525-1531
8. Brennecke SP, Gude NM, Di Iulio JL, King RG 1997 Reduction of placental nitric oxide synthase activity in pre-eclampsia. Clin Sci 93:51-55
9. Beinder E, Mohaupt MG, Schlembach D, Fischer T, Sterzel RB, Lang N, Baylis C 1999 Nitric oxide synthase activity and Doppler parameters in the fetoplacental and uteroplacental circulation in preeclampsia. Hypertens Pregnancy 18:115-127
10. Lyall F, Young A, Greer IA 1995 Nitric oxide concentrations are increased in the fetoplacental circulation in preeclampsia. Am J Obstet Gynecol 173:714-718
11. Norris LA, Higgins JR, Darling MR, Walshe JJ, Bonnar J 1999 Nitric oxide in the uteroplacental, fetoplacental, and peripheral circulations in preeclampsia. Obstet Gynecol 93:958-963
12. Myatt L, Rosenfield RB, Eis AL, Brockman DE, Greer IA, Lyall F 1996 Nitrotyrosine residues in placenta. Evidence of peroxynitrite formation and action. Hypertension 28:488-493
13. Myatt L, Eis AL, Brockman DE, Greer IA, Lyall F 1997 Endothelial nitric oxide synthase in placental villous tissue from normal, pre-eclamptic and intrauterine growth restricted pregnancies. Hum Reprod 12:167-172
14. Palmer RM, Ashton DS, Moncada S 1988 Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 333:664-666
15. Hardy TA, May JM 2002 Coordinate regulation of L-arginine uptake and nitric oxide synthase activity in cultured endothelial cells. Free Radic Biol Med 32:122-131
16. Closs EI, Scheld J-S, Sharafi M, Forstermann U 2000 Substrate supply for nitric-oxide synthase in macrophages and endothelial cells: role of cationic amino acid transporters. Mol Pharmacol 57:68-74
17. Ayuk PT, Sibley CP, Donnai P, D'Souza S, Glazier JD 2000 Development and polarization of cationic amino acid transporters and regulators in the human placenta. Am J Physiol 278:C1162-C1171
18. Kamath SG, Furesz TC, Way BA, Smith CH 1999 Identification of three cationic amino acid transporters in placental trophoblast: cloning, expression, and characterization of hCAT-1. J Membr Biol 171:55-62
19. Wolf S, Janzen A, Vekony N, Martine U, Strand D, Closs EI 2002 Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity. Biochem J 364:767-775
20. Deves R, Boyd CAR 2000 Surface antigen CD98(4F2): Not a single membrane protein, but a family of proteins with multiple functions. J Membr Biol 173:165-177
21. Kudo Y, Boyd CAR 2000 Heterodimeric amino acid transporters: expression of heavy but not light chains of CD98 correlates with induction of amino acid transport systems in human placental trophoblast. J Physiol 523:13-18
22. Ayuk PT, Theophanous D, D'Souza S, Sibley CP, Glazier JD 2002 L-arginine transport by the microvillous plasma membrane of the syncytiotrophoblast from human placenta in relation to nitric oxide production: effects of gestation, pre-eclampsia and intra-uterine growth restriction. J Clin Endocrinol Metab 87:747-751
23. Davey DA, MacGillivray I 1988 The classification and definition of the hypertensive disorders of pregnancy. Am J Obstet Gynecol 158:892-898
24. Redman CWG, Jefferies M 1988 Revised definition of pre-eclapmsia. Lancet 8589:809-812
25. Kelley LK, Smith CH, King BF 1983 Isolation and partial characterization of the basal-cell membrane of human placental trophoblast. Biochim Biophys Acta 734:91-98
26. Glazier J, Ayuk P, Grey AM, Sides K 1998 Syncytiotrophoblast basal plasma membrane isolation. Placenta 19:443-444
27. Whitsett J, Johnson C, Noguchi A, Darovec-Beckerman C, Costellc M 1980 Beta adrenergic receptors and catecholamine-sensitive adenylate cyclase of the human placenta. J Clin Endocrinol Metab 50:27-32
28. Jones CJP, Fox H 1976 An ultrahistochemical study of the distribution of acid and alkaline phosphatases in placentae from normal and complicated pregnancies. J Pathol 118:143-151
29. + uptake by human placental microvillus membrane vesicles prepared by three different methods. Biochim Biophys Acta 945:127-134
30. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ 1951 Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
31. Deves R, Boyd CAR 1998 Transporters for cationic amino acids in animal cells: discovery, structure, and function. Physiol Rev 78:487-545
32. Reade MC, Clark MF, Young JD, Boyd CA 2002 Increased cationic amino acid flux through a newly expressed transporter in cells overproducing nitric oxide from patients with septic shock. Clin Sci 102:645-650
33. Zharikov SI, Sigova AA, Chen S, Bubb MR, Block ER 2001 Cytoskeletal regulation of the L-arginine/NO pathway in pulmonary artery endothelial cells. Am J Physiol 280:L465-L473
34. Smith CH, Kamath SG 1994 Trophoblast basal and microvillous membrane isolation. Placenta 15:779-781
35. Furesz TC, Heath-Monnig E, Kamath SG, Smith CH 2002 Lysine uptake by cloned hCAT-2B: comparison with hCAT-1 and with trophoblast surface membranes. J Membr Biol 189:27-33
36. Jansson T, Scholtbach V, Powell TL 1998 Placental transport of leucine and lysine is reduced in intrauterine growth restriction. Pediatr Res 44:532-537
37. Graf P, Forstermann U, Closs EI 2001 The transport activity of the human cationic amino acid transporter hCAT-1 is downregulated by activation of protein kinase C. Br J Pharmacol 132. 1:193-200
38. Palacin M, Estevez R, Bertran J, Zorzano A 1998 Molecular biology of mammalian plasma membrane amino acid transporters. Physiol Rev 78:969-1054
39. Pearse WH, Sornson H 1969 Free amino acids of normal and abnormal human placenta. Am J Obstet Gynecol 105:696-700
40. Cetin I, Ronzoni S, Marconi AM, Perugino G, Corbetta C, Battaglia FC, Pardi G 1996 Maternal concentrations and fetal-maternal concentration differences of plasma amino acids in normal and intrauterine growth-restricted pregnancies. Am J Obstet Gynecol 174:1575-1583
41. Greenwood SL, Clarson LH, Sides MK, Sibley CP 1996 Membrane potential difference and intracellular cation concentrations in human placental trophoblast cells in culture. J Physiol 492:629-640
42. Bogle RG, Baydoun AR, Pearson JD, Mann GE 1996 Regulation of L-arginine transport and nitric oxide release in superfused porcine aortic endothelial cells. J Physiol 490:229-241
43. Hyatt SL, Aulak KS, Malandro M, Kilberg MS, Hatzoglou M 1997 Adaptive regulation of the cationic amino acid transporter-1 (Cat-1) in Fao cells. J Biol Chem 272:19951-19957
44. Sacks G, P, Studena K, Sargent K, Redman CW 1998 Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis. Am J Obstet Gynecol 179:80-86
45. Boyd CA, Crawford DH 1992 Activation of cationic amino acid transport through system y+ correlates with expression of the T-cell early antigen gene in human lymphocytes. Pflugers Arch 422:87-89
46. Dye JF, Vause S, Clark P, Firth JA, Johnston T, D'Souza S, Sibley CP, Glazier J 2001 Arginine transport by cultured human placental microvascular endothelial cells from normal and pre-eclamptic pregnancies. Placenta 22:A.57