Reduction of placental nitric oxide synthase activity in pre-eclampsia

Clinical Science

Volumn 93, Issue 1, 1997, Pages 51-55

  Brennecke, S P ^a   Gude, N M ^a   Di Iulio, J L ^a   King, R G ^b  

^a ROYAL WOMEN'S HOSPITAL   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Nitric oxide synthase; Placenta; Pre eclampsia

Indexed keywords

ARGININE; CALCIUM CHLORIDE; CALMODULIN; CITRULLINE; FLAVINE ADENINE NUCLEOTIDE; MAGNESIUM ACETATE; MAGNESIUM DERIVATIVE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PLACENTA ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TETRAHYDROBIOPTERIN; UNCLASSIFIED DRUG; VASODILATOR AGENT;

ARTICLE; CESAREAN SECTION; CHEMICAL REACTION KINETICS; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; ISOTOPE LABELING; MICHAELIS CONSTANT; PREECLAMPSIA; PRIORITY JOURNAL; VAGINAL DELIVERY;

EID: 0030753151     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0930051     Document Type: Article

References (41)

1. Cooper DW, Brennecke SP, Wilton AN. Genetics of pre-eclampsia. Hypertension in Pregnancy 1993; 12: 1-23.
2. Roberts JM, Redman CWG. Pre-eclampsia: more than pregnancy-induced hypertension. Lancet 1993; 341: 1447-51.
3. Brown MA. The physiology of pre-eclampsia. Clin Exp Pharmacol Physiol 1995; 22: 781-91.
4. Kopp L, Paradiz G, Tucci JR. Urinary excretion of cyclic 3′,5′-adenosine monophosphate and cyclic 3′,5′-guanosine monophosphate during and after pregnancy. J Clin Endocrinol Metab 1977; 44: 590-4.
5. Conrad KP, Joffe GM, Kruszyna H. Identification of increased nitric oxide biosynthesis during pregnancy in rats. FASEB J 1993; 7: 566-71.
6. Weiner CP, Knowles RG, Moncada S. Induction of nitric oxide synthases early in pregnancy. Am J Obstet Gynecol 1994; 171: 838-43.
7. McLaughlin MK, Conrad, KP. Nitric oxide biosynthesis during pregnancy: implications for circulatory changes. Clin Exp Pharmacol Physiol 1995; 22: 164-71.
8. Morris NH, Eaton BM, Dekker G. Nitric oxide, the endothelium, pregnancy and pre-eclampsia. Br J Obstet Gynaecol 1996; 103: 4-15.
9. Gude NM, King RG, Brennecke SP. Role of endothelium-derived nitric oxide in maintenance of low fetal vascular resistance in placenta. Lancet 1990; 336: 1589-90.
10. 2 receptor-mediated vasoconstriction in the fetal vessels of the human perfused placenta. Placenta 1992; 13: 597-605.
11. Myatt L, Brewer A, Brockman DE. The action of nitric oxide in the perfused human fetal-placental circulation. Am J Obstet Gynecol 1991; 164: 687-92.
12. Seligman SP, Buyon JP, Clancy RM, Young, BK, Abramson SB. The role of nitric oxide in the pathogenesis of pre-eclampsia. Am J Obstet Gynecol 1994; 171: 944-8.
13. Curtis NE, Gude NM, King RG, Marriot PJ, Rook TJ, Brennecke SP. Nitric oxide metabolites in normal human pregnancy and pre-eclampsia. Hypertens Preg 1995; 14: 339-49.
14. Barton JR, Sibai BM, Ahokas RA, Whybrew WD, Mercer BM. Magnesium sulfate therapy in pre-eclampsia is associated with increased urinary cyclic guanosine monophosphate excretion. Am J Obstet Gynecol 1992; 167: 931-4.
15. Cameron IT, Van Paperndorp CL, Palmer RMJ, Smith SK, Moncada S. Relationship between nitric oxide synthesis and increase in systolic blood pressure in women with hypertension in pregnancy. Hypertens Preg 1993; 12: 85-92.
16. Brown MA, Tibben E, Zammit VC, Cario GM, Carlton MA. Nitric oxide excretion in normal and hypertensive pregnancies. Hypertens Preg 1995; 14: 319-26.
17. Pinto A, Sorrentino R, Sorrentino P, et al. Endothelial-derived relaxing factor released by endothelial cells of human umbilical vessels and its impairment in pregnancy-induced hypertension. Am J Obstet Gynecol 1991; 164: 507-13.
18. Akar F, Ark M, Uydes S, et al. Nitric oxide production by human umbilical vessels in severe pre-eclampsia. J Hypertens 1994; 12: 1235-41.
19. Wang Y, Walsh SW, Parnell R, Han J. Placental production of nitric oxide and endothelin in normal and preeclamptic pregnancies. Hypertens Preg 1994; 13: 171-8.
20. Orpana AK, Avela K, Ranta V, Viinikka L, Ylikorkala O. The calcium-dependent nitric oxide production of human vascular endothelial cells in preeclampsia. Am J Obstet Gynecol 1996; 174: 1056-60.
21. Yallampalli C, Garfield RE. Inhibition of nitric oxide synthesis in rats during pregnancy produces signs similar to those of pre-eclampsia. Am J Obstet Gynecol 1993; 169: 1316-20.
22. Diket AL, Pierce MR, Munshi UK, et al. Nitric oxide inhibition causes growth retardation and hind-limb disruption in rats. Am J Obstet Gynecol 1994; 171: 1243-50.
23. Griffith OW, Stuehr DJ. Nitric oxide synthases: properties and catalytic mechanism. Ann Rev Physiol 1995; 57: 707-36.
24. Myatt L, Brockman DE, Langdon G, Pollock JS. Constitutive calcium-dependent isoform of nitric oxide synthase in the human placental villous vascular tree. Placenta 1993; 14: 373-83.
25. Garvey EP, Tuttle JV, Covington K, et al. Purification and characterization of the constitutive nitric oxide synthase from human placenta. Arch Biochem Biophys 1994; 311: 235-41.
26. Gude NM, Di Iulio J, Brennecke SP, King RG. Human placental villous nitric oxide synthase activity. Pharmacol Commun 1994; 4: 163-71.
27. Conrad KP, Vill M, McGuire PG, Dail WG, Davis AK. Expression of nitric oxide synthase by syncytiotrophoblast in human placenta villi. FASEB J 1993; 7: 1269-76.
28. Buttery LDK, McCarthy A, Springall DR, et al. Endothelial nitric oxide synthase in the human placenta: regional distribution and proposed regulatory role at the feto-maternal interface. Placenta 1994; 15: 257-65.
29. Giles W, O'Callaghan S, Read M, Gude N, King R, Brennecke S. Placental nitric oxide synthase activity and abnormal umbilical artery flow velocity waveforms. Obstet Gynecol 1997; 89: 49-52.
30. Ghabour MS, Eis ALW, Brockman DE, Pollock JS, Myatt L. Immunohistochemical characterization of placental nitric oxide synthase expression in preeclampsia. Am J Obstet Gynecol 1995; 173: 687-94.
31. Di Iulio JL, Gude NM, King RG, Brennecke SP. Human placental and fetal membrane nitric oxide synthase activity before, during and after labour at term. Reprod Fertil Dev 1995; 7: 1505-8.
32. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
33. Yui Y, Hattori R, Kosuga K, Eizawa H, Hiki K, Kawai C. Purification of nitric oxide synthase from rat macrophages. J Biol Chem 1991; 260: 12544-7.
34. Morris NM, Sooranna SR, Learmont JG, et al. Nitric oxide synthase activities in placental tissue from normotensive, pre-eclamptic and growth retarded pregnancies. Br J Obstet Gynaecol 1995; 102: 711-14.
35. Conrad KP, Davis AK. Nitric oxide synthase activity in placentae from women with pre-eclampsia. Placenta 1995; 16: 691-9.
36. Rutherford RAO, McCarthy A, Sullivan MHF, Elder MG, Polak JM, Wharton J. Nitric oxide synthase in human placenta and umbilical cord from normal, intrauterine growth-retarded and pre-eclamptic pregnancies. Br J Pharmacol 1995; 116: 3099-109.
37. Gude NM. Endothelium-derived relaxing factor (nitric oxide) and the placenta. In: Rice GE, Brennecke SP, eds. Molecular aspects of placental and fetal membrane autacoids. Florida: CRC Press, 1993: 263-276.
38. Jones CJP, Fox H. An ultrastructural and ultrahistochemical study of the human placenta in maternal pre-eclampsia. Placenta 1980; 1: 61-76.
39. Kim N, Varda Y, Padma-Nathan H, Daley J, Goldstein I, Saenz de Tejada I. Oxygen tension regulates the nitric oxide pathway: physiological role in penile erection. J Clin Invest 1993; 91: 437-42.
40. McQuillan LP, Leung GK, Marsden PA, Kostyk SK, Kourembanas S. Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms. Am J Physiol 1994; 267: H1921-7.
41. Giles W, O'Callaghan S, Boura ALA, Walters WAW. Reduction in human fetal umbilical-placental vascular resistance by glyceryl trinitrate. Lancet 1992; 340: 856.